A5083120643- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Lymphoma Diagnosis and Treatment
- CNS Lymphoma Diagnosis and Treatment
- Head and Neck Cancer Studies
- Moyamoya disease diagnosis and treatment
- Inflammatory Biomarkers in Disease Prognosis
- Liver Disease and Transplantation
- Acute Lymphoblastic Leukemia research
- Venous Thromboembolism Diagnosis and Management
- Bone and Joint Diseases
- Lung Cancer Research Studies
- Lung Cancer Treatments and Mutations
Linkou Chang Gung Memorial Hospital
2019-2024
Chang Gung University
2020-2024
China Medical University
2017-2020
China Medical University Hospital
2017-2020
Taipei Veterans General Hospital
2020
National Yang Ming Chiao Tung University
2019-2020
National Yang Ming University Hospital
2019
Patients on oral antiviral (OAV) therapy remain at hepatocellular carcinoma (HCC) risk. Risk prediction tools distinguishing treated patients with residual HCC risk are limited. The aim of this study was to develop an accurate, precise, simple-to-use score using routine clinical variables among a Asian cohort.Adult chronic hepatitis B (CHB) OAV were recruited from 25 centers in the United States and Asia-Pacific region. Excluded persons coinfected C, D, or human immunodeficiency virus, had...
// Chien-Hung Chen 1 , Chuan-Mo Lee Hsueh-Chou Lai 2 Tsung-Hui Hu Wen-Pang Su Sheng-Nan Lu Chia-Hsin Lin Chao-Hung Hung Jing-Houng Wang Mei-Hsuan 3 and Cheng-Yuan Peng 2, 4 Division of Hepatogastroenterology, Department Internal Medicine, Kaohsiung Chang Gung Memorial Hospital University College Kaohsiung, Taiwan China Medical Hospital, Taichung, Institute Clinical National Yang-Ming University, Taipei, School Correspondence to: Peng, email: cypeng@mail.cmuh.org.tw Keywords: nucleos(t)ide...
Abstract Background Although various prognostic models for primary central nervous system lymphoma (PCNSL) have been developed, there is no consensus regarding the optimal index. We aimed to evaluate potential factors and construct a novel predictive model PCNSL patients. Methods enrolled newly diagnosed patients between 2003 2015. The endpoint was progression‐free survival (PFS), secondary overall (OS). identified using multivariate Cox proportional hazards were used develop model....
Abstract We developed an optimal noninvasive index comprising routine laboratory parameters for predicting cirrhosis in chronic hepatitis B (CHB) and C (CHC) patients. This study included 992 CHB patients 1,284 CHC who received liver biopsy. the new index, named modified Fibrosis-4 (mFIB-4) according to four independent variables of model: age, aspartate aminotransferase (AST), alanine (ALT), platelet count. The formula mFIB-4 is 10 × Age(years) AST(U/L)/Platelet count(10 9 /L) ALT(U/L). For...
Abstract Early declines in serum hepatitis B surface (HBsAg) levels, their optimal cutoffs, and association with therapeutic endpoints chronic (CHB) patients receiving entecavir treatment remain unclear. We prospectively enrolled 529 (195 e antigen [HBeAg]-positive 334 HBeAg-negative) a median duration of 49.2 months. Median HBsAg levels declined significantly both groups at Month 3, but only Months 6–12 the HBeAg-negative group. Both exhibited significant decline each successive year...
Abstract Objectives To investigate the prognostic value of preoperative systemic immune‐inflammation index (SII) in patients with oral cavity squamous cell carcinoma (OC‐SCC) treated curative surgery followed by adjuvant radiotherapy (RT) or chemoradiotherapy (CCRT). Materials and Methods We retrospectively reviewed clinical records OC‐SCC who received postoperative RT/CCRT between January 2005 December 2012. Blood samples were drawn 2 weeks preceding surgery. SII was calculated multiplying...
Noninvasive fibrosis indices can help stratify the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B (CHB) receiving nucleos(t)ide analogue (NA) therapy. We investigated predictive performance on-treatment changes FIB-4 (△FIB-4) and 1-year values (FIB-4 12M) for HCC CHB entecavir included 1325 NA-naïve treated entecavir, retrospectively, from January 2007 to August 2012. A combination △FIB-4 12M was used cumulative into three subgroups each noncirrhotic cirrhotic p...
Background: Overall survival of patients with primary CNS lymphoma (PCNSL) has improved since the introduction immunochemotherapy. However, up to 10-15% PCNSL still die shortly after diagnosis. In present study, we aimed investigate risk factors early mortality (death within 60 days diagnosis) in PCNSL. Methods: We included newly diagnosed a tertiary medical center Taiwan between January 1, 2002 and May 31, 2018. Clinical were collected compared who had did not have mortality. Results: A...
Frontline intensification (including consolidative whole-brain radiotherapy or high-dose chemotherapy with autologous stem-cell transplantation after induction therapy) has been proposed to treat primary central nervous system lymphoma (PCNSL). However, no prospective randomized trials have answered whether frontline can offer a survival benefit PCNSL patients. We aim clarify the outcomes and influence of on real-world patients different risk-stratified PCNSLs.Between January 2003 December...
Purpose The aim of this was to evaluate the prognostic significance nodal-to-primary tumor SUV max ratio (NTR) in patients with node-positive hypopharyngeal squamous cell carcinoma (HPSCC) treated radiotherapy or without concurrent chemotherapy. study aims enhance accuracy by incorporating NTR into American Joint Committee on Cancer (AJCC) staging system. Patients and Methods This retrospective included 191 biopsy-proven HPSCC from 2005 2013. calculated as metastatic lymph nodes primary...