A5066639107- Lipoproteins and Cardiovascular Health
- Healthcare Systems and Public Health
- Health Systems, Economic Evaluations, Quality of Life
- Cancer, Lipids, and Metabolism
- Lipid metabolism and disorders
- Cardiac Health and Mental Health
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Hormonal Regulation and Hypertension
- Neurological Disorders and Treatments
- Computational Drug Discovery Methods
- Atherosclerosis and Cardiovascular Diseases
- Human Health and Disease
- Cardiac, Anesthesia and Surgical Outcomes
- Pharmaceutical Economics and Policy
- Metabolomics and Mass Spectrometry Studies
- Cardiac Imaging and Diagnostics
- Hormonal and reproductive studies
- Nutrition, Genetics, and Disease
- Erythrocyte Function and Pathophysiology
- Health and Medical Research Impacts
- Systemic Sclerosis and Related Diseases
- Cholesterol and Lipid Metabolism
- Cardiovascular Disease and Adiposity
- Sexual function and dysfunction studies
- Cardiovascular Effects of Exercise
National Medical Research Center of Cardiology
2020
National Statistical Service of the Republic of Armenia
2020
National Research Center for Preventive Medicine
1996-2019
Ministry of Health of the Russian Federation
1994-2019
Institute of Biomedical Chemistry
1994
Lomonosov Moscow State University
1993
The Russian Society of Cardiology (RKO) With the participation of: National for Study Atherosclerosis (NOA), Association Endocrinologists (RAE), Cardiosomatic Rehabilitation and Secondary Prevention (RosOKR), Scientific Medical Therapists (RNMOT), Eurasian Cardiologists, (EAT), Gerontologists Geriatricians
.
Disclaimer РThe EAC/RNAS Guidelines represent the views of EAC and RNAS, were produced after careful consideration scientific medical knowledge, evidence available at time their publication. The RNAS is not responsible in event any contradiction, discrepancy, and/or ambiguity between other official recommendations or guidelines issued by relevant public health authorities, particular relation to good use healthcare therapeutic strategies. Health professionals are encouraged take fully into...
Aim. To study the level of total cholesterol in patients at high and very cardiovascular risk real clinical practice correspondence their follow-up to current guidelines for treatment dyslipidemia issued by European Society Cardiology Atherosclerosis (2011), as well Russian National (2012). Material methods. Patients aged 30 years older who visited a general practitioner or cardiologist an outpatient clinic period from October 2013 July 2014 were included into study. Every patient filled out...
Tactics for the management of patients with hypertriglyceridemia (HTG) is provided in conclusion Advisory Board. It demonstrated that HTG quite prevalent excessive body weight and an important component residual risk. creates additional conditions progression atherosclerosis, thus it recommended to test triglyceride high, very high extremely cardiovascular The indication pharmacological treatment reduce triglycerides concentration their level more than 2.3 mmol/l. Statins are drugs choice...
In opinion the Expert council provides management tactics for patients with hypertriglyceridemia (HTG). It is demonstrated that HTG a common condition in overweight and an important component of residual risk. creates additional conditions progression atherosclerosis, so level triglycerides (TG) recommended to be measured high, very high extremely risk level. An indication appointment drugs reduce concentration TG its more than 2,3 mmol/L. Statins are agents choice cardiovascular disease...
Aim. To study the features of lipid-lowering therapy with rosuvastatin in high and very cardiovascular risk patients real outpatient practice. Material methods. Patients ≥30 years, visited internists or cardiologists district clinics period from October 2013 to July 2014 were included into study. Each patient fill questionnaire. Determination total cholesterol (TC) level was performed without special preparation using a portable photometric blood analyzer. Doctors prescribed when indicated,...
The current state of the Russian and foreign regulatory framework for off-label prescription medicines is presented in article. existing problems this specific drug therapy possible solutions are described. Unfortunately, there some gaps legislation regarding medication use. Based on clinical reality, cases, “off-label” drugs can be justified by condition patient, lack alternative approved drugs, availability published scientific data that create prerequisites effectiveness approach. When...
The article is devoted to the influence of magnesium on homeostasis body and, in particular, cardiovascular system. It describes importance presence and effects various key processes functions occurring body. reasons for lack ways replenish it both natural way (eating, certain foods) preparations are considered. provides examples large randomized studies that prove normal levels human health general state These show how deficiency increases risk diseases can be reduced. also shown which...
The high prevalence of lipid metabolism disorders in the Russian population and their contribution to cardiovascular risk require an optimization pharmacotherapy clinical practice. Aim . To study possible benefits statin therapy fixed doses for primary secondary prevention disease outpatient Material methods Ambulatory patients (n=300) with a or very hypercholesterolemia who had indications treatment diseases were included into non-randomized trial. Patients divided 2 groups. Group 1...
