A5054047124- Reconstructive Surgery and Microvascular Techniques
- Breast Implant and Reconstruction
- Breast Cancer Treatment Studies
- Bone fractures and treatments
- Reconstructive Facial Surgery Techniques
- Wound Healing and Treatments
- Cancer Diagnosis and Treatment
- Surgical Sutures and Adhesives
- Electrospun Nanofibers in Biomedical Applications
- Cancer survivorship and care
- SARS-CoV-2 and COVID-19 Research
- Venous Thromboembolism Diagnosis and Management
- Blood properties and coagulation
- Anatomy and Medical Technology
- 3D Printing in Biomedical Research
- Spinal Fractures and Fixation Techniques
- Head and Neck Cancer Studies
- Heparin-Induced Thrombocytopenia and Thrombosis
- COVID-19 and healthcare impacts
- Diabetes Management and Research
- Multiple Myeloma Research and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Digital Imaging in Medicine
- Trauma Management and Diagnosis
- Tracheal and airway disorders
Royal Marsden Hospital
2008-2024
Royal Marsden NHS Foundation Trust
2011-2022
Princess Royal University Hospital
2021-2022
Government of the United Kingdom
2021
Sutton Hospital
2018
University of Brighton
2015
King's College London
2014
St Thomas' Hospital
2014
King's College Hospital
2014
Pinsent Masons (United Kingdom)
2009
BackgroundRadiotherapy before mastectomy and autologous free-flap breast reconstruction can avoid adverse radiation effects on healthy donor tissues delays to adjuvant radiotherapy. However, evidence for this treatment sequence is sparse. We aimed explore the feasibility of preoperative radiotherapy followed by skin-sparing deep inferior epigastric perforator (DIEP) flap in patients with cancer requiring mastectomy.MethodsWe conducted a prospective, non-randomised, study at two National...
The authors investigated aesthetic outcome and patient satisfaction in women who have undergone deep inferior epigastric artery perforator (DIEP) flap reconstruction the setting of postmastectomy radiotherapy. Patients underwent DIEP without radiotherapy were control group.
Abstract: This study investigated changes in the protein expression of purinergic receptors regenerating rat epidermis during normal wound healing, denervated wounds, and wounds treated with nerve growth factor (NGF), where healing rates are normalized. Excisional were placed within denervated, pedicled, oblique, groin skin flaps, contralateral abdomen to act as a control site. Six rats had NGF‐treated six untreated wounds. Tissue was harvested at day four after wounding. The...
Background: Primary and secondary rhinoplasty often requires multiple cartilage grafts. Polydioxanone foil may be used as a temporary biomechanical scaffold on which routinely discarded fragments can assembled to make maximal use of harvested material. Methods: The authors performed an outcome analysis 58 primary rhinoplasties in polydioxanone was combination with autologous for aesthetic valvular reconstruction the nose. Graft performance, complications, technical points are reported....
The number of women with stage IV disease who have breast reconstruction is small. primary aim this study was to examine opinions as the appropriateness in group. Association Breast Surgeons (ABS) and British Plastic Reconstructive Aesthetic (BAPRAS) were invited take part an online survey. Of respondents, 78.7% would operate on tumour. surgeons showed a propensity for immediate compared their surgery colleagues, 26.3% not offer at all. Immediate latissimus dorsi (LD) flap implant favoured...
For slim patients eligible to breast reconstruction, clinical concerns exist on availability of adequate amount donor tissue restore volume and challenges in donor-site closure, when using the deep inferior epigastric perforator (DIEP) flap. The purpose current study is analyze whether DIEP flap can provide for reconstruction patients, without increased complication rates or prolonged hospital stay.All receiving a unilateral at center 2007-2010 were included (n = 171). analyzed subgroups...
Abstract Background Slim women are not always considered candidates for bilateral autologous breast reconstruction. The study aims to assess the volume considerations and complications of deep inferior epigastric perforator (DIEP) flap in reconstruction among slim patients. Methods All patients undergoing DIEP at Royal Marsden Hospital, London, September 2007‐March 2015, were reviewed. Flap weight was compared mastectomy (weight ratio) recorded. Subgroup analyses according Body Mass Index...
Rosai-Dorfman disease (RDD), or sinus histiocytosis with massive lymphadenopathy, is a benign idiopathic histiocytic proliferation disorder.Cutaneous RDD (CRDD) rare entity that manifests solely skin papules nodules and does not present the usual constellation of symptoms classical RDD.Since 1990, fewer than 100 cases CRDD have been reported in English literature, majority patients being identified as middle-aged white women (Frater JL, Maddox JS, Obadiah JM, Hurley MY.Cutaneous disease:...
Abstract Background: The need for post mastectomy radiotherapy (PMRT), may preclude reconstructive surgeons from offering patients immediate, autologous reconstruction. This is due to historical evidence suggesting high rates of short- and long-term complications as well poorer aesthetic outcomes. As the indications PMRT broaden this practice denies an ever-increasing number women benefit immediate Aim: pilot study evaluates safety prior DIEP flap Methods: Women planned neoadjuvant...
IntroductionEvaluation of aesthetics after breast reconstruction is challenging. In the absence an objective measurement, panel assessment widely adopted. Heterogeneity scales and poor internal consistency make comparison difficult. Development validation expert scale using a Delphi consensus process described. It was designed specifically for use as gold standard development evaluation tool 3-Dimensional Surface Imaging (3D-SI).Materials methods20 items relating to aesthetic were identified...
Cytapheresis is an extracorporeal separation technique widely used in medicine for elimination of specific classes blood cells from circulating blood. It has been shown recently to have clinical efficacy various disease states, such as leukaemia, autoimmune disorders, rheumatoid arthritis, renal allograft rejection and sickle–cell anaemia. The current study was undertaken produce affinity-binding column, based upon a macroporous monolithic cryogel with structure interconnected pores, pore...