A5076088266- Palliative Care and End-of-Life Issues
- Childhood Cancer Survivors' Quality of Life
- Patient Dignity and Privacy
- Cancer survivorship and care
- Ovarian cancer diagnosis and treatment
- Ethics in medical practice
- Patient-Provider Communication in Healthcare
- Economic and Financial Impacts of Cancer
- PARP inhibition in cancer therapy
- Family and Patient Care in Intensive Care Units
- Cannabis and Cannabinoid Research
- Health Systems, Economic Evaluations, Quality of Life
- Genetic factors in colorectal cancer
- Cancer Immunotherapy and Biomarkers
- BRCA gene mutations in cancer
- Pain Management and Opioid Use
- Advances in Oncology and Radiotherapy
- Opioid Use Disorder Treatment
- Cardiac Arrest and Resuscitation
- Healthcare Decision-Making and Restraints
- Innovations in Medical Education
- Healthcare professionals’ stress and burnout
- Ethics in Clinical Research
- Cancer Genomics and Diagnostics
- Frailty in Older Adults
Tufts Medical Center
2022-2025
Tufts University
2022-2024
UConn Health
2024
Hadassah Medical Center
2013-2024
Beth Israel Deaconess Medical Center
2013-2022
Harvard University
2011-2022
University Health Network
2022
Princess Margaret Cancer Centre
2022
University of Toronto
2022
General Department of Preventive Medicine
2011-2021
Despite the tissue-agnostic approval of pembrolizumab in mismatch repair deficient (MMRD) solid tumors, important unanswered questions remain about role immune checkpoint blockade repair-proficient (MMRP) and -deficient endometrial cancer (EC).This phase II study evaluated PD-L1 inhibitor avelumab two cohorts patients with EC: (1) MMRD/POLE (polymerase ε) cohort, as defined by immunohistochemical (IHC) loss expression one or more (MMR) proteins and/or documented mutation exonuclease domain...
BackgroundOlaparib is a poly(ADP-ribose) polymerase inhibitor and cediranib an oral anti-angiogenic. In the primary analysis of this phase II study, combination cediranib/olaparib improved progression-free survival (PFS) compared with olaparib alone in relapsed platinum-sensitive ovarian cancer. This updated was conducted to characterize overall (OS) update PFS outcomes.Patients methodsNinety patients were enrolled randomized, open-label, study between October 2011 June 2013 across nine...
Informal caregivers (family and friends) of people with cancer are often unprepared for their caregiving role, leading to increased burden or distress. Comprehensive Health Enhancement Support System (CHESS) is a Web-based lung information, communication, coaching system caregivers. This randomized trial reports the impact on caregiver burden, disruptiveness, mood providing access CHESS versus Internet list recommended websites.A total 285 informal patients advanced nonsmall cell were...
Abstract BACKGROUND: Palliative care is recognized as integral to the practice of oncology, yet many oncologists report inadequate training in critical palliative domains, such symptom management, psychosocial care, and communication skills. The authors this sought assess quantity quality education within oncology fellowships. METHODS: Second‐year fellows completed a 104‐item survey that was modified adapted from national medical students residents. Items allowed comparison between...
Recent publications have promoted physician-patient communication on cost as a means of decreasing overall spending and minimizing patients' financial burden in oncology. No study has assessed perspectives We sought to describe oncology attitudes toward communication, explore potential predictors for preferences, assess how patients with cancer consider when making management decisions.A 31-item questionnaire was developed measure preferences regarding the care, focusing out-of-pocket costs....
Purpose: Integrated into routine oncology care, palliative care can improve symptom burden, quality of life, and patient caregiver satisfaction. However, not all practices have access to specialist medicine. This project endeavored define what constitutes high-quality primary as delivered by medical practices. Methods: An expert steering committee outlined 966 service items, in nine domains, each describing a candidate element delivery for patients with advanced cancer or high burden. Using...
Global health systems are shifting toward value-based care in an effort to drive better outcomes the setting of rising costs. This shift requires a common definition value, starting with that matter most patients.The International Consortium for Health Outcomes Measurement (ICHOM), nonprofit initiative, was formed define standard sets by medical condition. In this article, we report efforts ICHOM's working group colorectal cancer.The composed multidisciplinary oncology specialists medicine,...
To assess the feasibility of early palliative care in ambulatory setting patients with newly diagnosed advanced non-small-cell lung cancer (NSCLC).Patients were eligible if they had a performance status 0 to 1 and within 8 weeks diagnosis NSCLC. Participants received integrated from oncology throughout course their disease. scheduled meet team (PCT) complete quality-of-life (QOL) mood questionnaires monthly for 6 months. The study was deemed feasible 64% completed at least 50% visits QOL...
Abstract BACKGROUND: In this study, the authors examined effectiveness of an online support system (Comprehensive Health Enhancement Support System [CHESS]) versus Internet in relieving physical symptom distress patients with non–small cell lung cancer (NSCLC). METHODS: total, 285 informal caregiver‐patient dyads were assigned randomly to receive, for up 25 months, standard care plus training on and access either use a list sites about (the arm) or CHESS arm). Caregivers agreed complete...
PURPOSE: To explore how well medical schools prepare students to address end-of-life issues with their patients. METHOD: In 1997, the authors surveyed 226 fourth-year at Georgetown University School of Medicine and Mayo Medical School, assessing relevant knowledge, experiences, attitudes, students' sense preparedness issues. RESULTS: Seventy-two percent (162) eligible responded. Almost all (99%) recognized importance advance directives anticipated discussing patients in practices (84%)....
Background: Delirium, a common complication of advanced cancer, may put caregivers at risk for poor mental health outcomes. We looked relationship between caregiver-perceived delirium in patient with cancer and rates caregiver psychiatric disorders. Methods: Using cross-sectional data from 200 patients life expectancy less than 6 months, we determined the frequency delirium, which was defined as who reported witnessing "confused, delirious" on Stressful Caregiving Response to Experiences...
Background: Oncology providers often lack the confidence to make clinical recommendations about medical cannabis (MC). This study aimed develop and evaluate feasibility of implementing an educational curriculum on use MC in patient care for oncology trainees. Methods: A multidisciplinary team designed oncology. The was piloted as a 1-hour interactive webinar across 8 United States–based hematology/oncology fellowship programs between 2022 2023. Incentivized surveys measuring outcomes,...
Background: Residents are often responsible for eliciting patients' treatment preferences at the end of life (EOL), yet we have a limited understanding their competence in this task. Objective: To assess medical residents to discuss advance directives (AD) with patients using two measures: self-assessment (perceived competence) and self-reported behaviors (behavioral competence). examine relationship between educational experiences these measures competence. Design: Cross-sectional...
DOI: 10.1200/JCO.2014.60.3274 Case Vignette “We’ve been waiting for you to come on the oncology service,” fellow said, as resident and nurse practitioner service looked on. “We have a really challenging case.” Our patient was frail 77-year-old woman with unresectable pancreatic adenocarcinoma, saddle pulmonary embolus, protein calorie malnutrition, hepatitis C, recurrent infections, all of which had resulted in lengthy hospital stay. Her cancer progressed despite two lines chemotherapy. She...
Older adults compose the majority of patients with cancer in United States; however, it is unclear how well geriatrics or geriatric oncology training being incorporated into hematology-oncology (hem-onc) fellowships.A convenience sample hem-onc fellows completed a (written electronic) survey assessing their education, clinical experiences, and perceived proficiency during training; knowledge base oncology; confidence managing older cancer; general attitudes toward principles.Forty-five...