Traian V. Chirilă

ORCID: 0000-0001-6278-3168
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About
Contact & Profiles
Research Areas
  • Corneal Surgery and Treatments
  • Silk-based biomaterials and applications
  • Ocular Surface and Contact Lens
  • Hydrogels: synthesis, properties, applications
  • Corneal surgery and disorders
  • Advanced Polymer Synthesis and Characterization
  • biodegradable polymer synthesis and properties
  • Intraocular Surgery and Lenses
  • Electrospun Nanofibers in Biomedical Applications
  • Retinal and Macular Surgery
  • Periodontal Regeneration and Treatments
  • Ocular Disorders and Treatments
  • Polymer Surface Interaction Studies
  • Bone Tissue Engineering Materials
  • Antimicrobial Peptides and Activities
  • Photopolymerization techniques and applications
  • Aortic aneurysm repair treatments
  • Glaucoma and retinal disorders
  • RNA Interference and Gene Delivery
  • Wound Healing and Treatments
  • Chemical Synthesis and Analysis
  • Surgical Sutures and Adhesives
  • Neurobiology and Insect Physiology Research
  • Cardiac, Anesthesia and Surgical Outcomes
  • Aortic Disease and Treatment Approaches

Queensland Eye Institute
2015-2024

Universitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș
2019-2024

Queensland University of Technology
2015-2024

The University of Queensland
2015-2024

Advanced Pharma
2024

The University of Western Australia
2014-2023

Institute of Bioengineering and Nanotechnology
2020

Suzuki (Japan)
2018

N2 Biomedical (United States)
2010

Curtin University
2010

Membranes were prepared from fibroin, a protein isolated the domesticated silkworm (Bombyx mori) silk, and evaluated as potential substratum for corneal limbal epithelial cells. These membranes (i.e., B. mori silk fibroin [BMSF] membranes) cast dialyzed solutions of (4% w/v) dispensed into 35-mm-diameter culture dishes dried at room temperature (23–24°C). The resulting material was transparent, easy to handle, supported levels human (HLE) cell growth comparable that observed on tissue...

10.1089/ten.tea.2007.0224 article EN Tissue Engineering Part A 2008-07-01

Abstract A large number of hydrophilic sponges were prepared by polymerisation 2‐hydroxyethyl methacrylate in variable concentrations water (60‐90% wt) the initial monomer mixture. Concentration and type crosslinking agents (ethylene dimethacrylate (EDMA) hexamethylene (HDMA)) concentration redox initiators also changed. All examined cross‐section conventional environmental scanning electron microscopy. Micrographs indicated that, order to obtain with characteristics appropriate for...

10.1002/pi.4990320303 article EN Polymer International 1993-01-01

Background: The abdominal aortic aneurysm (AAA) is defined as an increase in diameter by more than 50% and associated with a high risk of rupture mortality without treatment. aim this study to analyze the role adventitial collagen photocrosslinking UV-A irradiation on biomechanical profile wall. Methods: This experimental structured two parts: first part includes vitro uniaxial evaluation porcine tissue subjected either short-term elastolysis or long-term collagenolysis attempt duplicate...

10.3390/jcm13020633 article EN Journal of Clinical Medicine 2024-01-22

Abstract The combination at the interface between two chemically identical polymers was investigated by light and electron (scanning, transmission) microscopy. constitute elements of a new type artificial cornea in which peripheral skirt is made from spongy poly(2‐hydroxyethyl methacrylate) (PHEMA) central optical zone homogeneous, transparent PHEMA. Their two‐phase along boundary fulfill formally requirements for an interpenetrating polymer network (IPN). procedure manufacture prosthesis...

10.1002/jbm.820280612 article EN Journal of Biomedical Materials Research 1994-06-01

ABSTRACT In an attempt to generate supramolecular assemblies able function as self‐healing hydrogels, a novel ureido‐pyrimidinone (UPy) monomer, 2‐( N ′ ‐methacryloyloxyethylureido)‐6‐(1‐adamantyl)‐4[1 H ]‐pyrimidinone, was synthesized and then copolymerized with N,N ‐dimethylacrylamide at four different feed compositions, using solution of lithium chloride in ‐dimethylacetamide the polymerization medium. The assembling process resulting copolymers is based on crosslinking through reversible...

10.1002/app.39932 article EN Journal of Applied Polymer Science 2013-09-21

Fibroin, the major proteinaceous component of silk fiber produced by larvae domesticated moth (Bombyx mori), has been widely investigated as a biomaterial for potential applications in tissue engineering and regenerative medicine. Following sol-gel transition, fibroin solutions can generate hydrogels that present certain advantages when employed biomaterials, especially if they are cross-linked. The subject this study was self-cross-linking through process induced enzyme horseradish...

10.1002/bab.1552 article EN Biotechnology and Applied Biochemistry 2017-02-21

We have reviewed the development and current status of therapies based on exposure to non-ionizing radiation (with a photon energy less than 10 eV) aimed at suppressing venous neointimal hyperplasia, consequentially avoiding stenosis in arteriovenous grafts. Due drawbacks associated with medical use ionizing radiation, prominently radiation-induced cardiovascular disease, availability procedures using is becoming noteworthy objective for research. Further, focus review was such improving...

10.3389/fcvm.2024.1356671 article EN cc-by Frontiers in Cardiovascular Medicine 2024-02-05

To elucidate the relatively short retention of crosslinked poly(1-vinyl-2-pyrrolidinone) hydrogels in eye when used as potential vitreous substitutes, a 14C-labeled hydrogel was produced and subjected to both vitro biodegradation assays vivo experiments. The polymer synthesized by free-radical copolymerization 99% 1-vinyl-2-pyrrolidinone with 1% 14C-methyl methacrylate presence ethylene glycol dimethacrylate (0.1%) crosslinking agent. protocol for assessing included incubation hydrolases...

10.1002/(sici)1097-4636(19980315)39:4<650::aid-jbm21>3.0.co;2-9 article EN Journal of Biomedical Materials Research 1998-03-15

A homopolymer of 1-vinyl-2 pyrrolidinone and its copolymer with 2-hydroxyethyl methacrylate, both cross-linked divinyl glycol, were produced as possible substitutes for the vitreous body eye. The hydrated polymers behaved like viscoelastic gels, displaying excellent physical optical properties. sterile gels (0.7-1.5 ml) injected into cavity rabbits, which previously underwent gas-mediated vitrectomy. Clinically, eyes quiet, exception transient opacities in vitreous. After 4 weeks, operated...

10.1163/156856296x00453 article EN Journal of Biomaterials Science Polymer Edition 1996-01-01
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