A5077085011- Lung Cancer Diagnosis and Treatment
- Myasthenia Gravis and Thymoma
- Tracheal and airway disorders
- Metastasis and carcinoma case studies
- Pleural and Pulmonary Diseases
- Neuroendocrine Tumor Research Advances
- Gastric Cancer Management and Outcomes
- Lung Cancer Treatments and Mutations
- Esophageal Cancer Research and Treatment
- Cancer Diagnosis and Treatment
- Medical Imaging and Pathology Studies
- Lung Cancer Research Studies
- Radiomics and Machine Learning in Medical Imaging
- Congenital Diaphragmatic Hernia Studies
- Esophageal and GI Pathology
- Neuroblastoma Research and Treatments
- Thyroid and Parathyroid Surgery
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Sarcoma Diagnosis and Treatment
- Multiple and Secondary Primary Cancers
- Cardiac tumors and thrombi
- Meningioma and schwannoma management
- Soft tissue tumor case studies
- Brain Metastases and Treatment
- Bone Tumor Diagnosis and Treatments
P.A. Hertzen Moscow Oncology Research Institute
2015-2024
Ministry of Health of the Russian Federation
2012-2024
Cancer Research Center
2021-2023
Research Medical Center
2020-2022
Ministry of Health
2020
Medical Radiological Research Center
2018
Purpose: Our study aimed to assess whether the type of regional anesthesia influenced incidence chronic postthoracotomy pain syndrome (CPTPS).
Conventional thoracoscopy, routinely performed in patients with pleural diseases, is not always conclusive staging of spread. Fluorescence diagnosis (FD) 5-aminolaevulinic acid (5-ALA) has been used the diagnostic purpose for various malignancies. The impact fluorescence thoracoscopy on and malignancies was examined. A total 23 non-conclusive effusions were enrolled prospective single-institution trial. Eligible administered 25 mg/kg 5-ALA ('Alasense', Niopik, Russian Federation) per os 3 h...
The purpose of this study was to evaluate the efficiency our newly designed tactile mechanoreceptor in detection pulmonary lesions during thoracoscopy. Twenty-seven patients with peripheral undetermined subpleural solitary detected on computed tomography were included a prospective non-randomized trial. All nodules from 7 18 mm diameter located deep lung parenchyma (≥10 surface). underwent thoracoscopic exploration diagnostic intent. Instrumental palpation forceps performed first, followed...
Lung cancer has the highest morbidity rate among all malignant tumors in men and mortality women Russia. In total, 49 145 new cases of lung were registered (diagnosed) Russia 2019. The majority are related to exogenic carcinogens mainly tobacco smoke. For several decades surgical resection with preoperative cytotoxic therapy was an optimal approach for maximal cure rate. This year recommendations updated strategies including adjuvant anti-PD-L1 atezolizumab following completion chemotherapy...
Abstract Background Lung cancer, which is diagnosed two to three times more frequently in patients over the age of 70, a leading cause cancer-specific mortality. Given elevated risk morbidity and mortality, surgical intervention may not always be most appropriate primary treatment option. This study aims evaluate specific factors associated with postoperative mortality elderly optimize patient selection therefore improving outcomes. Patients methods The encompassed cohort 73 aged 75 above...
Perforated cystic mediastinal teratoma is rare. The diagnosis of this condition and a clear demonstration its associated complications are important for defining the surgical approach. We report clinical manifestation, computed tomography (CT) ultrasound findings case mature perforating into lung. Ultrasound features teratoma–lung fistula have not been previously described. pathological examination confirmed perforation lung without evidence pulmonary invasion.
Analysis of exhaled breath condensate (EBC) is a promising non-invasive method to diagnose respiratory diseases. Most researchers emphasize the importance proteomic analysis EBC for early diagnosis certain diseases including lung cancer. This study was aimed at identification potential biomarkers neoplastic disorders in patients with cancer using high-performance liquid chromatography and high resolution mass-spectrometry. The involved 26 carcinoma (21 males, 5 females, mean age 57 ± 12...
Postoperative complications after pneumonectomy for NSCLC depend on the extension of surgery, comorbidities and accurate registration any adverse event. The aim study was to evaluate short-term results standard extended in patients according TMM grading system.We included 216 consecutively submitted at our institution from January 2009 December 2013 retrospective performed data prospectively collected an electronic clinical database. All were divided into two different groups: (n=142) (n=74)...
