A5002506490- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Tracheal and airway disorders
- Corrosion Behavior and Inhibition
- Hydrogen embrittlement and corrosion behaviors in metals
- Cardiac Valve Diseases and Treatments
- Esophageal and GI Pathology
- Microbial Inactivation Methods
- Electrostatic Discharge in Electronics
- Coronary Interventions and Diagnostics
- Titanium Alloys Microstructure and Properties
- Aortic aneurysm repair treatments
- High Temperature Alloys and Creep
- Metal and Thin Film Mechanics
- Airway Management and Intubation Techniques
- Magnesium Alloys: Properties and Applications
- Orthopaedic implants and arthroplasty
- Fatigue and fracture mechanics
- Military Strategy and Technology
- Shape Memory Alloy Transformations
- High-Temperature Coating Behaviors
- Cardiac, Anesthesia and Surgical Outcomes
- Heart Rate Variability and Autonomic Control
- Bone Tissue Engineering Materials
Ollscoil na Gaillimhe – University of Galway
2008-2019
National University of Ireland
2014-2019
Local Government Association
2018
Greater London Authority
2015
University of Waikato
2011
DEVCOM Army Research Laboratory
2007-2009
University of Minnesota
2009
Monash University
2008
The Alfred Hospital
2008
Mater Misericordiae University Hospital
2007
Irreversible electroporation is an ablation technique being adapted for the treatment of atrial fibrillation. Currently, there are many differences reported in vitro and pre-clinical literature effective voltage threshold ablation. The aim this study a direct comparison different cell types within cardiovascular system identification optimal thresholds selective ablation.Monophasic pulses were delivered cuvette suspension model. Cell viability live-dead measurements three neuronal lines,...
Modulation of the cardiac autonomic nervous system (ANS) is a promising adjuvant therapy in treatment atrial fibrillation (AF). In pre-clinical models, pulsed field (PF) energy has advantage selectively ablating epicardial ganglionated plexi (GP) that govern ANS. This study aims to demonstrate feasibility and safety ablation GPs with PF during surgery primary efficacy outcome prolongation effective refractory period (AERP).In single-arm, prospective analysis, patients or without history AF...
MEPS Marine Ecology Progress Series Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsTheme Sections 608:93-103 (2019) - DOI: https://doi.org/10.3354/meps12800 A novel three-dimensional analysis of functional architecture that describes properties macroalgae as a refuge Colin Ware1,*, Jennifer A. Dijkstra1, Kristen Mello1, Andrew Stevens1, Brandon O'Brien2, William Ikedo1 1Center for Coastal and Ocean...
Abstract Background Endocardial radiofrequency ablation of epicardial ganglionic plexus (GP) for atrial fibrillation (AF) is complicated by myocardial damage. Objectives We hypothesized that an approach with a novel nitinol catheter system capable causing irreversible electroporation (IRE) direct current (DC) could selectively and permanently destroy GP without collateral injury. Methods Acute studies medium‐term terminal (mean survival, 1137 days) were performed seven dogs. In the acute...
Irreversible electroporation has emerged as a new modality to overcome issues associated with other energy sources for cardiac ablation. Strong evidence on the optimal, effective, and selective voltage threshold is lacking both in vitro preclinical vivo studies. The aim of this study examine optimal cell ablation types.Conventional monophasic biphasic pulses different field strength were delivered monolayer culture system cardiomyocytes, neurons, adipocytes. dynamics death mechanisms...
Anatomical correction of complete transposition the great arteries has potential advantage over intra-atrial repair in that left ventricle becomes systemic pump. To investigate importance this, we evaluated right and ventricular function 21 patients after anatomical Mustard or Senning operations. First-pass equilibrium-gated radionuclide angiography were used to measure ejection fractions between 17 78 (mean, 47) months 3 187 67) repair. The mean age patient groups at time study was 52 84...
Pulsed Field Ablation (PFA) has recently been proposed as a non-thermal energy to treat atrial fibrillation by selective ablation of ganglionated plexi (GP) embedded in epicardial fat. While some PFA-technologies use an endocardial approach, others access with promising pre-clinical results. However, each technology uses different and sometimes proprietary pulse application protocol, the comparation between vs. approach is almost impossible experimental terms. For this reason, our study,...