A5006765593- Esophageal Cancer Research and Treatment
- Head and Neck Cancer Studies
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Lung Cancer Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Oral Health Pathology and Treatment
- Head and Neck Surgical Oncology
- Cancer Diagnosis and Treatment
- Pleural and Pulmonary Diseases
- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical Practices and Patient Outcomes
- Pancreatic and Hepatic Oncology Research
- Pneumonia and Respiratory Infections
- Reconstructive Surgery and Microvascular Techniques
- Smoking Behavior and Cessation
- Radiomics and Machine Learning in Medical Imaging
- Ear and Head Tumors
- Diabetes Treatment and Management
- Gallbladder and Bile Duct Disorders
- Tracheal and airway disorders
- Dysphagia Assessment and Management
- Hospital Admissions and Outcomes
- Liver Disease and Transplantation
Chang Gung Memorial Hospital
2013-2025
Chang Gung University
2016-2025
Chiayi Chang Gung Memorial Hospital
2024
Linkou Chang Gung Memorial Hospital
2017-2024
Tokai University Hospital
2022
National Taiwan University
2006-2015
Maine Farmland Trust
2015
National Taiwan University Hospital
2015
National Yang Ming Chiao Tung University
2015
Chinese Culture University
2006
Integrating primary prevention into care pathways for older adults is a core strategy of healthy ageing, but evidence remains limited. We aimed to determine whether incorporating multidomain intervention health could improve standard value-based outcomes and quality life.For this Taiwan Integrated Geriatric Care (TIGER) study, pragmatic randomised controlled trial, we recruited community-dwelling outpatients aged 65 years or with at least three chronic medical conditions. excluded people...
Surgery for oesophageal squamous cell carcinoma involves dissecting lymph nodes along the recurrent laryngeal nerve. This is technically challenging and injury to nerve may lead vocal cord palsy, which increases risk of pulmonary complications. The aim this study was compare efficacy safety robot-assisted oesophagectomy (RAO) versus video-assisted thoracoscopic (VAO) dissection left RLN.
Radical lymph node dissection (LND) along the left recurrent laryngeal nerve (RLN) is surgically demanding and can be associated with substantial postoperative morbidity. The question of whether robot-assisted esophagectomy (RE) might superior to video-assisted thoracoscopic (VATE) for performing LND RLN in patients esophageal squamous cell carcinoma (ESCC) remains open.We will conduct a multicenter, open-label, randomized controlled trial (Robotic-assisted Esophagectomy vs Video-Assisted...
Care retention and medication adherence are crucial for individuals living with human immunodeficiency virus (HIV). Discrepancies exist between real-world evidence randomized trials regarding early antiretroviral therapy (ART) initiation care retention. We investigated the effects of same-day ART on discontinuation in new patients acquired syndrome (AIDS) those newly infected HIV. The two groups commenced from January 2017 to December 2021 Taiwan. Data were collected National Health...
The question as to whether prolonged diagnosis-to-surgery intervals (DSIs) may compromise survival outcomes in patients with oral cavity squamous cell carcinoma (OCSCC) remains unanswered. This nationwide study was designed address this issue. We analyzed data from 26,214 first primary OCSCC identified the Taiwanese Cancer Registry Database between 2011 and 2021. optimal DSI cutoff determined based on 5-year disease-specific (DSS) overall (OS) rates using Cox regression analysis. Patients...
In this study, we evaluated the factors associated with a pathologic complete response (pCR) after neoadjuvant chemoradiotherapy (nCRT) for esophageal squamous cell carcinoma (ESCC). Pre-nCRT parameters in ESCC patients treated between 1999 and 2006 were analyzed to identify predictors of pCR. All received 5-fluorouracil/cisplatin-based chemotherapy external beam radiation followed by scheduled esophagectomy. Variables using univariate multivariate analyses pCR as dependent variable....