Aim. To study the possibilities of using multi-channel volume sphygmography (MCVS) in prophylactic medical examination population. Material and methods. Simultaneous 522 individuals older than 18 years was performed. Along with standard procedures provided by program synchronous registration blood pressure (BP) on four extremities MCVS At that a difference systolic BP between arms (ΔSBParm) legs (ΔSBPleg) ankle-brachial index (ABI) were automatically calculated. Values │ΔSBParm│ or...
Aim. To study the predictors of atherosclerotic lesions arteries identified through a multi-channel volume sphygmography (MCVS). Material and methods. Simultaneous survey 441 rural residents over 40 years old was performed. Synchronous registration blood pressure (BP) on four limbs using MCVS fulfilled, differences in systolic BP between arms ( Δ SBParm) legs SBPleg) were calculated. Ankle-brachial index (ABI) also evaluated. │ SBParm ≥15 mm Hg or SBPleg ABI≤0.9 considered as markers...
The review is focussed on the mechanisms of action, lipid-lowering activity, structural characteristics, and safety plant sterins stanols. Phytosterins phytostanols inhibit intestinal cholesterol (CH) absorption, therefore decreasing plasma CH levels. emphasis put prospective epidemiological studies representative samples, which demonstrated that concentrations phytosterins in patients with coronary heart disease (CHD) are substantially lower than CHD-free participants. A two-fold increase...
Болезни системы кровообращения - ведущая причина смертности в России и мире. В последние годы наблюдается рост сердечно-сосудистой патологии. Основу этой негативной тенденции составляет дислипидемия атеросклероз. Коррекция гиперхолестеринемии внесла наибольший вклад снижение от ИБС, однако многие пациенты не получают гиполипидемическую терапию или недостаточно эффективно контролируют факторы атеросклеротического риска. Для больных высокого очень сердечно-сосудистого риска особую актуальность...
The article discusses the current prevalence of hypercholesterolemia in everyday clinical practice patients different risk categories and approaches to its correction most frequently used guidelines. High practical health care with little change over time is shown. existing problems implementation principles a healthy lifestyle as basis for reducing cardiovascular possible solutions are described. Attention focused on low number taking statins, even less – reaching recommended target...
Acute ischemic heart disease is associated with alterations in the cardiac adenylate cyclase system response, although specificity and mechanism of these events are unknown. We studied characteristics inhibitory (G(i)) stimulatory (Gs) GTP-binding regulatory proteins (G proteins) erythrocyte membranes patients (n = 16) nonacute resulting from coronary atherosclerosis. Gs was measured by reconstitution resolved catalytic unit cholera toxin-catalyzed ADP-ribosylation a 42-kD protein; G(i)...
Одним из важнейших способов улучшения качества диагностики и коррекции артериальной гипертензии нарушений липидного обмена — двух факторов риска является повышение образовательного уровня врачей знание ими современных рекомендаций. Цель исследования оценить соответствие знаний (кардиологов терапевтов) первичного звена здравоохранения Курска современным рекомендациям по дислипидемиям возможность их повышения с помощью проекта. Материал методы. Проект охватывал всех участковых терапевтов...
Aim . To study the frequency of prescriptions various types lipid-lowering therapy and their effectiveness in outpatient clinical practice based on results a questionnaire primary care physicians. Material methods The was performed 2022 75 constituent entities Russian Federation with participation 1117 doctors working clinics. Most had work experience 10-20 years or more. Doctors polyclinics (therapists cardiologists, etc.) before start received instructions, questionnaires for filling out,...
Aim . To monitor the scope and effectiveness of lipid-lowering therapy (LLT) in out- inpatient settings among people hospitalized at National Medical Research Center for Therapy Preventive Medicine. Material methods Retrospective analysis randomly selected case records April-May 2012, 2015 2022 (n=658). Results From 2012 to 2022, proportion outpatients taking statins increased as follows: from 28,8 60,4% (from 22,2 73,3% high cardiovascular risk (CVR) 34,8 91,7% very CVR). Patients with CVR...
Aim. To evaluate factors contributing to development of inertness in doctors the primary care which treat and follow-up patients with cardiovascular diseases (CVD). Material methods. The anonymous poll was carried out among 184 physicians. questionnaire included information about sex, age, time conditions work, established stereotype practice, knowledge current guidelines on CVD treatment. study one-stage usage questionnaire. Results. High prevalence observed Only 43 (26,4%) had active...