A5005592075- Head and Neck Cancer Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Esophageal Cancer Research and Treatment
- Ear and Head Tumors
- Otolaryngology and Infectious Diseases
- Cancer-related gene regulation
- Head and Neck Anomalies
- Trigeminal Neuralgia and Treatments
- Oral health in cancer treatment
- Tracheal and airway disorders
- Lung Cancer Treatments and Mutations
- Cerebral Venous Sinus Thrombosis
- Cancer Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Cervical Cancer and HPV Research
- Inflammatory Biomarkers in Disease Prognosis
- Protease and Inhibitor Mechanisms
- NF-κB Signaling Pathways
- Thyroid Cancer Diagnosis and Treatment
- Effects of Environmental Stressors on Livestock
- Pancreatic and Hepatic Oncology Research
- Economic and Financial Impacts of Cancer
Linkou Chang Gung Memorial Hospital
2021-2025
Chang Gung University
2021-2025
Chang Gung Memorial Hospital
2018-2025
Taoyuan Chang Gung Memorial Hospital
2021-2024
Memorial Hospital of South Bend
2024
Ludwig-Maximilians-Universität München
2020
German Center for Lung Research
2020
United States Department of Agriculture
2017
National Defense Medical Center
1996-2003
A newly introduced pan-immune-inflammation value (PIV) was not evaluated for its role in oral cavity squamous cell carcinoma (OSCC). In this study, the PIV calculated with following equation (neutrophil count × platelet monocyte count)/lymphocyte from results of automated hematology analyzers 853 OSCC patients 2005 to 2017. The optimal cutoff preoperative 268, as determined by a receiver operating characteristic curve. Significant differences were observed alcohol consumption, smoking, pT...
Abstract Oral cavity squamous cell carcinoma (OSCC) represents the most prevalent malignancy among head and neck carcinomas (HNSCCs). Standard treatment modalities include surgical resection combined with radiation chemotherapy. However, locoregional failure remains a critical issue affecting prognosis of OSCC patients, largely due to tumor resistance against or In this study, we established gene database related recurrence identified PSMA2 as novel molecule influencing in patients. An...
Objective There is no useful tool to clinically predict the occurrence of osteoradionecrosis (ORN) mandible quantitatively. The aim was investigate risk factors, including different modalities radiotherapy, for developing mandibular ORN in patients undergoing marginal mandibulectomy and postoperative radiotherapy. Methods Between January 2006 December 2012, 167 subjects who underwent radiotherapy with were enrolled. association bone measurements patient variables analyzed, a nomogram...
Deep neck infection (DNI) is a serious disease that can lead to airway obstruction, and some patients require tracheostomy protect the instead of intubation. However, no previous study has explored risk factors associated with need for in DNI. This article investigates Between September 2016 February 2020, 403 subjects DNI were enrolled. Clinical findings critical deep spaces assessed. In univariate multivariate analysis, older age (≥65 years old) (OR = 2.450, 95% CI: 1.163–5.161, p 0.018),...
Esophageal cancer is a deadly disease, and neoadjuvant chemoradiotherapy can improve patient survival, particularly for patients achieving pathological complete response (ypCR). However, existing imaging methods struggle to accurately predict ypCR. This study explores computer-aided detection methods, considering both data radiotherapy dose variations enhance prediction accuracy. It involved with node-positive esophageal squamous cell carcinoma undergoing surgery, collected from 2014 2017,...
(1) Background: The optimal cutoff value that maximizes the prognostic of surgical margins in patients with resected oral cavity squamous cell carcinoma has not yet been identified. (2) Methods: Data for this study were retrieved from Taiwan Cancer Registry Database. A total 13,768 Taiwanese identified and stratified according to different margin statuses (0, 0.1–4 > 4 mm). five-year local control, disease-specific survival overall rates main outcome measures. (3) Results: 5-year close (0...
Abstract Objectives The aim of this meta‐analysis is to evaluate the potential benefits postoperative radiotherapy (PORT) in patients with pN1 oral cavity squamous cell carcinoma. Methods A literature search through major databases was conducted until January 2023. adjusted hazard ratio (aHR) or risk (RR) 95% confidence intervals (CIs) different survival outcomes were extracted and pooled. Results Ten studies published between 2005 2022, a pooled patient population 2888, included...
