A5018733056- Stroke Rehabilitation and Recovery
- Lymphatic System and Diseases
- Nerve Injury and Rehabilitation
- Balance, Gait, and Falls Prevention
- Orthopedic Surgery and Rehabilitation
- Breast Cancer Treatment Studies
- Cerebral Palsy and Movement Disorders
- Peripheral Nerve Disorders
- Spinal Cord Injury Research
- Cardiac Health and Mental Health
- Myofascial pain diagnosis and treatment
- Therapeutic Uses of Natural Elements
- Cardiovascular and exercise physiology
- Dysphagia Assessment and Management
- Musculoskeletal pain and rehabilitation
- Family and Disability Support Research
- Osteoarthritis Treatment and Mechanisms
- Neurogenesis and neuroplasticity mechanisms
- Diagnosis and Treatment of Venous Diseases
- Infant Development and Preterm Care
- Traumatic Brain Injury Research
- Shoulder Injury and Treatment
- Cardiac Arrest and Resuscitation
- Vitamin D Research Studies
- Breast Implant and Reconstruction
Severance Hospital
2019-2024
Yonsei University
2007-2024
CHA University
2016-2021
Jeju National University Hospital
2009-2017
CHA Bundang Medical Center
2015-2017
Catholic Kwandong University
2011-2014
Sealaska Heritage Institute
2013
Myongji Hospital
2011-2012
Jeju National University
2009-2010
University of Cincinnati
1996
alpha-Melanocyte stimulating hormone (alpha-MSH) and ACTH increase the proliferation melanogenesis of cultured human melanocytes. To further analyze how melanotropins produce these biological effects, we investigated regulation melanocortin receptor MC1R expression by alpha-MSH using Northern blot analysis determine relative affinity for structurally similar peptides alpha-MSH, ACTH, beta-MSH, gamma-MSH. We also determined potencies hormones to stimulate cAMP formation, tyrosinase activity,...
Objective To investigate the effectiveness of commercial gaming-based virtual reality (VR) therapy on recovery paretic upper extremity in subacute stroke patients. Methods Twenty patients with first-onset were enrolled and randomly assigned to case group (n=10) control (n=10). Primary outcome was measured by limb score through Fugl-Meyer Assessment (FMA-UL) for motor function both extremities. Secondary outcomes assessed extremities including manual test (MFT), box block (BBT), grip...
Objective: The aim of this study was to identify the comprehensive risk factors for lymphedema, thereby enabling a more informed multidisciplinary treatment decision-making. Summary Background Data: Lymphedema is serious long-term complication in breast cancer patients post-surgery; however, influence multimodal therapy on its occurrence remains unclear. Methods: We retrospectively collected treatment-related data from 5549 who underwent surgery between 2007 and 2015 at our institution....
Purpose: To investigate the effects of music therapy on depressive mood and anxiety in post-stroke patients evaluate satisfaction levels caregivers.Materials Methods: Eighteen patients, within six months onset mini mental status examination score over 20, participated this study.Patients were divided into control groups.The experimental group program for four weeks.Psychological was evaluated with Beck Anxiety Inventory (BAI) Depression (BDI) before after therapy.Satisfaction by a...
Objective. The purpose of this study was to investigate the feasibility using real-time high-resolution sonography guide an injection needle into intra-articular space within knee. Methods. Eighty-nine patients with radiographically confirmed knee osteoarthritis (Kellgren-Lawrence grade 2 or 3) without effusion were included. After sonographically guided blind hyaluronic acid (HA) and contrast dye through a medial patellar portal (MPP) joint, radiographic image made ascertain whether...
Repetitive transcranial magnetic stimulation (rTMS) is used as a non-invasive treatment for various diseases, and its potential application in cancer has been proposed by researchers. However, the precise mechanisms effects of rTMS on many types cancer, including glioblastoma (GBM), remain largely unknown. This study aimed to investigate low-frequency vitro vivo GBM models elucidate an underlying biological mechanism GBM. In were treated with (0.5 Hz, 10 min per day), assessed using...
To compare quantitative muscle activation between erect and slouched sitting postures in the muscles around scapula, to investigate correlation angle of thoracic kyphosis alteration activity depending on two different postures.Ten healthy males participated study. Unilateral surface electromyography (SEMG) was performed for serratus anterior, middle trapezius (MT), lower (LT), which are scapular stabilizer muscles, as well latissimus dorsi. Participants elevated their shoulders 3 seconds up...
The aim of this study was to assess whether the effects a motorized aquatic treadmill exercise program improve isometric strength knee muscles, cardiorespiratory fitness, arterial stiffness, motor function, balance, functional outcomes, and quality life in subacute stroke patients.Thirty-two patients were randomly assigned 4-wk training sessions either therapy (n = 19) or land-based aerobic 18). Isometric measured using an isokinetic dynamometer. Cardiopulmonary fitness evaluated...
Objective: Brachial–ankle pulse wave velocity (baPWV) evaluates arterial stiffness and also predicts early outcome in stroke patients. The objectives of this study were to investigate subacute nonfunctional ambulatory patients compare the effects robot-assisted gait therapy (RAGT) combined with rehabilitation (RT) on functional recovery those RT alone. Method: RAGT group (N = 30) received 30 minutes conventional RT, control 26) 60 5 times a week for 4 weeks. baPWV was measured calculated...