Objectives To assess the costs of health effects cigarette smoking and secondhand smoke (SHS) exposure to society. Design Prevalence-based, disease-specific cost-of-illness study. We used an epidemiological population-attributable risk method determine that can be attributed SHS exposure. Setting Taiwan. Participants All adult population aged 35 older. Primary outcome measures Direct healthcare expenditures spent for treating tobacco-related diseases, indirect mortality measured by value...
Abstract Background International guidelines recommend ivosidenib followed by modified FOLFOX (mFOLFOX) for advanced intrahepatic cholangiocarcinoma (ICC) with isocitrate dehydrogenase 1 ( IDH1 ) mutations. Taiwan National Health Insurance covers only fluorouracil/leucovorin (5-FU/LV) chemotherapy this ICC group, and there has been no prior economic evaluation of ivosidenib. Therefore, we aimed to assess ivosidenib’s cost-effectiveness in previously treated, ICC-presenting mutations compared...
Venous thromboembolism (VTE) is a clinically significant complication that well documented among Caucasian cancer patients. However, evidence regarding VTE incidence and treatment Asian patients very limited. The objective of this study to investigate the incidence, risk factors management Taiwanese patients.Using Taiwan's National Health Insurance Research Database, we identified 43,855 newly diagnosed between 2001 2008. Two alternative algorithms for identifying event were explored better...
Nomograms incorporating multiple prognostic factors are useful for individualized estimation of survival in cancer patients. However, nomograms the prediction pathological complete response (pCR) after neoadjuvant chemoradiotherapy (nCRT) patients with esophageal scarce. Here, we describe development a nomogram predicting pCR nCRT squamous cell carcinoma (ESCC). We retrospectively reviewed records 392 ESCC who underwent followed by esophagectomy. Seventy percent participants (n = 274) were...
Abstract Background The current NCCN guidelines recommend considering elective neck dissection (END) for early‐stage oral cavity squamous cell carcinoma (OCSCC) with a depth of invasion (DOI) exceeding 3 mm. However, this DOI threshold, determined by evaluating the occult lymph node metastatic rate, lacks robust supporting evidence regarding its impact on patient outcomes. In nationwide study, we sought to explore specific indications END in patients diagnosed OCSCC at stage cT2N0M0, as...
The aim of this study was 2-fold: first, to assess the prognostic significance on overall survival (OS) 3-point tumor regression grade (TRG) in patients with esophageal squamous cell carcinoma (ESCC) who received neoadjuvant chemoradiotherapy (nCRT); second, investigate associations TRG clinicopathological characteristics patients. A total 357 ESCC were retrospectively enrolled. determined by assessing percentage viable residual cells (VRTC) resected specimens as follows: 1, 0% VRTC; 2, 1%...
Lymph node dissection (LND) along the left recurrent laryngeal nerve (RLN) is a technically challenging part of esophageal cancer surgery, especially after chemoradiotherapy (CRT). Robotic surgery holds promise to increase its safety and feasibility. The aim this study was describe single thoracoscopic surgeon's experience related transition from video-assisted esophagectomy (VATE) robotic (RE)-with special focus on RLN LND. Patients who underwent minimally invasive following CRT were...
(1) Background: The optimal cutoff value that maximizes the prognostic of surgical margins in patients with resected oral cavity squamous cell carcinoma has not yet been identified. (2) Methods: Data for this study were retrieved from Taiwan Cancer Registry Database. A total 13,768 Taiwanese identified and stratified according to different margin statuses (0, 0.1–4 > 4 mm). five-year local control, disease-specific survival overall rates main outcome measures. (3) Results: 5-year close (0...
Background: Thoracoscopic removal of small pulmonary nodules is traditionally accomplished through a two-step approach-with lesion localization in CT suite as the first step followed by an operating room second step. While advent hybrid rooms (HORs) has fostered our ability to offer more patient-tailored approach that allows simultaneous and within single-step, randomized controlled trials (RCTs) compared two techniques (two- vs. single-step) are still lacking. Methods: This RCT conducted...