- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Pain Management
- Enhanced Recovery After Surgery
- Nausea and vomiting management
- Hip and Femur Fractures
- Anesthesia and Neurotoxicity Research
- Nutrition and Health in Aging
- Pain Management and Opioid Use
- Intraperitoneal and Appendiceal Malignancies
- Cancer, Stress, Anesthesia, and Immune Response
- Esophageal and GI Pathology
- Hemodynamic Monitoring and Therapy
- Venous Thromboembolism Diagnosis and Management
- Intensive Care Unit Cognitive Disorders
- Gastric Cancer Management and Outcomes
- Tracheal and airway disorders
- Anesthesia and Sedative Agents
- Frailty in Older Adults
- Hepatocellular Carcinoma Treatment and Prognosis
- Migraine and Headache Studies
- Pediatric Pain Management Techniques
- Clinical Nutrition and Gastroenterology
- COVID-19 and healthcare impacts
- Gastrointestinal Tumor Research and Treatment
- Healthcare Systems and Public Health
P.A. Hertzen Moscow Oncology Research Institute
2014-2025
Peoples' Friendship University of Russia
2024-2025
Ministry of Health of the Russian Federation
2011-2024
Medical Radiological Research Center
2020-2024
Ministry of Health
2019
Sechenov University
2018
This article described the main theses of clinical guidelines Russian Federation Anesthesiologists and Reanimatologists on postoperative pain management. The classification, etiology pathogenesis pain, basic principles algorithms for diagnosing regional systemic pharmacotherapy in various fields surgery are consistently presented. Multimodal analgesia is detail as a key concept current approach to treatment pain. All presented information based evidence-based medical data obtained by foreign...
Создание руководства поддержано Советом по терапевтическим наукам отделения клинической медицины Российской академии наук.
BACKGROUND: The use of tyrosyl-D-arginyl-phenylalanine-glycine amide, a highly specific μ1-opioid receptor agonist, is one the most promising new approaches for treatment acute postoperative pain. AIMS: To investigate efficacy and safety amide in cancer patients depending on type anesthesia used various types surgical interventions. MATERIALS AND METHODS: study included 80 aged 29 to 86 years (mean age 66 (Q1;Q3 – 59;71 years)), 46 (57.5%) men 34 (42.5%) women, with physical status I–III...
INTRODUCTION: Identification of risk factors that cause a high probability an unfavorable outcome in the postoperative period is urgent problem. The creation national databases (registries) makes it possible to cover certain patient population by identifying its predictors. Existing registries differ criteria for inclusion study, characteristics populations studied, and there often no common view on classification outcomes. OBJECTIVE: Creation Russian calculator complications mortality....
Arterial hypertension is the most common and socially significant disease among adult population, which associated with development of cardiovascular other complications during non-cardiac surgery. In 2020, all-Russian public organization Federation Anesthesiologists Intensive Care Specialists developed recommendations for perioperative management patients concomitant hypertension, have no analogues in world literature. second edition, from standpoint evidence-based medicine, section...
Non-invasive methods for determining blood hemoglobin (Hb) concentration are urgently needed to avoid the painful and time-consuming process of invasive venous sampling. Many such rely on assessing average attenuation light over a tissue area where is dominant chromophore, without separating those areas corresponding vessels bloodless tissue. In this study, we investigate whether it possible determine levels in by changes intensity when passing through large comparison adjacent tissues,...
INTRODUCTION: The development of clinical and methodological recommendations improves the quality medical care reduces risk complications. OBJECTIVE: To analyze “Perioperative management patients with coronary heart disease”, concomitant pathology valvular apparatus” morbid obesity” using modified Delphi method. MATERIALS AND METHODS: A method was used two rounds questionnaires to develop a consensus. agreement specialists reached in three stages: preparatory stage, discussion stage...
Highlights The developed prediction model is a simple and accurate method for assessing the postoperative risk of cardiovascular complications in large population patients undergoing non-cardiac surgery. Its widespread use will optimize perioperative management tactics improve surgical results. Aim. To develop predicting abdominal surgery compare its accuracy with foreign analogs validated on domestic cohort patients. Methods. multicenter prospective study included 8 241 over 18 years age...
Purpose: Our study aimed to assess whether the type of regional anesthesia influenced incidence chronic postthoracotomy pain syndrome (CPTPS).
Perioperative management of elderly patients remains one the most difficult tasks modern anesthesiology. Compared with younger patients, people over 60 years age have a higher risk developing adverse postoperative outcomes, as result age-related decline in physiological functions, presence several concomitant diseases, polypragmasia, cognitive dysfunction and specific geriatric syndromes, such frailty. More than 25 % this category chronic diseases cardiovascular, nervous, endocrine,...
