A5019892854- Gastrointestinal motility and disorders
- Cancer survivorship and care
- Colorectal Cancer Screening and Detection
- Mental Health and Patient Involvement
- Complementary and Alternative Medicine Studies
- Patient-Provider Communication in Healthcare
- Palliative Care and End-of-Life Issues
- Pathogenesis and Treatment of Hiccups
- Helicobacter pylori-related gastroenterology studies
- Global Cancer Incidence and Screening
- Microscopic Colitis
- Music Therapy and Health
- Economic and Financial Impacts of Cancer
- Gastric Cancer Management and Outcomes
- Folate and B Vitamins Research
- Patient Satisfaction in Healthcare
- Child Nutrition and Feeding Issues
- Celiac Disease Research and Management
- Congenital gastrointestinal and neural anomalies
- Medication Adherence and Compliance
- Diet and metabolism studies
- Library Collection Development and Digital Resources
- Advances in Oncology and Radiotherapy
- Therapeutic Uses of Natural Elements
- Intestinal and Peritoneal Adhesions
The Patients Association
2014-2024
Rome Foundation
2024
St James's University Hospital
2018-2022
IQVIA (United States)
2022
University of North Carolina at Chapel Hill
2007-2018
University of Leeds
2018
National Cancer Research Institute
2010-2018
University of Colorado Denver
2018
Dartmouth College
2016-2017
University of Colorado Anschutz Medical Campus
2016
BackgroundWe aimed to identify a five-fraction schedule of adjuvant radiotherapy (radiation therapy) delivered in 1 week that is non-inferior terms local cancer control and as safe an international standard 15-fraction regimen after primary surgery for early breast cancer. Here, we present 5-year results the FAST-Forward trial.MethodsFAST-Forward multicentre, phase 3, randomised, non-inferiority trial done at 97 hospitals (47 centres 50 referring hospitals) UK. Patients aged least 18 years...
<h3>Abstract</h3> <b>Objectives:</b> To determine whether preoperative optimisation of oxygen delivery improves outcome after major elective surgery, and to the inotropes, adrenaline dopexamine, used enhance influence outcome. <b>Design:</b> Randomised controlled trial with double blinding between inotrope groups. <b>Setting:</b>York District Hospital, England. <b>Subjects:</b>138 patients undergoing surgery who were at risk developing postoperative complications either because or presence...
Electronic patient self-Reporting of Adverse-events: Patient Information and aDvice (eRAPID) is an online eHealth system for patients to self-report symptoms during cancer treatment. It provides automated severity-dependent advice guiding self-management or medical contact displays the reports in electronic records. This trial evaluated impact eRAPID on symptom control, healthcare use, self-efficacy, quality life (QOL) a population treated predominantly with curative intent.Patients...
Although clinicians generally make treatment decisions in irritable bowel syndrome (IBS) related to the type of symptoms, other factors such as perceived severity and risks patients are willing tolerate for effective also important consider. These not fully understood.To describe among with IBS their symptoms severity, quality life health status, medications taken, risk that they would take continue optimal relief.Adult diagnosed who accessed websites International Foundation Functional GI...
Patient education improves clinical outcomes in patients with chronic illness, but little is known about the needs of IBS. OBJECTIVES The objective this study was to identify: (1) perceptions IBS; (2) content areas where feel insufficiently informed, i.e., “knowledge gaps” diagnosis, treatment options, etiology, triggers, prognosis, and role stress; (3) whether there are differences related items 1 2 among clinically significant subgroups. METHODS IBS-Patient Education Questionnaire...
Aliment Pharmacol Ther 31 , 666–675 Summary Background Previous studies on coeliac disease (CD)‐related quality of life (QOL) have been limited by their use a ‘generic’ rather than disease‐specific assessment instruments. Aim To develop and psychometrically validate new instrument, the CD‐QOL. Methods Through series focus groups, we elicited items from patients that related to specific nature its impact basic needs. expert review, cognitive debriefing with pilot testing, scale was developed,...
Adherence to adjuvant endocrine therapy (AET) following breast cancer is known be suboptimal despite its efficacy in reducing recurrence and mortality. This study aims investigate factors associated with non-adherence inform the development of interventions support women promote adherence. A questionnaire survey measure level adherence, side effects experienced, beliefs about medicine, received socio-demographic details was sent 292 2–4 years post diagnosis. Differences between non-adherers...
The relations between mild cognitive impairment without dementia (MCI/CIND) and everyday functional abilities were examined using data from the Canadian Study of Health Aging (CSHA). Individuals identified with MCI/CIND if both caregiver report clinician judgment agreed on presence in absence dementia. Cross-sectional longitudinal comparisons indicated that individuals demonstrated a broad range instrumental activities daily living (IADL) compared to no (NCI). In cross-sectional analyses,...
