Youlia Kirova

ORCID: 0000-0002-1795-7509
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About
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Research Areas
  • Breast Cancer Treatment Studies
  • Advanced Radiotherapy Techniques
  • Breast Lesions and Carcinomas
  • Lymphoma Diagnosis and Treatment
  • Brain Metastases and Treatment
  • HER2/EGFR in Cancer Research
  • Breast Implant and Reconstruction
  • Cancer Treatment and Pharmacology
  • Lung Cancer Treatments and Mutations
  • Effects of Radiation Exposure
  • Radiation Therapy and Dosimetry
  • Glioma Diagnosis and Treatment
  • Cancer Diagnosis and Treatment
  • Lung Cancer Research Studies
  • CNS Lymphoma Diagnosis and Treatment
  • Sarcoma Diagnosis and Treatment
  • Chemotherapy-induced cardiotoxicity and mitigation
  • BRCA gene mutations in cancer
  • Vascular Tumors and Angiosarcomas
  • Nonmelanoma Skin Cancer Studies
  • Cancer Genomics and Diagnostics
  • Cancer and Skin Lesions
  • Lung Cancer Diagnosis and Treatment
  • Medical Imaging Techniques and Applications
  • Multiple and Secondary Primary Cancers

Institut Curie
2016-2025

Université de Versailles Saint-Quentin-en-Yvelines
2019-2024

Université Paris Sciences et Lettres
2018-2023

Centre Hospitalier de Saint-Quentin
2020-2023

Délégation Paris 6
2023

Université Paris-Saclay
2022

Radiation Oncology Associates
2012-2020

Yonsei University
2019

Institut Jules Bordet
2019

University Hospital of Geneva
2019

Sarcomas are a rare complication of radiotherapy for breast carcinoma and patients have poor prognosis. The incidence, histology, management with sarcomas were reviewed in the current study.The authors records 16,705 carcinoma. Of these, 13,472 (81%) treated megavoltage 3233 without at Institute Curie (Paris, France) between 1981 1997. Median doses 50-55 grays (Gy) 25-27 fractions delivered to whole over period 5-5.5 weeks (2 Gy/day, 5 weekly fractions) followed, when indicated, by 16-26-Gy...

10.1002/cncr.21223 article EN Cancer 2005-06-24

Prognostic factors of ipsilateral breast tumor recurrence (IBTR) may change over time following breast-conserving therapy.The EORTC "boost no boost" trial showed that young age and high-grade invasive carcinoma were the most important risk for IBTR. This study reanalyses pathological prognostic related to IBTR using long-term follow-up.Participants included 5569 early-stage cancer patients, treated with surgery (BCS) whole-breast irradiation (WBI), who randomized between boost a 16-Gy in...

10.1001/jamaoncol.2016.3031 article EN JAMA Oncology 2016-09-08

Abstract Background Cancer patients have been reported to be at higher risk of COVID-19 complications and deaths. We report the characteristics outcome diagnosed with during breast cancer treatment Institut Curie hospitals (ICH, Paris area, France). Methods An IRB-approved prospective registry was set up ICH on March 13, 2020, for all symptoms or radiologic signs. Registered data included patient history, tumor treatments, symptoms, radiological features, outcome. Data extraction done April...

10.1186/s13058-020-01293-8 article EN cc-by Breast Cancer Research 2020-05-27

BackgroundMonocentric cohorts suggested that radiation-induced CD8 T-lymphocyte apoptosis (RILA) can predict late toxicity after curative intent radiotherapy (RT). We assessed the role of RILA as a predictor breast fibrosis (bf+) adjuvant RT in prospective multicenter trial.MethodsA total 502 breast-cancer patients (pts) treated by conservative surgery and were recruited at ten centers. was before flow cytometry. Impact on bf+ (primary endpoint) or relapse using competing risk method....

10.1016/j.ebiom.2015.10.024 article EN cc-by-nc-nd EBioMedicine 2015-10-26

Objective: The aim of this study was to identify the comprehensive risk factors for lymphedema, thereby enabling a more informed multidisciplinary treatment decision-making. Summary Background Data: Lymphedema is serious long-term complication in breast cancer patients post-surgery; however, influence multimodal therapy on its occurrence remains unclear. Methods: We retrospectively collected treatment-related data from 5549 who underwent surgery between 2007 and 2015 at our institution....

10.1097/sla.0000000000003491 article EN Annals of Surgery 2019-07-23

Treatment for non-metastatic breast cancer (BC) may be the cause of second malignancies in long-term survivors. Our aim was to investigate whether survivors present a higher risk malignancy than general population according treatment received. We analysed data 16 705 BC treated at Curie Institute (1981-1997) by either chemotherapy (various regimens), radiotherapy (high-energy photons from 60Co unit or linear accelerator) and/or hormone therapy (2-5 years tamoxifen). calculated...

10.1038/sj.bjc.6604241 article EN cc-by-nc-sa British Journal of Cancer 2008-02-12

Abstract The aims of this study were to define the initial pathological and clinical characteristics, prognostic factors patients with primary breast malignant lymphoma (PBL). All treated at Institut Curie for involvement reviewed. A review all cases was performed. Forty‐five selected in whom 38 diffuse large B‐cell lymphoma. complete analysis then performed on these patients. Twenty out 28 (71%) Bcl‐2 positive four (14%) had a CD10 staining. Peculiar characteristics showed nodal 58% two or...

10.1002/ajh.21353 article EN American Journal of Hematology 2008-12-17

The use of a radiotherapy (RT) boost to the tumor bed after whole-breast RT (WBRT) for ductal carcinoma in situ (DCIS) is largely extrapolated from invasive cancer data, but robust evidence specific DCIS lacking.To compare ipsilateral breast recurrence (IBTR) women with treated vs without breast-conserving surgery and WBRT.This retrospective analysis pooled deidentified patient-level data 10 academic institutions United States, Canada, France January 1, 1980, through December 31, 2010. All...

10.1001/jamaoncol.2016.6948 article EN JAMA Oncology 2017-03-31
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