- Cardiac Arrhythmias and Treatments
- Endometrial and Cervical Cancer Treatments
- Meningioma and schwannoma management
- Cancer, Hypoxia, and Metabolism
- Cardiac pacing and defibrillation studies
- Cervical Cancer and HPV Research
- Atrial Fibrillation Management and Outcomes
- Angiogenesis and VEGF in Cancer
- Cardiac electrophysiology and arrhythmias
- Neurofibromatosis and Schwannoma Cases
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Immune cells in cancer
- Head and Neck Surgical Oncology
- Prostate Cancer Treatment and Research
- Inflammatory Biomarkers in Disease Prognosis
- Glioma Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Colorectal and Anal Carcinomas
- Pituitary Gland Disorders and Treatments
- Immune Cell Function and Interaction
- Uterine Myomas and Treatments
- Radiation Therapy and Dosimetry
- Advanced Radiotherapy Techniques
- Dysphagia Assessment and Management
Chang Gung Memorial Hospital
2006-2025
Chang Gung University
2016-2025
ITRI International
2025
Linkou Chang Gung Memorial Hospital
2014-2024
Taichung Veterans General Hospital
2019-2022
Central Taiwan University of Science and Technology
2020-2022
Taoyuan Chang Gung Memorial Hospital
2021-2022
National Taiwan University Hospital
2020
National Defense Medical Center
2019
Tri-Service General Hospital
2019
To investigate how single or fractionated doses of radiation change the microenvironment in transgenic adenocarcinoma mouse prostate (TRAMP)-C1 tumors with respect to vascularity, hypoxia, and macrophage infiltrates.Murine TRAMP-C1 were grown C57BL/6J mice 4 mm tumor diameter irradiated either 25 Gy a dose 60 15 fractions. Changes infiltrates assessed by immunohistochemistry molecular assays.Tumor growth was delayed for 1 week after both schedules. Tumor microvascular density (MVD)...
Atrial fibrillation (AF)-associated embolic stroke is preventable, and AF detection may help to prevent in subjects with paroxysmal AF. We aimed evaluate the performance of smartwatch photoplethysmography (PPG) feasibility ambulatory monitoring for daily life.Consecutive who underwent Holter electrocardiogram (ECG) or burden evaluation were enrolled. The participants 24 hours simultaneous ECG continuous PPG recording using a Garmin smartwatch. signals processed noise rejection, beat...
Atypical and malignant meningiomas are rare. Our aim was to examine the treatment outcomes following surgical resection, analyze associations between clinical characteristics overall survival (OS) or relapse free (RFS). 102 patients with atypical underwent microsurgical resection June 2001 November 2009 were analyzed retrospectively. We compared demographics, characteristics, treatment, complications. The five-year ten-year rates 93.5% 83.4%, respectively. Three factors significantly reduced...
Background: Brain metastases are observable in 20–40% of non-small cell lung cancer patients, but standard treatments for such may be intolerable to some. Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) were found effective against mutant-EGFR adenocarcinomas, data regarding their effectiveness, especially the second-generation EGFR-TKI afatinib, is limited. This study compared key outcomes afatanib monotherapy versus afatinib combined with whole-brain radiotherapy...
ABSTRACT Background Randomized clinical trials demonstrated similar efficacy and improved safety of direct oral anticoagulants versus warfarin in patients with atrial fibrillation (AF). Long‐term data routine practice are needed. Hypothesis Patients AF receiving edoxaban at baseline continue to have low annualized effectiveness event rates the second year follow‐up, regional variations observed. Methods The Global ETNA‐AF program is a prospective, noninterventional study edoxaban. Patient...
This study develops an eco-friendly non-destructive testing method for powder metallurgy, aiming to improve inspection techniques like magnetic particle inspection, given environmental impacts. The primary goal is establish intelligent manufacturing-based AI system detecting internal cracks in metallurgy components after sintering. Acoustic data collected using electric hammer and microphone sintering processed create spectrograms. An autoencoder extracts features, followed by cluster...
Results of this study indicate a radioprotective effect peroxiredoxin-I. Peroxiredoxin-I is an antioxidant that scavenges hydroperoxides, whereas reactive oxygen species are the main mediators ionizing radiation toxicity. We hypothesized peroxiredoxin-I might be induced by cellular exposure to and act protect them against its cytotoxic effects. Western blot Northern analyses were used assess protein mRNA expression. Rat C6 glioma cells engineered overexpress sense or antisense human using...
Abstract Objectives To investigate the prognostic value of preoperative systemic immune‐inflammation index (SII) in patients with oral cavity squamous cell carcinoma (OC‐SCC) treated curative surgery followed by adjuvant radiotherapy (RT) or chemoradiotherapy (CCRT). Materials and Methods We retrospectively reviewed clinical records OC‐SCC who received postoperative RT/CCRT between January 2005 December 2012. Blood samples were drawn 2 weeks preceding surgery. SII was calculated multiplying...