Abstract Cervical and upper thoracic spinal cord injury causes impairments in respiratory muscle performance, leading to variable degrees of pulmonary dysfunction rendering deep breathing difficult for affected individuals. In this retrospective study, we investigated the effects self-directed training context by assessing function relative characteristics. A total 104 patients (tetraplegia/paraplegia; 65/39, acute/subacute/chronic; 14/42/48) were admitted short-term (4–8 weeks) in-patient...
Abstract Background and Objectives Indocyanine green (ICG) lymphography is the reference standard for evaluating lymphedema stage identifying lymphatic vessels. However, penetration depth was limited to 1–2 cm from skin surface. This prospective study compares clinical outcomes following lymphaticovenous anastomoses (LVA) in patients with upper lower limb using contrast‐enhanced ultrasonography (CEUS) ICG as a preoperative imaging modality. Methods Under general anesthesia, Sonazoid®...
To determine if assistive ergometer training can improve the functional ability and aerobic capacity of subacute stroke patients electrical stimulation (FES) paretic leg during cycling has additional effects.Sixteen patents were randomly assigned to FES group (n=8) or control (n=8). All underwent for 30 minutes (five times per week 4 weeks). The received lower limb muscles training. six-minute walk test (6MWT), Berg Balance Scale (BBS), Korean version Modified Barthel Index (K-MBI) evaluated...
Background: Cancer treatment-related lymphedema (CTRL) affects patients physically, psychologically and emotionally, remains a significant quality of life issue among with cancer. Reliable methods to measure changes in are required for early detection, acute intensive treatment, long-term management. Here, we evaluated the use bioimpedance analysis (BIA) as tool before after treatment. Patients Methods: CTRL who were admitted secondary university hospital between October 2017 July 2018...
PurposeTo develop and test a multivariable normal tissue complication probability (NTCP) model predicting lymphedema in patients with breast cancer receiving radiation therapy.Methods MaterialsWe retrospectively reviewed 1345 who received therapy from 2 independent institutions. The were divided into training cohort (institution A, n = 368, all treated 3-dimensional conformal external beam [RT] Gy/fraction) an validation B, 977, either RT or volumetric modulated 1.8-2.0 Gy/fraction 2.67...
Background: The present study aims to explore the effect of weight bearing exercise on bone mineral density (BMD) and growth in children with cerebral palsy (CP). Methods: Twelve CP functional level gross motor classification scale (GMFCS) V 6 healthy (control group) were included study. Participants underwent a dual-energy X-ray absorptiometry scan measure BMD femur full-length anteroposterior radiography length tibia at baseline after months. Patients randomly divided into 2 groups: group...
To assess the feasibility and safety of a 6-week course water walking performed using motorized aquatic treadmill in individuals with subacute stroke for cardiorespiratory fitness, endurance, activities daily living.Twenty patents were randomly assigned to exercise (ATE) or land-based (LBE). The ATE group (n = 10) water-based aerobic on treadmill, LBE cycle ergometer. Both groups 30 minutes, 5 times per week 6 weeks. Primary outcome measures 6-minute walk test endurance cardiopulmonary...
Objective To identify the potential predictors of ambulatory function in subacute stroke patients, and to determine contributing factors according gait severity. Methods Fifty-three patents were enrolled. Ambulatory was assessed by speed endurance. Balance evaluated Berg Scale score (BBS) Timed Up Go test (TUG). The isometric muscular strengths bilateral knee extensors flexors measured using an isokinetic dynamometer. Cardiovascular fitness expired gas analyzer. Participants assigned into...
Lower extremity lymphedema (LEL) is a well-known adverse effect related to cervical and endometrial cancer (CEC); however, very few studies have elucidated the clinicopathologic risk factors LEL. We investigated incidence in patients who received primary surgery and/or adjuvant radiotherapy (RT) or chemotherapy for CEC.We retrospectively reviewed 2,565 underwent following CEC diagnosis between January 2007 December 2020. LEL was based on objective subjective assessments by experts....
We investigated the effects of environmental enrichment (EE) on function transplanted adipose stem cells (ASCs) and combined effect EE ASC transplantation neurobehavioral in an animal model chronic hypoxic-ischemic (HI) brain injury. HI damage was induced 7-day-old mice by unilateral carotid artery ligation exposure to hypoxia (8% O2 for 90 min). At 6 weeks age, were randomly injected with either ASCs or PBS into striatum assigned standard cages (SC), comprising ASC-EE (n=18), ASC-SC (n=19),...
To investigate the serum vitamin D level and its determinant factors in stroke patients.Fifty-one patients who had documented of 25-hydroxyvitamin D(25(OH)D) were included. Patients divided into subacute (n=23) chronic groups (n=28). The mean levels 25(OH)D two compared. Correlations between each post-stroke duration also analyzed. assess other possible influencing factors, subdivided by ambulation ability feeding methods for comparison level.The was significantly lower group than (12.3 vs....