Assessing health related quality of life (HRQOL) is becoming more important in research and clinical care. However, little information available on the performance HRQOL questionnaires for functional bowel disorders (FBD). The aims this study were to (a) understand Sickness Impact Profile (SIP) IBS-QOL at baseline after treatment, (b) determine which subscales best improve with (c) clinically meaningful improvement, (d) predictors response treatment.Women moderate severe FBD evaluated using...
Abstract A controlled evaluation of a single-layer everting technique suture versus conventional two-layer inverting has been attempted in clinical large-bowel surgery. Thirty-five patients suffering from carcinoma or other diseases the large intestine were allocated randomly to each conduct various forms colonic resection with anastomosis closure transverse colostomy. There 3 operative deaths after and 1 suture, all attributable mainly anastomotic failure. higher proportion developed wound...
Cancer-related fatigue (CRF) is a frequent and distressing symptom experienced after cancer treatment. RESTORE the first web-based resource designed to enhance self-efficacy manage CRF following curative-intent The aim of this study test proof concept inform design an effectiveness trial. A multi-centre parallel-group two-armed (1:1) exploratory randomised controlled trial (RCT) with qualitative process evaluation was employed in study. Participants (≥18 years; ≤5 years post treatment...
OBJECTIVES: The digital rectal examination (DRE) may be underutilized. We assessed the frequency of DREs among a variety providers and explored factors affecting its performance utilization. METHODS: A total 652 faculty, fellows, medical residents, final-year students completed questionnaire about their use DREs. RESULTS: On average, 41 per year were performed. yearly number examinations was associated with years experience specialty type. Patient refusal rates lowest gastroenterology (GI)...
OBFECTIVES: Narcotic bowel syndrome (NBS) is characterized by a paradoxical increase in abdominal pain associated with continued or escalating dosages of narcotics. This study evaluated the clinical and psychosocial features patients NBS response to detoxification treatment. METHODS: For 2 years, 39 seen GI consult service at University North Carolina Chapel Hill (UNC) presumed were placed on program. Clinical, psychosocial, health status, outcome data obtained before after detoxification....
eRAPID (electronic patient self-Reporting of Adverse-events: Patient Information and aDvice) is an internet based system for patients to self-report symptoms side effects (adverse events or AE) cancer treatments. allows AE reporting from home reported data accessible via Electronic Records (EPR) use in routine care. The can generate alerts clinical teams severe provides advice on managing mild AEs. overall aims are improve the safe delivery treatments, enhance care standardise...
Introduction: Despite evidence of the efficacy adjuvant endocrine therapy (AET) in reducing risk recurrence and mortality after treatment for primary breast cancer, adherence to AET is suboptimal. This study aimed explore factors that influence nonadherence following cancer inform development supportive interventions. Methods: Interviews were conducted with 32 women who had been prescribed AET, 2–4 years their diagnosis cancer. Both adherers (n=19) nonadherers (n=13) recruited. The analysis...
Summary Background The Rome Foundation Global Epidemiology Study (RFGES) found that 40.3% of adults in 26 internet‐surveyed countries met IV criteria for disorders gut–brain interaction (DGBI). However, additional people not meeting DGBI may also be burdened by frequent gastrointestinal symptoms. Aims To explore the prevalence and demographic distribution sub‐diagnostic symptoms, hypothesised associated effects on quality life (QoL), functioning healthcare needs. Methods We analysed data...
The implications of the Rome III recommendations to change irritable bowel syndrome (IBS) subtype criteria for stool pattern are unknown.(1) Determine level agreement between II and subtypes (2) compare behaviors over time.Female patients (n=148) with defined IBS were prospectively tracked 5 consecutive 3-month periods. At baseline, habit reports on questionnaires used subclassify into subtypes. Over subsequent 15 months, diary cards based previously derived surrogate subtypes.The...
Background Service user involvement is embedded in the United Kingdom's National Health Service, but knowledge about impact of on service users, such as benefits and challenges involvement, scant. Our research addresses this gap. Objective To explore personal lives users affected by cancer. Design We conducted eight focus groups with supplemented nine face-to-face interviews involved individuals active at a local, regional national level. Thematic analysis was both independently...
Background: Support and evidence for patient, unpaid caregiver public involvement in research (user involvement) are growing. Consensus on how best to involve users palliative care is lacking. Aim: To determine an optimal user-involvement model research. Design: We hosted a consultation workshop using expert presentations, discussion nominal group technique generate recommendations consensus agreement of importance. A total 35 32 researchers were approached attend the workshop, which...