A5065713063- Breast Cancer Treatment Studies
- Advanced Radiotherapy Techniques
- Advances in Oncology and Radiotherapy
- Breast Implant and Reconstruction
- Global Cancer Incidence and Screening
- Breast Lesions and Carcinomas
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Diagnosis and Treatment
- Radiation Therapy and Dosimetry
- Brain Metastases and Treatment
- MRI in cancer diagnosis
- Reconstructive Surgery and Microvascular Techniques
- Cancer Treatment and Pharmacology
- Cancer Diagnosis and Treatment
- Economic and Financial Impacts of Cancer
- Digital Imaging in Medicine
- Radiation Dose and Imaging
- Chemotherapy-induced cardiotoxicity and mitigation
- Head and Neck Cancer Studies
- Digital Radiography and Breast Imaging
- Advanced Breast Cancer Therapies
- Cancer Risks and Factors
- COVID-19 and healthcare impacts
- Cancer Genomics and Diagnostics
Royal Marsden NHS Foundation Trust
2015-2024
Royal Marsden Hospital
2011-2024
Institute of Cancer Research
2015-2024
Cancer Research UK
2020-2023
University College Cork
2022
National Health Service
2012-2021
Emory University
2021
Government of the United Kingdom
2021
Institute of Cancer Research
2018-2020
National Institute for Health Research
2020
Some observational studies suggest that the use of pulmonary-artery catheters to guide therapy is associated with increased mortality.
BackgroundWe aimed to identify a five-fraction schedule of adjuvant radiotherapy (radiation therapy) delivered in 1 week that is non-inferior terms local cancer control and as safe an international standard 15-fraction regimen after primary surgery for early breast cancer. Here, we present 5-year results the FAST-Forward trial.MethodsFAST-Forward multicentre, phase 3, randomised, non-inferiority trial done at 97 hospitals (47 centres 50 referring hospitals) UK. Patients aged least 18 years...
Critically ill patients who require mechanical ventilation are at increased risk for gastrointestinal bleeding from stress ulcers. There conflicting data on the effect of histamine H2-receptor antagonists and cytoprotective agent sucralfate rates bleeding, ventilator-associated pneumonia, mortality.
Local cancer relapse risk after breast conservation surgery followed by radiotherapy has fallen sharply in many countries, and is influenced patient age clinicopathological factors. We hypothesise that partial-breast restricted to the vicinity of original tumour women at lower than average local will improve balance beneficial versus adverse effects compared with whole-breast radiotherapy.
Purpose: MR-guided Radiation Therapy (MRgRT) allows for high-precision radiotherapy under real-time MR visualization. This enables margin reduction and subsequent dose escalation which may lead to higher tumor control less toxicity. The Unity MR-linac (Elekta AB, Stockholm, Sweden) integrates a linear accelerator with 1.5T diagnostic quality MRI an online adaptive workflow. A prospective international registry was established facilitate the evidence-based implementation of into clinical...
AimsRadiotherapy target volumes in early breast cancer treatment increasingly include the internal mammary chain (IMC). In order to maximise survival benefits of IMC radiotherapy, doses heart and lung should be minimised. This dosimetry study compared ability three-dimensional conformal arc therapy proton beam (PBT) techniques with without breath-hold achieve volume constraints while minimising dose organs at risk (OARs).Materials methodsIn 14 patients' datasets, seven radiotherapy were...
BackgroundRadiotherapy before mastectomy and autologous free-flap breast reconstruction can avoid adverse radiation effects on healthy donor tissues delays to adjuvant radiotherapy. However, evidence for this treatment sequence is sparse. We aimed explore the feasibility of preoperative radiotherapy followed by skin-sparing deep inferior epigastric perforator (DIEP) flap in patients with cancer requiring mastectomy.MethodsWe conducted a prospective, non-randomised, study at two National...
IMPORT LOW demonstrated noninferiority of partial-breast and reduced-dose radiotherapy versus whole-breast for local relapse similar or reduced toxicity at 5 years. Comprehensive patient-reported outcome measures collected serial time points are now reported.
The authors investigated aesthetic outcome and patient satisfaction in women who have undergone deep inferior epigastric artery perforator (DIEP) flap reconstruction the setting of postmastectomy radiotherapy. Patients underwent DIEP without radiotherapy were control group.