Deep neck infections (DNIs) such as parotid abscesses are medical emergencies with a seemingly different etiology and treatment course from other DNIs. We sought to confirm this in the present retrospective population-based cohort study. Between August 2016 January 2020, 412 patients DNIs seen at tertiary center were enrolled Infections of space compared those deep spaces, according patient characteristics. All divided into (PS; n = 91, 22.08%) non-parotid (NPS; 321, 77.92%) subgroups....
Abstract Background The administration of postoperative radiotherapy remains controversial in pN1 oral cavity cancer patients without extranodal extension. aim is to determine whether reduces the neck recurrence rate and improves survival outcomes patients. Methods This study consecutively enrolled 1056 with newly diagnosed squamous cell carcinoma who underwent tumor wide excision dissection from September 2002 November 2019. One hundred two extension were eligible for analysis. Then, a...
Carcinoma showing thymus-like differentiation (CASTLE) is a rare malignant tumor that accounts for 0.1%-0.15% of all thyroid cancers. More than half the patients have extension to adjacent organs, including recurrent laryngeal nerve, trachea, and esophagus. The diagnosis CASTLE based on histology immunohistochemistry. A 58-year-old female patient complained hoarseness one years. Right side vocal cord palsy was diagnosed by fiberscopy. Thyroid sonography revealed right tumors, which were...
Background: The prognosis of patients with resected esophageal squamous cell carcinoma after neoadjuvant chemoradiotherapy is particularly poor in those who were staged as ypT3/T4 and/or ypN+. This study investigated whether adjuvant was associated improved clinical outcomes these patients. Methods: we identified ypN+ being treated followed by esophagectomy between the years 2013 and 2019. Patients divided into two groups based on they received chemoradiotherapy. Kaplan-Meier method Cox...
<title>Abstract</title> <bold>Objective: </bold>The lymph node to primary tumor standardized uptake value ratio (NTR) is an innovative parameter derived from positron emission tomography (PET) scans that captures the intricate relationship between tumors and associated nodes. This meta-analysis aimed investigate prognostic of NTR in cancer patients. <bold>Methods:</bold> A systematic search PubMed, Cochrane, Embase databases was conducted identify studies investigating association survival...
Purpose The aim of this was to evaluate the prognostic significance nodal-to-primary tumor SUV max ratio (NTR) in patients with node-positive hypopharyngeal squamous cell carcinoma (HPSCC) treated radiotherapy or without concurrent chemotherapy. study aims enhance accuracy by incorporating NTR into American Joint Committee on Cancer (AJCC) staging system. Patients and Methods This retrospective included 191 biopsy-proven HPSCC from 2005 2013. calculated as metastatic lymph nodes primary...
Purpose This multicenter study investigates the efficacy of 18 F-FDG PET/CT in postradiotherapy (post-RT) response evaluation salivary gland carcinoma (SGC). Methods We retrospectively reviewed 115 SGC patients who underwent definitive or adjuvant RT followed by between 2004 and 2021. Most tumors were parotid malignancies (50%). The most common histological subtypes adenoid cystic (29%) mucoepidermoid carcinomas (18%). Results median follow-up was 65 months. Post-RT anatomic images (CT/MRI)...
Abstract Objectives We investigate if sublingual space invasion (SLI) determined on magnetic resonance imaging confers differences in clinicopathological manifestations and treatment outcomes of oral tongue squamous cell carcinoma (OTSCC). Study Design Retrospective cohort study. Setting Tertiary Academic Medical Center. Methods 221 OTSCC patients were included. Cox regression models Kaplan‐Meier methods used, nomogram construction was performed, incorporating SLI with other adverse factors,...
Abstract Background: For endoscopic endonasal reconstruction of skull base defects, minimizing the sequelae Cerebrospinal Fluid (CSF) leakage, graft migration, and infection is challenging. This study aims to evaluate outcomes multilayer autologous rigid buttress in patients with olfactory neuroblastoma. Methods: retrospectively reviews records neuroblastoma who underwent surgery a at one institution between May 2015 December 2021. After tumor resection, was performed using multilayered...