A5015360109- Retinal Diseases and Treatments
- Retinal Development and Disorders
- Glaucoma and retinal disorders
- Retinal and Optic Conditions
- Retinal Imaging and Analysis
- Retinal and Macular Surgery
- Corneal Surgery and Treatments
- Corneal surgery and disorders
- Intraocular Surgery and Lenses
- Ocular Surface and Contact Lens
- Virus-based gene therapy research
- Ocular Disorders and Treatments
- Ocular Oncology and Treatments
- Ocular Infections and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Ophthalmology and Visual Health Research
- Retinopathy of Prematurity Studies
- CRISPR and Genetic Engineering
- Cerebral Venous Sinus Thrombosis
- Hydrogels: synthesis, properties, applications
- Facial Trauma and Fracture Management
- Ophthalmology and Visual Impairment Studies
- Vascular Malformations Diagnosis and Treatment
- Acute Ischemic Stroke Management
- Connexins and lens biology
The University of Western Australia
2014-2024
Lions Eye Institute
2015-2024
Sir Charles Gairdner Hospital
1988-2020
Royal Perth Hospital
1980-2018
Lion Foundation
2017
Visual Sciences (United States)
2015
Singapore Eye Research Institute
2003
University of Puerto Rico at Carolina
2003
Center for Visual Communication (United States)
2000
De Montfort University
2000
The prevalence of diabetic complications is reported from a cross-sectional study rural subjects in Western Australia. Logistic-regression analysis has been used to discover potential risk factors associated with each complication. A distinction made between time-related variables (age, age at diagnosis, duration diabetes) and other variables. We have attempted identify the major for complication then examined effect after accounting important were found be diabetes retinopathy,...
Retinal degenerations and dystrophies are the major causes of genetically inherited blindness that characterized by apoptotic death photoreceptor cell layer retina. To date, no treatment exists for these diseases only recently have they been considered as candidates gene stem therapies. Here we report ability adult CD90+ marrow stromal cells (MSCs) to be induced activin A, taurine, EGF into (20-32%) expressing photoreceptor-specific markers rhodopsin, opsin, recoverin in vitro. were either...
The optimum mode of treatment for symptomatic pterygia would combine efficacy (a low recurrence rate) with safety (freedom from sight threatening complications), and not affect visual acuity adversely. pterygium excision conjunctival autografting in a sun exposed population which are prevalent has previously been questioned. A cross sectional review 93 eyes 85 patients was carried out by slit-lamp examination minimum 6 months (range 6-76 months) after free autografting. Case notes were...
The last major survey of adverse reactions to intravenous fluorescein angiography was performed more than 20 years ago. There have been two recent fatalities involving in Australia. It is important review the current incidence and latest literature on pathogenesis, prophylaxis alternatives angiography.A retrospective all sodium patients undergoing between June 1998 2004 undertaken. total number angiograms with were identified from photographic department database reaction register at Lions...
Long-term complications of pterygium excision and beta irradiation in 63 eyes 57 patients are described. The age the at treatment ranged from 27 to 69 years (mean 48 +/- 11), were assessed 3 20 later 12 3). pterygia excised, leaving bare sclera, total dose 750 5200 rads 3475 916) was given, except 7 who had repeated courses or overlapping fields irradiation. Scleral ulceration present 51 sectorial lens opacities with normal visual acuity (VA) 19 eyes. Radiation induced cataract occurred...
<h2>Abstract</h2><h3>Background</h3> We present the results of a Phase 2a randomized controlled trial investigating safety, and secondary endpoints subretinal rAAV.sFLT-1 gene therapy in patients with active wet age-related macular degeneration (wAMD). <h3>Methods</h3> All (n=32), (ClinicalTrials.gov; NCT01494805), received ranibizumab injections at baseline week 4, thereafter according to prespecified criteria. Patients group (n=21) (1×10<sup>11</sup>vg). were assessed every 4weeks 52...
Thermoplastic components subjected to cyclic loading may distort because of localized rises in temperature and/or fracture incremental (fatigue) crack propagation from microscopic cracks or defects produced during the manufacturing process by service conditions. The object present paper is show quantitatively how first mode failure, which referred as thermal softening, can be related loss compliance, specimen geometry and frequency magnitude load. results bending tests on...
<h3>Objectives:</h3> To determine whether a chorioretinal venous anastomosis could be created in humans and to evaluate the influence this has on patients with non-ischemic central retinal vein occlusions whom progressive visual loss developed. <h3>Design:</h3> Retrospective study. <h3>Patients:</h3> A total of 24 nonischemic loss. <h3>Intervention:</h3> An attempt was made create using laser photocoagulation enable obstructed blood enter choroid, thus bypassing site occlusion. <h3>Main...
<h3>AIMS</h3> To investigate the longevity and reproducibility of choroidal neovascularisation (CNV) induced by krypton laser photocoagulation in rat. The presence cell adhesion molecules (CAMs) vascular endothelial growth factor (VEGF) during development CNV was also studied. <h3>METHODS</h3> 67 pigmented rats underwent retinal laser. eyes were examined either single or serial fluorescein angiography at 3 days, 1, 2–3, 4–5, 7–8, 12 weeks post photocoagulation. expression CAMs (ICAM-1,...