A5019917193- Cerebral Palsy and Movement Disorders
- Diverse Approaches in Healthcare and Education Studies
- Botulinum Toxin and Related Neurological Disorders
- Health and Wellbeing Research
- Educational Systems and Policies
- Psychosocial Factors Impacting Youth
- Nutrition, Health and Food Behavior
- Healthcare Education and Workforce Issues
- Family and Disability Support Research
- Education and Learning Interventions
- Stroke Rehabilitation and Recovery
- Neonatal and fetal brain pathology
- Consumer Perception and Purchasing Behavior
- Infant Development and Preterm Care
- Diverse Topics in Contemporary Research
- Food Quality and Safety Studies
- Pediatric health and respiratory diseases
- Education, Safety, and Science Studies
- Korean Urban and Social Studies
- Cultural and Historical Studies
- Educational Research and Pedagogy
- Neurological disorders and treatments
- Asian Culture and Media Studies
- Energy and Environmental Systems
- Advanced Neuroimaging Techniques and Applications
Yonsei University
2014-2023
Severance Hospital
2004-2022
Icahn School of Medicine at Mount Sinai
2015-2022
Korea University
2005-2017
Korea Electric Power Corporation (South Korea)
2010-2013
CHA University
2012
Dongguk University
2007-2012
Korea Hydro and Nuclear Power (Korea)
2010
Ewha Womans University Medical Center
2010
Bridge University
2009
The input enhancement hypothesis proposed by Sharwood Smith (1991, 1993) has stimulated considerable research over the last 15 years. This article reviews on textual of (TE), an area where majority studies have aggregated. Methodological idiosyncrasies are norm this body research. Seven major issues appear to be limiting generalizability findings and holding up further progress in understanding efficacy TE for learning: (1) noticing and/or acquisition; (2) comprehension; (3) simultaneous or...
Periventricular leucomalacia has long been investigated as a leading cause of motor and cognitive dysfunction in patients with spastic diplegic cerebral palsy. However, periventricular on conventional magnetic resonance imaging do not always have preterm children without neurological abnormalities may leucomalacia. In addition, it is uncertain whether descending tract or overlying cortical injury related to impairment. To investigate the relationship between pathway impairment, we conducted...
The purpose of our study was to investigate the effects hippotherapy on gross motor function and functional performance in children with spastic cerebral palsy (CP).We recruited 34 (M:F=15:19, age: 3-12 years) CP who underwent for 45 minutes twice a week 8 weeks. Twenty-one were control group. distribution classification system level mean age not significantly different between two groups. Outcome measures, including Gross Motor Function Measure (GMFM)-66, GMFM-88 Pediatric Evaluation...
Limitations of current viral-based gene therapies for malignant tumors include lack cancer-specific targeting and insufficient tumor delivery. To ameliorate these problems develop a truly effective adenovirus gene-based therapy cancer, we constructed conditionally replication competent (CRCA) manifesting the unique properties tumor-specific virus in combination with production cancer-selective cytotoxic cytokine, melanoma differentiation associated gene-7/interleukin-24 ( mda -7/IL-24),...
Abstract Background Several experimental studies in stroke patients suggest that mirror therapy and various virtual reality programs facilitate motor rehabilitation. However, the underlying mechanisms for these therapeutic effects have not been previously described. Objectives We attempted to delineate changes corticospinal excitability when individuals were asked exercise their upper extremity using a real mirror. Moreover, we role of visual modulation within environment affected healthy...
Aim To investigate the efficacy of a virtual reality rehabilitation system wearable multi‐inertial sensors to improve upper‐limb function in children with brain injury. Method Eighty (39 males, 41 females) injury including cerebral palsy aged 3 16 years (mean age 5y 8mo, SD 2y 10mo) were assessed as part multicentre, single‐blind, randomized controlled trial. The intervention group received 30‐minute and session conventional occupational therapy while control 60 minutes per session, 20...
Objectives: To investigate the effects of rhythmic auditory stimulation (RAS) on gait patterns in comparison with changes after neurodevelopmental treatment (NDT/Bobath) adults cerebral palsy. Design: A repeated-measures analysis between pretreatment and posttreatment tests a study groups. Setting: Human laboratory. Subjects: Twenty-eight palsy patients bilateral spasticity participated this study. The subjects were randomly allocated to either ( n = 13) or 15). Interventions: Gait training...
The aim of this article is to elucidate the ideal sites for botulinum toxin injection by examining intramuscular nerve distributions in hamstring muscles. muscles, biceps femoris, semitendinosus, and semimembranosus (10 specimens each) were stained modified Sihler method. locations muscle origins, entry points, arborized areas recorded as percentages total distance from line crossing medial lateral tibial condyles (0%) ischial tuberosity (100%). Intramuscular arborization patterns observed...
ABSTRACT Fibrillin-1, the main component of 10-12 nm microfibrils extracellular matrix, is synthesized as profibrillin and proteolytically processed to fibrillin. The putative cleavage site has been mapped carboxy-terminal domain profibrillin-1, between amino acids arginine 2731 serine 2732, by a spontaneous mutation in this recognition that prevents conversion. This contains basic acid sequence (R-G-R-K-R-R) for proprotein convertases furin/PACE family. In study, we use mini-profibrillin...
Congenital contractural arachnodactyly (CCA) is an autosomal dominant condition phenotypically related to Marfan syndrome (MFS). CCA caused by mutations in FBN2, whereas MFS results from FBN1. FBN2 mRNA extracted 12 unrelated patient cell strains was screened for mutations, and were identified six of these samples. All the cluster a limited region gene, where FBN1 produce severe, congenital form (so-called neonatal MFS). Furthermore, three occur locations exactly corresponding that have been...
Purpose: To identify the characteristics of static standing balance and its postural control mechanisms during quiet side-by-side changes in these measures whilst wearing hinged ankle-foot orthoses (AFOs) children with bilateral spastic cerebral palsy (CP).Materials Methods: Twenty-one CP (6.10 ± 1.09 year-old) 22 typically developing (TD) (5.64 0.49 were recruited.Pressure data recorded while subjects or without AFOs stood on dual force platforms net body center pressure (CoP) coordinates...
Background. Housing animals in an enriched environment (EE) enhances behavioral function. However, the mechanism underlying this EE-mediated functional improvement and resultant changes gene expression have yet to be elucidated. Objectives. We attempted investigate mechanisms associated with long-term exposure EE by evaluating patterns. Methods. housed 6-week-old CD-1 (ICR) mice standard cages or comprising a running wheel, novel objects, social interaction for 2 months. Motor cognitive...
Purpose:The aim of this study was to investigate the effect incentive spirometer exercise (ISE) on pulmonary function and maximal phonation time (MPT) in children with spastic cerebral palsy (CP).Materials Methods: Fifty CP were randomly assigned two groups: experimental group control group.Both groups underwent comprehensive rehabilitation therapy.The additional ISE.The forced vital capacity (FVC), expiratory volume at one second (FEV1), FEV1/FVC ratio, peak flow (PEF), MPT assessed as...
This study was designed to determine the effectiveness of electrical stimulation over trunk in improving sitting balance young children with spastic diplegic cerebral palsy who displayed poor control. The subjects ranged age from 8 16 months and were randomly assigned two groups. Both group had physical therapy for 6 weeks. Electrical (ES) additional abdomen posterior back muscles. Radiographic studies carried out on whole spine while they before after treatment. Kyphotic angle, Cobb's angle...