Shyuang‐Der Terng
A5045012438- Head and Neck Cancer Studies
- Head and Neck Surgical Oncology
- Salivary Gland Tumors Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Oral Health Pathology and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Viral-associated cancers and disorders
- Lung Cancer Treatments and Mutations
- Tracheal and airway disorders
- Lung Cancer Research Studies
- Polyomavirus and related diseases
- Parvovirus B19 Infection Studies
- Brain Metastases and Treatment
- Fibroblast Growth Factor Research
- Oral and Maxillofacial Pathology
- Management of metastatic bone disease
- Reconstructive Facial Surgery Techniques
- Cleft Lip and Palate Research
- Ear and Head Tumors
- Pancreatic and Hepatic Oncology Research
- Lung Cancer Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Reconstructive Surgery and Microvascular Techniques
Koo Foundation Sun Yat-Sen Cancer Center
2011-2025
Two Epstein-Barr virus (EBV)-based testing approaches have shown promise for early detection of nasopharyngeal carcinoma (NPC). Neither has been independently validated nor their performance compared. We compared diagnostic in an independent population.
The question as to whether prolonged diagnosis-to-surgery intervals (DSIs) may compromise survival outcomes in patients with oral cavity squamous cell carcinoma (OCSCC) remains unanswered. This nationwide study was designed address this issue. We analyzed data from 26,214 first primary OCSCC identified the Taiwanese Cancer Registry Database between 2011 and 2021. optimal DSI cutoff determined based on 5-year disease-specific (DSS) overall (OS) rates using Cox regression analysis. Patients...
The current NCCN guidelines advocate for the use of adjuvant radiotherapy (RT) or chemoradiotherapy (CRT) in pT3N0 oral cavity squamous cell carcinoma (OCSCC). Here, we sought to evaluate whether postoperative RT/CRT may confer a survival advantage patients who lack adverse pathological features. A dataset 852 OCSCC treated between 2018 and 2021 was analyzed. Patients with features (i.e., positive margins, margins <5 mm, lymphovascular invasion, perineural invasion) were excluded, leaving...
Conduct an accurate risk assessment of resected oral cavity squamous cell carcinoma (OSCC) patients by accessing a nationwide systemic investigation is pivotal to improve treatment outcomes. In this article, we tried determine the impact different prognostic factors for OSCC who received adjuvant radiotherapy (RT) after curative surgery, using Taiwan's national cancer registry database (TCR). A nationwide, large population-based study was conducted TCR with identified from 2007 2015. The...
Abstract Background The study aims are to evaluate the associations between nasopharyngeal carcinoma (NPC) risk and cigarette smoking explore effects of on Epstein‐Barr virus (EBV) infection for NPC risk. Methods 1235 male cases 1262 hospital‐based controls matched were recruited across six collaborative hospitals 2010 2014. Using a standardized questionnaire, information other potential factors was obtained. Blood collected used anti‐EBV VCA IgA EA‐EBNA1 testing using standard methods....
Abstract Background The current NCCN guidelines recommend considering elective neck dissection (END) for early‐stage oral cavity squamous cell carcinoma (OCSCC) with a depth of invasion (DOI) exceeding 3 mm. However, this DOI threshold, determined by evaluating the occult lymph node metastatic rate, lacks robust supporting evidence regarding its impact on patient outcomes. In nationwide study, we sought to explore specific indications END in patients diagnosed OCSCC at stage cT2N0M0, as...
Abstract Background and Objectives The treatment paradigm for advanced hypopharyngeal cancer has shifted from surgical approaches to organ preservation. However, recent studies indicated that may be associated with better survival rates. This study aimed conduct a head‐to‐head comparison of outcomes complications versus nonsurgical using nationwide database. Methods Using data set, we gathered 2196 propensity score‐matched patients stage III/IVa cancer. We compared rates among treatment....
To compare the clinical outcomes of two treatment modalities, initial surgery and primary definitive radiotherapy (RT), in Taiwanese patients diagnosed with cT1-2N0M0 oral cavity squamous cell carcinoma (OCSCC).
Abstract Background Elective tracheotomy is commonly performed in resected oral squamous cell carcinoma (OCSCC) to maintain airway patency. However, the indications for this procedure vary among surgeons. This nationwide study evaluated impact of on both duration in‐hospital stay and long‐term survival outcomes patients with OCSCC. Methods A total 18,416 OCSCC were included analysis, comprising 7981 who underwent elective 10,435 did not. The primary assessed 5‐year disease‐specific (DSS)...
Background Head and neck cancer is increasingly being managed through nonsurgical approaches. Evidence comes from studies that have mainly examined patients with laryngeal cancer. Few studies, limited sample size, focused on the comparative outcomes of surgical approaches in advanced oropharyngeal or hypopharyngeal Methods Using a national database, we identified 1603 1512 clinical stage III/IVA cancer, respectively, treated between 2004 2009. The study cohort was followed until 2012,...
Patients with nasopharyngeal carcinoma (NPC) are common in Taiwan. To provide efficient management to patients, the surgeons often perform cytological imprints immediately after biopsies of lesions suspicious for NPC. The results assessment usually reported within 30 min biopsies. patients positive can then be arranged further examinations during same visit. We reviewed 191 and corresponding from 187 1997-2004 at Koo Foundation Sun Yat-Sen Cancer Center, Taipei. diagnoses were categorized...
Abstract Background While surgery remains the primary treatment for oral squamous cell carcinoma (OCSCC), induction chemotherapy (IC) can be used as a bridging or neoadjuvant therapy. This nationwide study in Taiwan examines survival outcomes of OCSCC patients who received IC before surgery. Methods We analyzed data from 29,891 with OCSCC. Of these, 29,058 initially underwent (OP group), whereas 833 (IC + OP group). A propensity score (PS)‐matched analysis (4, 1 ratio, 3260 vs. 815 patients)...
The evidence for adjuvant chemoradiotherapy (CRT) of oral cavity squamous cell carcinoma (OCSCC) with extra-nodal extension (ENE) in National Comprehensive Cancer Network (NCCN) guidelines is derived from patients head and neck cancer. further suggest a radiation dose ranging 6000 to 6600 cGy. In this nationwide study, we sought evaluate the prognostic significance therapy specific dosage Taiwanese pure OCSCC ENE. A retrospective analysis 1577 ENE who underwent resection received CRT or...
In the treatment of oral cavity squamous cell carcinoma (OCSCC), surgical quality measures which are expected to affect outcomes, including achievement a clear margin, surgeon-dependent but might not be invariably associated with hospital volume. Our objective was explore margin variations and survival differences OCSCC between two highest-volume hospitals in Taiwan. A total 2009 1019 patients who were treated at Taiwanese (termed Hospital 1 2, respectively) included. We examined how...