A5084123290- Renal cell carcinoma treatment
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Economic and Financial Impacts of Cancer
- Bladder and Urothelial Cancer Treatments
- Cancer Immunotherapy and Biomarkers
- Genetic factors in colorectal cancer
- Renal and related cancers
- COVID-19 and healthcare impacts
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Bone and Dental Protein Studies
- Radiopharmaceutical Chemistry and Applications
- Pediatric Urology and Nephrology Studies
- Gastric Cancer Management and Outcomes
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Oral and Maxillofacial Pathology
- Estrogen and related hormone effects
- dental development and anomalies
- Urinary Bladder and Prostate Research
- Multiple and Secondary Primary Cancers
- Ureteral procedures and complications
- Hormonal and reproductive studies
- Healthcare cost, quality, practices
- Cancer Diagnosis and Treatment
Central Clinical Hospital and Polyclinic
2020-2025
Botkin Hospital
2021
City Clinical Hospital
2021
P.A. Hertzen Moscow Oncology Research Institute
2012
Ministry of Health of the Russian Federation
2012
536 Background: Some patients with primary renal cell carcinoma (RCC) are not candidates for surgery or nephron-sparing interventions due to various factors, such as the presence of a functional single kidney central, high-complexity tumor. This study aimed evaluate whether combination nivolumab and ipilimumab could eliminate tumor in T1aN0M0 RCC. Methods: prospective, multicenter, phase 2 pilot enrolled biopsy-confirmed clear-cell RCC (cT1a) ≤4 cm, no metastases, who were ineligible...
Clinical Practice Points•One-half of patients with renal cell carcinoma infected severe acute respiratory syndrome coronavirus 2 required hospitalization.•Eastern Cooperative Oncology Group performance status could be negatively changed in these patients.•The mortality rate is higher than people without cancer.•Some have progression during infection. •One-half
Abstract Background To our knowledge, there is no clinical data pertaining to COVID-19 outcomes and safety of vaccination in Russian patients with genitourinary (GU) malignancies. Aim analysis was describe the characteristics infection course as well preliminary efficacy Gam-COVID-Vac vaccine active GU Methods Patients were retrospectively identified at nine cancer centers different regions. included if diagnosed by a polymerase chain reaction. Data from additional cancers who had positive...
Hormone therapy of metastatic prostate cancer (mPC) has been the “golden standard” treatment since 1941. However, survival rates in patients with this pathology have remained low. Based on results newer studies, early start docetaxel chemotherapy or antiandrogen abiraterone combination standard hormone allows to significantly increase mPC. In review, data from these studies and advisability at 1st line mPC are discussed.
Abstract Background: Some patients with primary renal cell carcinoma (RCC) are unable to have surgery for different reasons (functional single kidney a central, high-complexity RCC, high risk of nephrectomy and dialysis, complex coagulation disorders, etc.). We hypothesize that combination nivolumab ipilimumab could eliminate the tumor in T1aN0M0 ineligible surgical treatment. Methods: This is prospective, multicenter, non-randomized phase 2 pilot study. Patients biopsy-proven clear-cell RCC...
The study objective is to evaluate effectiveness and tolerability of 1st line combination immuno-oncological therapy with nivolumab ipilimumab in patients metastatic renal cell carcinoma (mRCC) clinical practice. Materials methods. included 38 mRCC who received immunotherapy between July 2019 September 2021. Median follow-up duration was 8 (2-25) months. Mean age the 58.3 (20-85) years. Previously 22 (57.9 %) underwent surgical treatment. Unfavorable physical status 2-3 per ECOG scale...
Hormone therapy is a basic treatment for locally advanced and/or metastatic prostate cancer (PC); however, most patients become resistant to first-line in the course of time. Abiraterone highly active, selective, irreversible CYP17 inhibitor that prevents conversion pregnenolone dehydroepiandrostenedione and progesterone androstenedione testes adrenals, as well directly tumor tissue. This drug able considerably improve tumor-specific overall survival rates with castration-resistant PC (CRPC)...
The wide use of current diagnostic techniques, such as ultrasound study, computed tomography, and magnetic resonance imaging, has led to significantly increased detection rates for disease in its early stages. This gave rise a change the standards treatment locally advanced renal cell carcinoma (RCC). Laparoscopic nephrectomy (LN) recently become standard RCC clinics having much experience with laparoscopic surgery. chief drawback LN is difficulties maintaining intraoperative hemostasis need...
The concurrence of gastric cancer and primary hepatic neoplasm ranks third in the structure polyneoplasia associated with accounts for 14.3%. Gastric tubular adenocarcinoma hepatocellular carcinoma are predominant histological forms. In practice, focal mass detected is generally interpreted as metastatic lesion, which frequently leads to unfounded refusal radical treatment. At same time, adequate preoperative examination obligatory verification both a tumor comparison their morphological...