INTRODUCTION: Risk assessment and identification of a group patients with high probability developing an unfavorable outcome is the basis for effective prevention postoperative adverse events. OBJECTIVE: The purpose study was to determine structure frequency co-existing diseases in preoperative period associated outcomes. MATERIALS AND METHODS: analysis parameters 8,241 STOPRISK database operated on abdominal pelvic organs from July 1, 2019 April 30, 2022 carried out. RESULTS: Co-existing...
A significant proportion of patients undergoing non-cardiac surgery receive therapy with angiotensin converting enzyme (ACE) inhibitors/angiotensin II receptor blockers (ARBs), which are usually prescribed for treatment arterial hypertension and CHF. Current guidelines fail to provide clear consensus on whether it is worth discontinuing ACEi/ARBs before surgery. The aim this research was assess the contribution pre-op withdrawal development postoperative complications in after abdominal...
Introduction. Despite the advances in modern anesthesiology, it is impossible to guarantee a safe course of anesthesia, and even with planned surgical interventions, there risk death. At present, no unanimity approaches assessing perioperative risk, many systems for determining this have not been validated Russia. The question contribution pre-operative factors likelihood an unfavorable outcome also remains open, which requires large multicenter national studies. Objectives. To assessment...
The article provides the main statements of guidelines for anesthesia and intensive care patients with coronavirus disease (COVID-19), developed by Federation Anesthesiologists Reanimatologists Russia. In process developing recommendations, publications official websites Russian Federation, electronic databases RSCI, PubMed, MEDLINE, EMBASE Cochrane Central Register Controlled Trials (CENTRAL) were analyzed developers independently each other. date last search query was February 01, 2021. To...
INTRODUCTION: Advances in modern anesthesiology have significantly reduced the risk of anesthesia compared to last century, however, level perioperative in-hospital mortality after elective major abdominal surgery is still high at moment. Poor outcome prediction cornerstone individualized management high-risk patients aimed preventing complications. Despite fact that a large number assessment tools been developed over past decades, accuracy forecast far from required. According literature...
The article provides the main statements of guidelines for anesthesia and intensive care patients with coronavirus disease (COVID-19), developed by Federation Anesthesiologists Reanimatologists Russia. In process developing recommendations, publications official websites Russian Federation, electronic databases RSCI, PubMed, MEDLINE, EMBASE Cochrane Central Register Controlled Trials (CENTRAL) were analyzed developers independently each other. date last search query was June 29, 2020. To...
Background. The most important component of multimodality treatment cancer is nutritional support. management the correct full support in perioperative period will help to maintain body weight and muscle function, reduce frequency development postoperative complication severity hospital length stay. To provide necessary cover all energy requirements patients (30 kcal/kg per day), protein (1.5 g protein/kg day) eicosapentaenoic acid (2 g/day), applying clinical nutrition through appropriate...
Purpose of the study. To determine effect nutritional deficiency and therapy on quality life patients with gastric cancer at stage surgical treatment. Patients methods. In Thoracoabdominal Department P. Herzen Moscow Oncology Research Institute within 2017– 2019 treatment malignant neoplasms was evaluated in 62 (36 men 26 women) aged 34 to 79 years (mean age 61.9 ± 9.55). At outpatient stage, were divided into 2 groups: 1st (main) group, received nutritive support specialized mixtures for 10...
Background. Metabolic changes due to the progression of cancer and its aggressive treatment, lead decreased food intake, related with development anorexia-cachexia syndrome (CACS) because complex interactions between pro-inflammatory cytokines host metabolism. Beyond physical metabolic consequences, patients are often suffering from psychological distress, including depression. Material Methods . A literature search analysis data was conducted in PubMed Medline databases since 2000 purpose...
The article is devoted to the most relevant topic at present — possibilities of providing full medical care cancer patients in context spread COVID‑19 coronavirus pandemic. Cancer are vulnerable group, because they high risk from position immunosuppression, which often combined with other factors for infection: old age, diabetes and cardiovascular diseases. Procrastination delaying start antitumor therapy unacceptable, since it inevitably leads a deterioration treatment results, an increase...
manipulations and without pericardial opening or resection, the rate of PAF was 25.5% (12/47) 7.3 (25/343), respectively (p=0.001). Perioperative transfusion therapy performed in 15.9% (85/532). In this group, frequency episodes higher accounted for 20% (23/85%) versus 8.7% (39/447) patients who did not need any blood (p=0.01). continuous thoracic epidural analgesia significantly lower than that general anesthesia group [7.9% (15/190) 13.7% (47/342), (p=0.04)]. The intensive care unit (ICU)...