Primary chondrosarcoma of the trachea is an extremely rare non-epithelial neoplasm with only few cases published in literature. We present a case tracheal extensive extraluminal growth. operated patient obstructive tumour upper third via partial sternotomy. Before surgery, Hanarostent was put into to treat life-threatening stenosis. Postoperative period uneventful. discuss incidence, clinical presentation and treatment options patients tumours. In some cases, multidisciplinary approach...
manipulations and without pericardial opening or resection, the rate of PAF was 25.5% (12/47) 7.3 (25/343), respectively (p=0.001). Perioperative transfusion therapy performed in 15.9% (85/532). In this group, frequency episodes higher accounted for 20% (23/85%) versus 8.7% (39/447) patients who did not need any blood (p=0.01). continuous thoracic epidural analgesia significantly lower than that general anesthesia group [7.9% (15/190) 13.7% (47/342), (p=0.04)]. The intensive care unit (ICU)...
To compare an effectiveness of thoracic epidural anesthesia/analgesia, paravertebral and intercostal blockades in prevention chronic post-thoracotomy pain syndrome (CPTPS) oncosurgery.There were 300 patients who underwent open surgery including lobectomy or pneumonectomy. Patients randomized into 3 groups depending on type anesthesia: TEA (n=100) - combined general anesthesia; PVB (n=50) ICB anesthesia was supplemented by blockade after removal the drug.CPTPS incidence 34 40% 6 months...
Optimization of diagnosis and treatment patients with solitary fibrous tumor pleura, analysis overall survival disease-free survival, predictors recurrence.There were 66 pleura (26 men 40 women) aged 57.6 years (range 26-80 years). Asymptomatic course was found in 29 (44%) patients, various symptoms - 37 (56%) patients. Thoracotomy applied 36 thoracoscopy 30 Immunohistochemical examination included definition Stat6 expression.Benign variant SFT diagnosed 50 (75.7%) malignant 16 (24.3%) STAT6...
Isolated bronchus resection for central cancer was performed in 25 patients including preoperative bronchoscopic removal of exophytic tumor 20 (80%) observations thoracic department P. Gertsen Moscow Research Cancer Institute. According to morphological study typical carcinoid diagnosed 23 (92%) patients, atypical - 2 (8%) cases. All underwent conventional mediastinal lymphadenectomy. Postoperative complications after developed 6 (33.3%) patients. There were no deaths. Overall 5- and 10-year...
Background. esophageal cancer (ec) is one of the most aggressive malignancies gastrointestinal tract. chemoradiation therapy standard care for locally advanced ec. The purpose study was to evaluate efficacy given alone and in combination with surgery patients thoracic cancer. Material Methods . From January 1, 2012 december 31, 2021, a total 940 were registered regional registry, which 178 selected concurrent chemoradiotherapy (CRT) at clinical stages I–III. thirty seven who received CRT...
To create a prognostic model determining the risk of tension pneumothorax and need for intraoperative installation additional drainage after thoracoscopic lobectomy.
The paper describes the state-of-the-art of surgical treatment in patients with neuroendocrine tumors lung. It considers their classification, morphological diagnosis, and possibilities instrumental diagnosis. Distinctive clinical criteria for carcinoid, large-cell small-cell cancer lung are characterized.
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To analyze immediate and long-term results of anatomical resections for lung cancer with subsequent comparison the segmentectomy lobectomy in patients peripheral NSCLC stage IA1-2.There were 52 sublobular non-small cell carcinoma carcinoid T1a-bN0M0, IA1-2 stage. 3D-CT reconstruction separation bronchial vascular structures was used to schedule complex segmentectomy. We retrospectively analyzed 200 cT1a-bN0M0 (NSCLC) tumor dimension ≤2 cm who underwent (n=148) (n=52). Mortality, morbidity...
Background . Air-leak after lung resection is a common complication occurring in 30–50 % of patients immediately surgery. The prolonged air-leak (PAL) serious problem if it lasts more than 5 days surgery with the reported incidence 15 %. Despite progress thoracic including energy-based vessel-sealing devices and digital drainage systems, there no universal agreement on optimal treatment air-leaks. T he aim study : to improve postoperative outcomes PAL by optimization algorithm. Material...