A5039478528- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiovascular Disease and Adiposity
- Cardiovascular Health and Disease Prevention
- Lipoproteins and Cardiovascular Health
- Acute Myocardial Infarction Research
- Biomarkers in Disease Mechanisms
- Healthcare Systems and Public Health
- Cerebrovascular and Carotid Artery Diseases
- COVID-19 and healthcare impacts
- Cancer, Lipids, and Metabolism
- Elasticity and Material Modeling
- Coronary Interventions and Diagnostics
- Cardiomyopathy and Myosin Studies
- Cardiac Structural Anomalies and Repair
- Cardiovascular Effects of Exercise
- Cardiac, Anesthesia and Surgical Outcomes
- COVID-19 Clinical Research Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Blood Pressure and Hypertension Studies
- Advanced MRI Techniques and Applications
- Cardiac electrophysiology and arrhythmias
Penza State University
2020-2024
Aim. To study the lipid-lowering and pleiotropic effects of statin monotherapy combination with ezetimibe in patients postinfarction period, depending on achievement target level low-density lipoprotein cholesterol (LDL cholesterol) for 24 weeks. Materials methods. 114 myocardial infarction were included. Treatment was started monotherapy, insufficient efficacy, added. After weeks, 1st group included 38 people, 2nd – 76 patients. On 7–10th days weeks later, lipid profile, N-terminal fragment...
Objective. To study the effect of achieving target level total cholesterol (TC) and low-density lipoprotein (LDL–C) on parameters local vascular stiffness development chronic heart failure (CHF) in patients with ST-elevation myocardial infarction (STEMI). Design methods. The included 80 ST segment elevation (STEMI) aged 35 to 65 years. On 7–9th day STEMI, at 24th 48th weeks treatment atorvastatin 40–80 mg clinical symptoms were analyzed, lipid profile brain natriuretic peptide (BNP)...
Aim . To assess early predictors of pathological remodeling in patients after ST-elevation myocardial infarction (STEMI) using speckle-tracking echocardiography (STE). Material and methods The study included 114 STEMI aged 52 (44; 58) years. A two-dimensional was performed with the analysis standard parameters STE an strain rotational characteristics myocardium. In addition, brain natriuretic peptide troponin-I concentration determined. development post-infarction within 12-month follow-up...
Aim . To study the potential of global strain analysis using two-dimensional speckletracking echocardiography to predict heart failure (HF) in patients with ST-segment elevation myocardial infarction (STEMI) based on 6-month follow-up after revascularization. Material and methods The included 114 STEMI aged 52 (44; 59) years. Two-dimensional was performed standard parameters speckle tracking rotational characteristics myocardium. Concentration brain natriuretic peptide determined. endpoint...
Abstract Funding Acknowledgements Type of funding sources: None. Purpose to assess the relationship indicators global myocardial work left ventricle (LV) in patients with ST-segment elevation infarction (STEMI) hemodynamic and deformation parameters that traditionally characterize systolic function heart. Methods 45 people primary STEMI were included: 13 women 32 men aged 38 66 years (52.3 ± 7.4). Myocardial was confirmed by ECG, biomarkers (troponin I, CPK-MB) results coronary angiography....
Abstract Funding Acknowledgements Type of funding sources: None. Purpose to identify correlations between the indicators global work left ventricular (LV) myocardium with ejection fraction (EF) and post-systolic contraction index (iPSI) in healthy individuals. Methods study included 70 people: 34 men 36 women aged 21 61 years (mean age 39.3 ± 8.9 years). Inclusion criteria: absence complaints, anamnestic physical data indicating presence cardiovascular diseases / or damage other organs...
Abstract Funding Acknowledgements Type of funding sources: None. Objective to reveal the differences in global parameters myocardial work left ventricle (LV) patients with preserved LV ejection fraction (EF) after ST-segment elevation infarction (STEMI) and healthy individuals. Methods study included 45 people primary STEMI (group 1): 13 women 32 men aged 38 66 years (52.3 ± 7.4). The control group 2) consisted 70 individuals 39.3 8.9 years, including 34 36 women. Myocardial was confirmed by...
Abstract Funding Acknowledgements Type of funding sources: None. Objective to assess the ability standard echocardiography parameters and myocardial deformation on 7th-9th day STEMI predict risk pathological remodeling in postinfarction period. Methods study included 114 patients with ST-segment elevation infarction (STEMI) mean age was 52.3 ± 8.4 years, men prevailed 100 (88%). On day, has been performed using MyLab device (Italy) determination end-diastolic systolic volume indices (EDVi,...
Abstract Funding Acknowledgements Type of funding sources: None. Objective to predict pathological left ventricular (LV) remodeling using global parameters strain and twisting. Methods the study included 114 people with primary ST-segment elevation myocardial infarction (STEMI): 14 women 100 males aged 32 67 years (52.3 ± 8.4). STEMI has been confirmed by ECG data, cardiospecific biomarkers (troponin T, CPK-MB) coronary angiography - presence one infarct-related artery in absence...
Abstract Funding Acknowledgements Type of funding sources: None. Purpose To assess the degree impairment global myocardial function left ventricle in different localization infarction with ST segment elevation (STEMI) using speckle tracking echocardiography. Methods The study included 45 patients primary STEMI aged 38 to 66 years (52.3 ± 7.4). Myocardial was confirmed by ECG data, biomarkers (troponin T, CPK-MB) and results coronary angiography presence one infarct-related artery absence...
Objective: To assess the dynamics of regional arterial stiffness by volume sphygmography in patients with primary myocardial infarction ST segment elevation (STEMI) and without (NSTEMI) on background long-term effective lipid-lowering therapy. Design method: A total 24 people acute coronary syndrome were examined: 18 men (75%) 6 women (25%). The diagnosis was confirmed biomarkers necrosis, electrocardiography, angiography. STEMI diagnosed 91.6% individuals. average age 52.88 ± 9.55 years;...
Objective: To study the parameters of regional arterial stiffness in patients after acute myocardial infarction with ST segment elevation (STEMI) depending on achievement target level low-density lipoprotein cholesterol (LDL-C) during 24-week therapy atorvastatin 40–80 mg. Design and method: The included 80 STEMI (mean age 51.8 ± 8.2 years) first 24–96 hours from disease onset. diagnosis was confirmed by biomarkers necrosis, electrocardiography, coronary angiography. All received treatment...
Aim. To study in healthy individuals the gender and age characteristics of left ventricular (LV) myocardial work indicators, their correlations with global LV deformity indicators echocardiographic parameters characterizing systolic diastolic functions. Materials methods . 70 Healthy (n=70; 34 men 36 women; aged 39.3±8.9 years) were included study. The examination determined standard work: efficiency (GWE), constructive (GCW), wasted (GWW), index (GWI); as well myocardium deformation...