A5081659185- Cardiovascular Disease and Adiposity
- Cardiovascular Health and Disease Prevention
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Lipoproteins and Cardiovascular Health
- Healthcare Systems and Public Health
- Biomarkers in Disease Mechanisms
- Heart Rate Variability and Autonomic Control
- Blood Pressure and Hypertension Studies
- Cardiac electrophysiology and arrhythmias
- Cerebrovascular and Carotid Artery Diseases
- Acute Myocardial Infarction Research
- ECG Monitoring and Analysis
- Neurological Disorders and Treatments
- Elasticity and Material Modeling
- Coronary Interventions and Diagnostics
- COVID-19 Clinical Research Studies
- Liver Disease Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
- Obstructive Sleep Apnea Research
- Hormonal Regulation and Hypertension
- Advanced MRI Techniques and Applications
- Antiplatelet Therapy and Cardiovascular Diseases
- Pharmaceutical Economics and Policy
- Heart rate and cardiovascular health
Penza State University
2015-2024
Recently, there was plenty studies published on the arterial stiffness assessment, and importance of this proved as an independent prediction parameter, together with standard cardiovascular risk factors. In current document, we collect structure available clinical scientific data from abroad Russian studies. The aim publication is need to bring a reader demanded in practice ways wall information about conditions when it important restrictions, issues remaining unresolved.
Recently, there was plenty studies published on the arterial stiffness assessment, and importance of this proved as an independent prediction parameter, together with standard cardiovascular risk factors. In current document, we collect structure available clinical scientific data from abroad Russian studies. The aim publication is need to bring a reader demanded in practice ways wall information about conditions when it important restrictions, issues remaining unresolved.
Aim. Russian multicenter register of familial hypercholesterolemia (FH) was transformed into Register patients with FH and very high cardiovascular risk insufficient effect hypolipidemic therapy (RENESSANS Registry) in 2017 The aim RENESSANS maximal inclusion not only FH, but also those atherosclerotic diseases (CVD), who did achieve targeted level low density lipoprotein cholesterol (LDL-C) using drug therapy. Material methods. Registry is an open, national, observing study that includes...
The purpose of the study was to identify factors characterizing a decrease in LV global systolic function patients with ST-segment elevation myocardial infarction (STEMI) after revascularization using cardiac magnetic resonance imaging (MRI)-based ischemic injury pattern and laboratory parameters sensu left ventricular function. A total 109 STEMI were examined. underwent contrast-enhanced MRI 1.5 Tesla GE SIGNA Voyager (GE HealthCare, USA) on 7th-10th days from onset disease. According...
Aim . To assess the safety and efficacy of a single intravenous bolus non-immunogenic staphylokinase compared with alteplase in patients massive pulmonary embolism hemodynamic instability. Non-immunogenic is modified recombinant low immunogenicity, high thrombolytic activity fibrin selectivity. Material methods This multicenter, open-label, randomized, comparative clinical trial FORPE two parallel groups was conducted 23 centers Russia. A total 310 aged 18 years older instability computed...
The age is one of the main non-modified factors which reduces elasticity vessels and increases appearance atherosclerotic plaques. A number studies have revealed that in some people, vascular changes occur at a younger age, while presence only classical risk does not explain development cardiovascular events young people. This phenomenon described as syndrome early, or accelerated, aging (EVA). Aspects this premature process include endothelial dysfunction, increased arterial stiffness,...
The speckle tracking method allows one to quantify the temporal and spatial characteristics of myocardial contraction. Importantly, it does not depend on a scanning angle record movement speckles in 2D mode any direction, unlike tissue Doppler imaging. This examination is non-invasive, safe for patients, economically more beneficial comparison with other modern methods assessing heart contractility: MRI scintigraphy. Diagnostic thresholds are suggested obtaining peak values all types global...
Aim To identify early predictors for progression of chronic heart failure (CHF) in patients with ST-segment elevation myocardial infarction (STEMI). Material and methods The study included 113 STEMI aged 52 (95 % confidence interval, 36 to 65) years. 24-h ECG monitoring was performed assessment ventricular late potentials, QT dispersion, rhythm turbulence (HRT), variability (HRV); XStrain 2D echocardiograpy determination volumetric parameters, strain characteristics velocities; measurement...
