A5018039651- Venous Thromboembolism Diagnosis and Management
- Acute Myocardial Infarction Research
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Acute Ischemic Stroke Management
- Atrial Fibrillation Management and Outcomes
- Healthcare Systems and Public Health
- Cardiac Imaging and Diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Long-Term Effects of COVID-19
- Atherosclerosis and Cardiovascular Diseases
- Cytokine Signaling Pathways and Interactions
- Blood Pressure and Hypertension Studies
- Vaccine Coverage and Hesitancy
- Cardiovascular Function and Risk Factors
- Human Health and Disease
- Cardiovascular Disease and Adiposity
- Renal Diseases and Glomerulopathies
- Birth, Development, and Health
- Antiplatelet Therapy and Cardiovascular Diseases
- Heparin-Induced Thrombocytopenia and Thrombosis
- Respiratory viral infections research
- Hemodynamic Monitoring and Therapy
- Cerebrovascular and Carotid Artery Diseases
- Coronary Interventions and Diagnostics
Ministry of Health of the Russian Federation
2015-2024
National Research Center for Preventive Medicine
2021-2024
Research Institute of Complex Problems of Cardiovascular Disease Russian Academy of Medical Sciences
2014-2023
Kemerovo State University
2018-2022
City Clinical Hospital
2019-2022
Thales (Portugal)
2020-2021
AstraZeneca (Sweden)
2021
Moscow State University of Medicine and Dentistry
2015-2020
Kemerovo Cardiology Center
2017
Kemerovo State Medical Academy
2011
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Создание руководства поддержано Советом по терапевтическим наукам отделения клинической медицины Российской академии наук.
Aim . To evaluate any cardiovascular abnormalities in the postoperative period, their prevalence and impact on course of period patients after non-cardiac surgery, which underwent examinations system. Material methods The study included 2937 patients. assessed end points were events (CVEs). Along with major adverse (MACE), we analyzed as follows: electrocardiographic ST-T abnormalities, acute or decompensated heart failure (HF), arrhythmias, episodes hypotension hypertension, bleeding,...
Recently, two following demographic trends have been clearly observed in the world: population aging and an increase prevalence of obesity. In February 2022, European Society for Clinical Nutrition Metabolism (ESPEN) Association Study Obesity (EASO) published first consensus guidelines definition diagnosis sarcopenic obesity, which characterizes by a combination excess adipose tissue with decrease muscle mass, strength impaired function. The purpose this review is to describe prevalence,...
Biological age has attracted increased attention of the medical community in recent years. It is individual for each person and currently there no clear classification dividing into groups that could help determine whether rate aging a particular normal or pathological. Today, scientists are conducting large number clinical laboratory studies to find optimal marker biological would meet all requirements. The review aim analyze summarize available data on mechanisms aging, development novel...
Until now, there remains a certain interest in studying the role of booster vaccination formation post-vaccination immunity against Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The variety vaccine platforms provides opportunity to choose them for population and healthcare workers, also allows taking into account individual characteristics each patient. Aim. To estimate incidence disease 2019 (COVID-19) as result using one type heterologous vaccines during primary repeated...
Introduction. Interferons are produced in response to the presence of pathogens cells and responsible for proper formation immune reaction. Preliminary data obtained studies properties recombinant interferon gamma (IFN-γ) that involved patients with community-acquired pneumonia (including bacterial), acute respiratory viral infection (ARVI), influenza new coronavirus have shown promising results.The purpose study was assess effect subcutaneous administration IFN-γ on changes vital signs...
Aim. To assess the features of diagnosis, treatment and outcomes pulmonary embolism (PE) in patients Russian hospitals. Material methods. The register included all hospitalized with PE identified by any diagnostic method. Duration inclusion was 12 months. In-hospital period management assessed. Information about provided 20 hospitals from 15 cities. Results. For April 15, 2018 to 2019, 609 were (women — 50,7%, mean age 63,0±14,5 years, minimum-maximum 19-94 years). Among known risk factors...
Highlights We have developed an integrated assessment framework for assessing regional quality of life the population residing in subjects Russian Federation 2017-2021 that includes four indices: Social-geographical, Demographic, Economic and Industrial-environmental. The study results confirmed importance influence on health regions. Further validity indices is needed to analyze impact individual indicators more depth, including within a specific nosology or groups. Abstract Aim. To develop...
One of the key tasks facing medical community and health professionals is identification patients at high risk hospitalization, including emergency one. Currently, various approaches are used to obtain information about certain predictors in a patient that associated with an increased hospitalization risk, but there no consensus on which them most effective. Aim. To summarize data from studies has analyzed prognostic value questionnaires or surveys associated risk. Material methods. We...
Aim. To assess the prognostic value of current scales and indices for risk stratification any surgical cardiovascular complications (CVC) in patients undergoing non-cardiac interventions. Material methods. This single-center cohort retrospective study was conducted who underwent surgery 2018 2020. Surgical postoperative (POCs) were assessed according to Clavien-Dindo classification. CVCs included cardio-vascular events (CVEs), major adverse cardiac (MACE), ST-T abnormalities on...
