Natalia Dengina

ORCID: 0000-0002-6608-2745
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About
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Research Areas
  • Advances in Oncology and Radiotherapy
  • Advanced Radiotherapy Techniques
  • Lung Cancer Diagnosis and Treatment
  • Renal cell carcinoma treatment
  • Brain Metastases and Treatment
  • Cancer Immunotherapy and Biomarkers
  • Bladder and Urothelial Cancer Treatments
  • Gastric Cancer Management and Outcomes
  • Global Cancer Incidence and Screening
  • Management of metastatic bone disease
  • Cancer Diagnosis and Treatment
  • COVID-19 and healthcare impacts
  • Urological Disorders and Treatments
  • Radiation Dose and Imaging
  • Esophageal Cancer Research and Treatment
  • Multiple and Secondary Primary Cancers
  • Lung Cancer Treatments and Mutations
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Urinary and Genital Oncology Studies
  • Effects of Radiation Exposure
  • Lung Cancer Research Studies
  • Breast Implant and Reconstruction
  • Renal and related cancers
  • BRCA gene mutations in cancer
  • Mast cells and histamine

State Healthcare Institution "Regional Clinical Oncological Dispensary"
2017-2024

Ulyanovsk Regional Oncology Center
2016-2023

Regional Cancer Center
2023

Ulyanovsk State University
2020

Oregon Health & Science University
2017

Banner Health
2017

Tyrosine kinase inhibitors (TKIs) and checkpoint have been established as effective treatment for metastatic renal cell carcinoma (mRCC), but only a minority of patients achieve complete response. Additional strategies are necessary to improve these agents' efficacy.Patients with stable disease at least 4 months on TKI or were included. Stereotactic body radiotherapy (SBRT) was delivered an organ comparable lesions, where one lesion in the target other intentionally left untreated (control...

10.1136/esmoopen-2019-000535 article EN cc-by-nc ESMO Open 2019-01-01

В статье представлены результаты голосования I Cанкт-Петербургского международного консенсуса по диагностике и лечению рака молочной железы «Белые ночи 2024», посвященного наиболее актуальным спорным вопросам диагностики, хирургической тактики, лучевой терапии системного лечения данной категории пациентов. Под председательством член-корреспондента РАН, профессора Владимира Федоровича Семиглазова в международном консенсусе приняли участие 38 экспертов области диагностики (РМЖ),...

10.37469/0507-3758-2024-70-6-of-2194 article RU cc-by-nc-nd Voprosy Onkologii 2025-01-22

The COVID-19 pandemic has profoundly affected cancer care worldwide, including radiation therapy (RT) for breast (BC), because of risk-based resource allocation. We report the evolution international RT practices during beginning pandemic, focusing on differences in treatment recommendations between countries.Between July and November 2020, a 58-question survey was distributed to oncologists (ROs) through professional societies. Changes decision making first surge were evaluated across six...

10.1200/go.23.00010 article EN cc-by-nc-nd JCO Global Oncology 2023-07-01

Abstract Background To our knowledge, there is no clinical data pertaining to COVID-19 outcomes and safety of vaccination in Russian patients with genitourinary (GU) malignancies. Aim analysis was describe the characteristics infection course as well preliminary efficacy Gam-COVID-Vac vaccine active GU Methods Patients were retrospectively identified at nine cancer centers different regions. included if diagnosed by a polymerase chain reaction. Data from additional cancers who had positive...

10.1186/s13045-021-01205-z article EN cc-by Journal of Hematology & Oncology 2021-11-13

Background. esophageal cancer (ec) is one of the most aggressive malignancies gastrointestinal tract. chemoradiation therapy standard care for locally advanced ec. The purpose study was to evaluate efficacy given alone and in combination with surgery patients thoracic cancer. Material Methods . From January 1, 2012 december 31, 2021, a total 940 were registered regional registry, which 178 selected concurrent chemoradiotherapy (CRT) at clinical stages I–III. thirty seven who received CRT...

10.21294/1814-4861-2023-22-5-84-95 article EN cc-by Siberian Journal of Oncology 2023-11-15

Introduction. For an extended period, numerous studies have been conducted to find the optimal treatment regimen for esophageal cancer. Chemoradiotherapy has demonstrated satisfactory results in of localized and locally advanced forms this disease. However, search best chemotherapy combination with radiotherapy remains a current focus many researchers. Aim. To evaluate effectiveness safety chemoradiotherapy (CRT) using FOLFOX patients Materials methods. A prospective study was at Ulyanovsk...

