A5004623017- Breast Cancer Treatment Studies
- Head and Neck Cancer Studies
- Cancer Genomics and Diagnostics
- Head and Neck Surgical Oncology
- BRCA gene mutations in cancer
- Lung Cancer Treatments and Mutations
- HER2/EGFR in Cancer Research
- Lung Cancer Research Studies
- Breast Lesions and Carcinomas
- Advanced Breast Cancer Therapies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gene expression and cancer classification
- Health Systems, Economic Evaluations, Quality of Life
- Colorectal Cancer Screening and Detection
- Global Cancer Incidence and Screening
- Lung Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Cancer Treatment and Pharmacology
- Economic and Financial Impacts of Cancer
- RNA modifications and cancer
- Salivary Gland Tumors Diagnosis and Treatment
- Multiple and Secondary Primary Cancers
- Cardiac, Anesthesia and Surgical Outcomes
- Viral-associated cancers and disorders
- Brain Metastases and Treatment
Koo Foundation Sun Yat-Sen Cancer Center
2015-2024
Pingtung Christian Hospital
2020-2024
National Taiwan University Hospital
2024
Health Net
2021
National Cheng Kung University
2018
Sun Yat-sen University
2016
Sun Yat-sen University Cancer Center
2016
Duke Medical Center
2004-2012
University of California, Los Angeles
2009
VA Greater Los Angeles Healthcare System
2009
Global health systems are shifting toward value-based care in an effort to drive better outcomes the setting of rising costs. This shift requires a common definition value, starting with that matter most patients.The International Consortium for Health Outcomes Measurement (ICHOM), nonprofit initiative, was formed define standard sets by medical condition. In this article, we report efforts ICHOM's working group colorectal cancer.The composed multidisciplinary oncology specialists medicine,...
It is unclear whether germline breast cancer susceptibility gene mutations affect related outcomes. We wanted to evaluate mutation patterns in 20 genes and correlate the with clinical characteristics determine effects of these on prognosis. The study cohort included 480 ethnic Chinese individuals Taiwan at least one six risk factors for hereditary cancer: family history or ovarian cancer, young age onset bilateral triple negative both male cancer. PCR-enriched amplicon-sequencing a next...
This study aims to explore gene expression profiles that are associated with locoregional (LR) recurrence in breast cancer after mastectomy.A total of 94 patients who underwent mastectomy between 1990 and 2001 had DNA microarray on the primary tumor tissues were chosen for this study. Eligible patient should have no evidence LR without postmastectomy radiotherapy (PMRT) a minimum 3-year follow-up (n = 67) any 27). They randomly split into training validation sets. Statistical classification...
International initiatives increasingly advocate physician adherence to clinical protocols that have been shown improve outcomes, yet the process-outcome relationship for adhering breast cancer care protocol is unknown.This study explores whether 100% a set of quality indicators applied individuals with associated better survival.Ten (4 diagnosis-related and 6 treatment-related indicators) were used measure in 1378 patients treated from 1995 2001. Adherence each indicator was based on number...
Two Epstein-Barr virus (EBV)-based testing approaches have shown promise for early detection of nasopharyngeal carcinoma (NPC). Neither has been independently validated nor their performance compared. We compared diagnostic in an independent population.
We validated an 18-gene classifier (GC) initially developed to predict local/regional recurrence after mastectomy in estimating distant metastasis risk. The scoring algorithm defines scores as: <21, low risk; ≥21, high Six hundred eighty-three patients with primary operable breast cancer and fresh frozen tumor tissues available were included. outcome was the 5-year probability of freedom from (DMFP). Two external datasets used test predictive accuracy 18-GC. rates DMFP for classified as...
<h3>Importance</h3> Value-driven payment system reform is a potential tool for aligning economic incentives with the improvement of quality and efficiency health care containment cost. Such has not been researched satisfactorily in full-cycle cancer care. <h3>Objective</h3> To examine association outcomes medical expenditures bundled-payment pay-for-performance program breast Taiwan compared fee-for-service (FFS) program. <h3>Design, Setting, Participants</h3> Data were obtained from Cancer...
This study aimed to develop a prognostic model predict the breast cancer-specific survival and overall for cancer patients in Asia demonstrate significant difference clinical outcomes between Asian non-Asian patients.
Salmonella mycotic thoracic aortic aneurysm is a rare but life-threatening condition. We report 59-year-old man with two aneurysms, presented fever and chills associated hoarseness due to left vocal cord palsy (Cardiovocal syndrome). Successful endovascular repair was performed using Talent stent-graft devices deployed separately cover the aneurysms. Subsequent computed tomography at 12 months after operation confirmed exclusion of pseudoaneurysms no endoleak. With potent antibiotics careful...
Although performance measurement for assessing care quality is an emerging area, a system measuring the of cancer at hospital level has not been well developed. The purpose this study was to develop organization-based core measures colorectal patient and apply these compare performance. development undergone three stages including modified Delphi method. sample originated from 2004 data in Taiwan Cancer Database, national registry. Eighteen hospitals 5585 newly diagnosed patients were...
This study is to evaluate the associations between long-term survival and stage I breast cancer by examining hormonal receptor (HR) human epidermal growth factor receptor-2 (HER2) status. A total of 1595 patients who were seen from 1990 2008 with surgery as first treatment pathology (T1N0) included in this study. HR HER2 status used approximate subtypes. Additionally, ten-year relapse-free (RFS) rate failure patterns each subtype evaluated. Multivariate analyses performed identify risk...
Background: This study examined the current American Joint Committee on Cancer (AJCC) 8th edition staging system and proposes a new classification for nasopharyngeal carcinoma (NPC). Methods: One thousand four hundred eighteen newly diagnosed patients with NPC without distant metastasis from 1995 through 2010 were identified. Patients treated three-dimensional conformal radiotherapy (3D-CRT) used as training cohort. Based T N categories of AJCC 7th system, recursive partitioning analysis...
Abstract Purpose This study aims to raise awareness of the disparities in survival predictions among races head and neck cancer (HNC) patients by developing validating population-based prognostic models specifically tailored for Taiwanese Asian populations. Methods A total 49,137 diagnosed with HNCs were included from Taiwan Cancer Registry (TCR). Six models, divided into three categories based on surgical status, developed predict both overall (OS) cancer-specific using registered...
Department of Anesthesiology, National Taiwan University Hospital, Taipei, Taiwan, [email protected]
The COVID-19 pandemic has profoundly affected cancer care worldwide, including radiation therapy (RT) for breast (BC), because of risk-based resource allocation. We report the evolution international RT practices during beginning pandemic, focusing on differences in treatment recommendations between countries.Between July and November 2020, a 58-question survey was distributed to oncologists (ROs) through professional societies. Changes decision making first surge were evaluated across six...