Background. In order to provide personalized medicine and improve cardiovascular outcomes, a method for predicting adverse left ventricular remodeling (ALVR) after ST-segment elevation myocardial infarction (STEMI) is needed. Methods. A total of 125 STEMI patients, mean age 51.2 (95% CI 49.6; 52.7) years were prospectively enrolled. The clinical, laboratory, instrumental examinations performed between the 7th 9th day, 24 48 weeks, including plasma analysis brain natriuretic peptide (BNP),...
Introduction. Among the priorities of strategic development health care system there is telemedicine technologies implementation. Material and methods. The project was developed in Penza State University. For economic justification remote BP monitoring, technological scheme has been prepared, market capacity assessed competition analyzed, business model financial have developed, risks evaluated. Results. deployed at base with participation budget medical institution. patient provided a...
The recent data is considered on the prevalence, electrophysiology, mechanisms and risk factors of sudden cardiac death in patients after acute myocardial infarction. shown about Holter monitoring ECG as a method (these methods are use systems like Astrocard® Holtersystem, GE Healthcare MARS, medilog® DARWIN), that stratifies development. prognostic role importance specific parameters 24-hour studied, correlating with higher life-threatening rhythm disorders main death. estimation predictors...
Aim. To assess the impact of metabolic abnormalities in combination with obstructive sleep apnea on endothelial function and vascular stiffness parameters patients arterial hypertension 1-2 degrees. Material methods. Patients (n=74) syndrome were included into study. All underwent cardiorespiratory monitoring using SomnoCheck2 device (Wiennmann, Germany) divided two groups based its results. apnea-hypopnea index (AHI) <30 episodes per hour group 1 AHI >30 – 2. Monitoring ambulatory...
The problem of searching and large-scale implementation early diagnostic techniques cardiovascular diseases at the stage preclinical failure is still relevant.Novel methods for vessel stiffness assessment to stratify risk determine aim treatment intervention are certain provoke interest.The review considers modern aspects local an arterial wall, presents comparative data on ultrasound capabilities when using a standard B-mode new technique: echo-tracking.Software echo-tracking applications...
Aim. To study the diagnostic value of myocardial function parameters to assess their predictive ability in relation left ventricular (LV) global contractility patients after infarction (MI). Material and methods. The final analysis included 97 with MI aged 55,9±8,6 years. We performed standard two-dimensional echocardiography speckle tracking following parameters: work index (GlobalWI, mm Hg %); constructive (GlobalCW, wasted (GlobalWW, efficiency (GlobalWE). probability ejection fraction...
Background. Despite the global trend towards a decrease in mortality from cardiovascular pathology of atherosclerotic genesis, this group diseases continues to occupy leading position structure disability and among population many countries. Aim. Identification noninvasive markers arterial wall lesions associated with presence hypertension (AH) coronary heart disease (CHD) persons younger than 55 years. Materials methods. The study included 81 people. Three groups were distinguished them:...
The purpose of the study was to identify factors characterizing a decrease in LV global systolic function patients with ST-segment elevation myocardial infarction (STEMI) after revascularization using cardiac magnetic resonance imaging (MRI)-based ischemic injury pattern and laboratory parameters sensu left ventricular function. A total 109 STEMI were examined. underwent contrast-enhanced MRI 1.5 Tesla GE SIGNA Voyager (GE HealthCare, Chicago, IL, USA) on 7th–10th days from onset disease....
Aim . To study the effect of 48-week therapy with atorvastatin and ezetimibe on laboratory parameters, structural functional arterial characteristics heart failure markers in post-infarction period. Material methods A total 87 patients acute myocardial infarction were included. In first 24 hours, 80 mg/day was prescribed. During hospitalization, after 5-6, 24, 48 weeks, clinical paraclinical examinations performed. level low-density lipoprotein cholesterol (LDL-C) >1,4 mmol/l decrease...