A5007990735- Bladder and Urothelial Cancer Treatments
- Prostate Cancer Treatment and Research
- Urinary and Genital Oncology Studies
- Renal cell carcinoma treatment
- Prostate Cancer Diagnosis and Treatment
- Multiple and Secondary Primary Cancers
- Renal and related cancers
- PARP inhibition in cancer therapy
- DNA Repair Mechanisms
- Urologic and reproductive health conditions
- Pediatric Urology and Nephrology Studies
- Anesthesia and Pain Management
- Photodynamic Therapy Research Studies
- Cancer Immunotherapy and Biomarkers
- Testicular diseases and treatments
- Nausea and vomiting management
- Pain Management and Opioid Use
- Renal and Vascular Pathologies
- Genital Health and Disease
- RNA modifications and cancer
- Chemical synthesis and pharmacological studies
- Infectious Disease Case Reports and Treatments
- Digestive system and related health
- Radiopharmaceutical Chemistry and Applications
- Fibroblast Growth Factor Research
Ministry of Health of the Russian Federation
2021-2022
Medical Radiological Research Center
2021-2022
P.A. Hertzen Moscow Oncology Research Institute
2018-2021
Purpose: Our study aimed to assess whether the type of regional anesthesia influenced incidence chronic postthoracotomy pain syndrome (CPTPS).
In recent years, the treatment of acute pain syndrome has been considered as an independent direction in anesthesiology and intensive care. New schemes postoperative analgesia new drugs developed by pharmacologists are actively being introduced. One newer regimens for relief is patient-controlled (CPA) or on-demand analgesia. The development concept fast track surgery, one most widely discussed areas innovative technologies modern from point view anesthesiologist resuscitation specialist,...
A system of clinical and morphological criteria is currently used to determine the pattern superficial bladder cancer (SBC). However, this does not completely reflect potential SBC needs additional markers. The purpose study was search for evaluate molecular genetic disorders as markers course SBC. diagnostic panel included deletion loci 3р14, 9р21, 9q34, 17р13 (ТР53), mutations exon 7 FGFR3 gene, hypermethylation promoter regions RASSF1, RARB, p16, p14, CDH1 genes. made on 108 matched...
Prostate cancer (PC) is one of the most common male diseases. Pelvic lymphadenectomy (PLAE) an important diagnostic stage during both surgery and radiotherapy. The main goal PLAE to evaluate pelvic lymph nodes (LN), which makes it possible define prognosis disease choose rational treatment policy. paper analyzes results treating 298 moderate-to highrisk circumscribed locally advanced PC patients undergoing prostatectomy or extended at Department Oncourology, P.A. Herzen Moscow Oncology...
Background. Prostate cancer is one of the most common malignant tumors in men. Tailored treatment approaches to metastatic castration-resistant prostate based on identification specific biomarkers have been introduced only recently. So far, Food and Drug Administration has approved two drugs (olaparib rucaparib) targeting DNA repair genes. Aim. To assess frequency mutations genes Russian population. Materials methods. The article uses data from centers (National Medical Research Radiological...
The incidence of mesenchymal bladder tumors is 1—5 %; them, 0.43 % are leiomyomas. choice treatment strategy primarily depends on the size and location tumor. Small endovesical leiomyomas can be removed by transurethral resection bladder, while in case large (>5 cm) intramural or extravesical leiomyomas, laparoscopic more effective. In this article, we report a (>7 leiomyoma 28-year-old female patient. patient has undergone at P.A. Herzen Moscow Oncology Research Institute.
The study objective is to evaluate effectiveness and tolerability of 1st line combination immuno-oncological therapy with nivolumab ipilimumab in patients metastatic renal cell carcinoma (mRCC) clinical practice. Materials methods. included 38 mRCC who received immunotherapy between July 2019 September 2021. Median follow-up duration was 8 (2-25) months. Mean age the 58.3 (20-85) years. Previously 22 (57.9 %) underwent surgical treatment. Unfavorable physical status 2-3 per ECOG scale...
Renal cell carcinoma (RCC) is one of the most urgent topics in modern oncourology. This attributable to high morbidity and mortality rates associated with this pathology. dystopia a rather rare developmental anomaly. The literature data describing cases diagnosis treatment patients dystopic kidney malignancies are scarce. Moreover, if tumor present solitary kidney, it often extremely difficult perform an organ-saving operation for number features anatomic structure its vascular...
Notwithstanding the fact that BCG vaccine therapy is considered to be most effective method treat and prevent non-muscle invasive bladder cancer recurrences, maintenance performed insufficiently often. Whether long-term courses of intravesicular installations are needed obtain optimal results remains unsolved so far.
Prostate cancer (PC) is one of the most actual problems modern oncourology. Hormone therapy (HT) using medical castration main method treatment patients with metastatic PC. HT usage new class drugs that block receptors for luteinizing hormone releasing (LHRH) a promising and effective has number significant advantages over use analogues LHRH. This article presents review studies compared effectiveness side effects antagonists
The introduction of a method for molecular genetic analysis into clinical practice extends the possibilities diagnosing bladder cancer in its early stage. paper gives results urine cytological and cytogenetic investigations patients with cancer. Forty-four examinations 25 ones were made. both techniques diagnosis urothelial carcinoma coincided 12 cases. However, was verified only by 2
A retrospective analysis of medical records 581 patients with non-muscle-invasive bladder cancer was carried out. Out these patients, there were 467 men and 114 women, a male-to-female ratio 4:1. Among males, the highest incidence occurred in age range 45–59 year followed by groups 60‑74 18‑44 years, representing 45.8 %, 33.4 16 respectively. For females, rate observed 60 to 74 group (58.7 %). Women aged 45‑59 75‑90 years represented 26.5 % 14.3 The proportion women 45‑49 almost half this...
Bladder cancer is one of the most common malignant diseases involving urinary system. Accurate prediction disease course and outcome crucial for choosing an appropriate treatment strategy in these patients. Currently, there are several prognostic models predicting non-muscle invasive bladder outcomes. The scoring systems developed by European Organization Research Treatment Cancer (EORTC) Spanish Urological Club Oncological (CUETO) widely used cancer. Despite undeniable merits scales, they...
Among malignant neoplasms, kidney cancer occupies one of the first places in terms growth rate incidence Russia. Despite possibilities modern diagnostic research methods, number patients with common forms disease does not decrease. In 5–10% cases, renal cell carcinoma is complicated by formation a tumor clot inferior Vena cava (VCI), which requires volume surgery — nephrectomy thrombectomy, only effective treatment option for this group patients. Previously, results locally advanced were...