A5045169841- Lipoproteins and Cardiovascular Health
- Cancer, Lipids, and Metabolism
- Lipid metabolism and disorders
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Hormonal Regulation and Hypertension
- Cholesterol and Lipid Metabolism
- Atherosclerosis and Cardiovascular Diseases
- Eicosanoids and Hypertension Pharmacology
- Fatty Acid Research and Health
- Plant biochemistry and biosynthesis
- Antioxidant Activity and Oxidative Stress
- RNA and protein synthesis mechanisms
- Liver Disease Diagnosis and Treatment
- Biomarkers in Disease Mechanisms
- Adipokines, Inflammation, and Metabolic Diseases
- Acute Ischemic Stroke Management
- Pharmaceutical Economics and Policy
- Metabolism and Genetic Disorders
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac pacing and defibrillation studies
- Natural Products and Biological Research
- Metabolomics and Mass Spectrometry Studies
- Blood Pressure and Hypertension Studies
- Acute Myocardial Infarction Research
- Cardiac Health and Mental Health
Acibadem City Clinic
2024
North-Western State Medical University named after I.I. Mechnikov
2017-2023
National Statistical Service of the Republic of Armenia
2020
National Medical Research Center of Cardiology
2020
Ministry of Health of the Russian Federation
2019
Russian Academy of Sciences
1998-2013
Institute of Experimental Medicine
1995-2005
Czech Academy of Sciences, Institute of Experimental Medicine
1996
Academy of Medical Sciences
1996
The Russian Society of Cardiology (RKO) With the participation of: National for Study Atherosclerosis (NOA), Association Endocrinologists (RAE), Cardiosomatic Rehabilitation and Secondary Prevention (RosOKR), Scientific Medical Therapists (RNMOT), Eurasian Cardiologists, (EAT), Gerontologists Geriatricians
Disclaimer РThe EAC/RNAS Guidelines represent the views of EAC and RNAS, were produced after careful consideration scientific medical knowledge, evidence available at time their publication. The RNAS is not responsible in event any contradiction, discrepancy, and/or ambiguity between other official recommendations or guidelines issued by relevant public health authorities, particular relation to good use healthcare therapeutic strategies. Health professionals are encouraged take fully into...
Familial hypercholesterolemia is a human monogenic disease caused by population-specific mutations in the low density lipoprotein (LDL) receptor gene. Despite thirteen different of LDL gene were reported from Russia prior to 2003, whole spectrum disease-causing alterations this country poorly known and requires further investigation provided current study.Forty-five patients with clinical diagnosis FH tested for apolipoprotein B (apoB) mutation R3500Q restriction fragment length analysis....
The high prevalence of persistent dyslipidemia in primary and specialized care patients treated with statins justifies the need to identify its reasons develop recommendations on treatment optimization. At present, Russian studies focusing achievement target lipid levels remain scarce, which emphasizes importance problem further investigation. Aim. Cross-sectional epidemiological study assessed statin-treated analysed predictors levels. Material methods. profile parameters were 1586...
Aim. Russian multicenter register of familial hypercholesterolemia (FH) was transformed into Register patients with FH and very high cardiovascular risk insufficient effect hypolipidemic therapy (RENESSANS Registry) in 2017 The aim RENESSANS maximal inclusion not only FH, but also those atherosclerotic diseases (CVD), who did achieve targeted level low density lipoprotein cholesterol (LDL-C) using drug therapy. Material methods. Registry is an open, national, observing study that includes...
Tactics for the management of patients with hypertriglyceridemia (HTG) is provided in conclusion Advisory Board. It demonstrated that HTG quite prevalent excessive body weight and an important component residual risk. creates additional conditions progression atherosclerosis, thus it recommended to test triglyceride high, very high extremely cardiovascular The indication pharmacological treatment reduce triglycerides concentration their level more than 2.3 mmol/l. Statins are drugs choice...
In opinion the Expert council provides management tactics for patients with hypertriglyceridemia (HTG). It is demonstrated that HTG a common condition in overweight and an important component of residual risk. creates additional conditions progression atherosclerosis, so level triglycerides (TG) recommended to be measured high, very high extremely risk level. An indication appointment drugs reduce concentration TG its more than 2,3 mmol/L. Statins are agents choice cardiovascular disease...
Холестерин липопротеидов невысокой плотности (ХС не-ЛВП) является вторичной целью коррекции дислипидемии, которую специалисты по диагностике, профилактике и терапии дислипидемий обсуждают более 20 лет. Вместе с тем показатель на данный момент еще не обрел заслуженной широты использования в клинической практике. В данной статье представлены результаты экспертного совета, рамках которого ведущие диагностике обсудили роль ХС не-ЛВП оценке сердечно-сосудистого риска. предложены целевые...
We used polymerase chain reaction-single-strand conformation polymorphism (PCR-SSCP) analysis to detect LDL receptor gene defects in the St. Petersburg population. have found a deltaG197 mutation several patients of Jewish origin. The named is shown be responsible for one-third (7/23) familial hypercholesterolemia (FH) cases Jews and absent Russian descent. prevalence consistent with its origin Lithuania or Poland. can easily detected polyacrylamide minigels because formation specific...
Hyperlipidemia is the main risk factor for diseases caused by atherosclerosis including ischemic stroke. This publication provides practical recommendations and an algorithm prescribing lipid-lowering therapy to post-ischemic stroke patients. The presents steps sequential administration of statins, ezetimibe, PCSK9 inhibitors achieve target levels low-density lipoprotein cholesterol.Гиперлипидемия является основным фактором риска развития заболеваний, обусловленных атеросклерозом, к которым...
Цель. Целью исследования явилась оценка эффективности и приверженности гиполипидемической терапии, частоты развития сердечно<со< судистых осложнений в течение 3<летнего периода наблюдения рамках регистра РЕНЕССАНС (Регистр пациентов с СГХС очень высокого сЕрдечно<Сосудистого риска недоСтАточной эффективНоСтью проводимой терапии). Материал методы. является открытым национальным наблюдательным исследованием включает больных семейной ги< перхолестеринемией (СГХС), а также...
Abstract Background There is a lack of local clinical epidemiological data describing the different heart failure (HF) phenotypes in Bulgaria. Objective Our goal was to describe demographic and characteristics patients with HF two cardiological hospitals. The primary objective secondary further specify profile chronic by phenotype current treatment patterns hospitalized patients. Primary outcome measures corresponding objectives were descriptive nature. Methods This retrospective...
Клинический пример пациента с семейной гиперхолестеринемией, вызванной новой мутацией c.1859G>C (p.W620S) в гене рецептора липопротеинов низкой плотности человека.