10.21518/ms2024-527 article EN cc-by-nc-nd Meditsinskiy sovet = Medical Council 2024-12-22

Primary gastric melanoma is an extremely rare disease. Melanoma of upper gastrointestinal tract usually occurs as metastasis from a primary skin tumor in 1 to 4 % cases. The paper describes case report female patient who received complex therapy at the State Healthcare Institution Ulyanovsk Regional Clinical Oncology Dispensary.

10.18027/2224-5057-2020-10-35-40 article EN cc-by Malignant tumours 2020-10-17

Current approaches to the treatment of patients with metastatic malignant tumors have changed significantly over past decade. Instead a purely palliative systemic or just supportive therapy, large proportion receive an aggressive local directed not only primary tumor, but also foci, and number studies demonstrate advantage such approach. This review provides information on role radiation therapy as method cancer oligometastases.

10.18027/2224-5057-2020-10-3-5-14 article EN cc-by Malignant tumours 2021-06-12

Background. Tyrosine kinase inhibitors (TKI) and checkpoint (CI) have been established as effective treatment for mRCC, but only a minority of patients achieves complete response additional strategies are necessary to improve the efficacy these agents. We designed prospective phase 1b «Volga» study determine safety extracranial SBRT in with clear-cell mRCC. Methods. Patients were included if they had stable disease at least 4 months on TKI or CI. was delivered an organ multiple comparable...

10.18027/2224-5057-2019-9-3-57-64 article EN cc-by Malignant tumours 2019-12-14

Chemoradiotherapy is the cornerstone in treatment of patients with locally advanced lung cancer. However, according to official statistics Russia, such extremely rare, despite fact that primary cancer detected more than 30 % cases. One most frequent obstacles for wider use chemoradiotherapy its high toxicity intrathoracic tumors. This review presents common complications and methods their prevention, control.

10.33667/2078-5631-2019-2-17(392)-43-48 article EN cc-by Medical alphabet 2019-11-27

Radical prostatectomy can provide an excellent local control in patients with localized prostate cancer. However, some risk factors (extracapsular spread of tumor (pT3a), seminal vesicle invasion (pT3b) or the presence cells resection margin (R1), and others.) require postoperative radiation therapy. The most debated issue is timing radiotherapy (during period delayed, case increasing levels PSA), as well criteria for selection candidates this treatment. article examines arguments "pro"...

10.18027/2224-5057-2013-1-41-46 article EN cc-by Malignant tumours 2015-05-20

In 2005 the Oxford meta-analysis of individual patient data from many trials showed no benefit to postmastectomy radiotherapy in node-negative breast cancer patients but reduced 5-year local recurrence and 15-year mortality with node-positive disease who underwent axillary lymphnode dissection. Despite these data, there is still some debate over appropriateness 1 3 involved lymph nodes. Neoadjuvant chemotherapy leads clinical pathological response a certain proportion patients. So far,...

10.18027/2224-5057-2017-2-62-66 article EN cc-by Malignant tumours 2017-01-01

В настоящее время существует две основных парадигмы в выборе объема облучения лимфоколлектора при немелкоклеточном раке легкого: 1. Включение объем только очевидно пораженных тканей легкого и регионарных лимфоузлов, вовлеченных опухолевый процесс с исключением из полей лимфоузлов гипотетическим микрораспространением опухолевых клеток. Основная цель таком – возможность подведения максимальных курабельных доз излучения (более 60 Гр) за счет уменьшения общего снижения лучевой токсичности. 2....

10.18027/2224-5057-2017-3s1-22-25 article RU cc-by Malignant tumours 2017-01-01

Радиационная онкология представляет собой особую клиническую дисциплину, рождённую на стыке нескольких наук.Её развитие в последние годы настолько динамично, что владеть полном объёме всей новой информацией отношении метода лучевой терапии, не посвящая этому свою каждодневную деятельность, невозможно.Именно поэтому присутствие радиотерапевта составе мультидисциплинарной команды специалистов, принимающих решение о лечении онкологического больного, строго обязательно.Именно эта идея становится...

10.31917/1804343 article RU Practical oncology 2017-12-30

11001 Background: Radiation oncologists (ROs) in Russia face a number of unique professional difficulties including lack standardized training and continuing medical education. To combat this, under the auspices Russian Society Clinical Oncology (RUSSCO), our group has developed series ongoing in-person interactive contouring workshops that are held during major oncology conferences Moscow, Russia. Since November 2016 each workshop, we utilized web-based open-access three-dimensional atlas...

10.1200/jco.2018.36.15_suppl.11001 article EN Journal of Clinical Oncology 2018-05-20
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