Background The development of acute kidney injury (AKI) in patients with coronavirus disease 2019 (COVID-19) is associated a high risk death. Published data demonstrate the possibility severe suffering from COVID-19. However, these are still controversial. Methods A total 1,280 proven diagnosis COVID-19 were included our study. was confirmed all using reverse transcriptase polymerase chain reaction test nasopharyngeal swab, and based on typical computed tomography findings. Demographic data,...
Background. Nephrotic syndrome (NS) is associated with a high risk of thrombotic complications. In this group patients, routine local tests for assessing hemostasis do not accurately reflect hypercoagulable state. Global functional hemostasis, including thrombodynamics (TD), are considered promising disorders in the blood coagulation system these patients. Aim. To compare rate hypercoagulability according to hemostatic and TD evaluate factors increased complications patients chronic...
to study the role of clinical factors and treatment tactics in development adverse outcomes patients with non-STelevation acute coronary syndrome (NSTEACS) for five years follow up.The included 415 NSTEACS observed 60±4 months from date discharge. Adverse events (AE) were unstable angina (UA), myocardial infarction (MI), ischemic stroke or patient's death. The favorable 5-year outcome was identified 200, - 178 patients. Statistical processing performed using STATISTICA 8.0 software package...
Background: To date, there is no evidence supporting the effectiveness of use any drugs for prevention COVID-19.However, we have a number promising at our disposal, which may be potential candidates in COVID-19 prevention.The main aim this study was to assess prevalence among healthy volunteers using nasal INF-γ as preventive measure. Methods and Results:In observational prospective study, used dosage form intranasal administration identify prophylactic effect high risk getting -medical...
Aim. To assess the prevalence, severity and prognostic value of renal dysfunction (RD) in patients with pulmonary embolism (PE) Russian population, as well to determine RD significance a marker that improves predictive ability current risk stratification systems. Material methods. From April 2018 2019, hospitalized due PE were sequentially included multicenter observational prospective registry SIRENA. was diagnosed at glomerular filtration rate (GFR) <60 ml/ min/1,73 m 2 . Risk early...
<h3></h3> В условиях продолжающейся пандемии COVID-19 при значительном разнообразии имеющихся вакцин крайне актуально изучение их влияния на систему гемостаза. <h3>ЦЕЛЬ ИССЛЕДОВАНИЯ</h3> рамках проспективного наблюдательного исследования изучить особенности тромбодинамики у лиц, вакцинированных против SARS-CoV-2 вакцинами Гам-КОВИД-Вак и КовиВак. <h3>МАТЕРИАЛ И МЕТОДЫ</h3> Проанализированы данные 99 вакцинированных, которые завершили первые 3 визита: из них 18 были привиты вакциной...
Highlights. Nowadays the only way to prevent a new coronavirus infection is vaccination. Overcoming such problems as gradual decrease in effectiveness of post-vaccination immunity and emergence strains SARS-CoV-2 possible due booster The review highlights current data on immunogenicity various vaccination regimens prospects for studying this issue Russian Federation. Abstract. COVID-19 pandemic going on, which makes it crucial spread disease. Vaccination specific prevention COVID-19. virus...
Aim. To evaluate the prevalence of oral anticoagulant therapy at outpatient and inpatient stages in patients hospitalized with ischemic stroke. Material methods . This open observational prospective real-world study included 114 atrial fibrillation (AF) confirmed Results. Only 26,3% AF a diagnosis stroke took anticoagulants (70% — direct (DOACs), 30% warfarin). At same time, among those taking warfarin, only one patient had normal international normalized ratio (INR) time hospitalization...
During the spread of an increasing number new variants Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2), it is extremely important not only to assess immunogenicity and efficacy, butalso safety various combinations vaccines. Excessive immune response associated signs symptoms may occur with varying frequency as expected from use Aim. To compare reactogenicity (heterologous homologous) vaccination regimens in a prospective observational study. Material methods . In individuals...
Along with efficacy and safety, it is extremely important to study the severity of humoral cellular immunity during not only vaccination, but also revaccination against Severe Acute Respiratory Syndromerelated CoronaVirus 2 (SARS-CoV-2). Aim. To compare immunogenicity (humoral immunity) various (heterologous homologous) regimens coronavirus disease 2019 (COVID-19) in a prospective observational study. Material methods . In individuals aged ≥18 years, absence contraindications two following...
To investigate factors that influence annual prognosis in patients with non-ST-segment elevation acute coronary syndrome ((NSTEACS) concurrent type 2 diabetes mellitus (DM2).The registry of NSTEACS (non-ST-segment myocardial infarction (NSTEMI), unstable angina) included 415 patients, them 335 had no carbohydrate metabolic disorders, 80 DM2. The follow-up period, during which the was evaluated one year after hospital discharge following index event. Lipidogram readings and serum levels...