A5100629597- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Peripheral Artery Disease Management
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Cerebrovascular and Carotid Artery Diseases
- Radiation Dose and Imaging
- Aortic aneurysm repair treatments
- Heart Failure Treatment and Management
- Venous Thromboembolism Diagnosis and Management
- Advanced MRI Techniques and Applications
- Advanced X-ray and CT Imaging
- Atrial Fibrillation Management and Outcomes
- Cardiac Structural Anomalies and Repair
- Diabetic Foot Ulcer Assessment and Management
- Dialysis and Renal Disease Management
- Angiogenesis and VEGF in Cancer
- Cardiovascular Disease and Adiposity
- Adipose Tissue and Metabolism
- Vascular Procedures and Complications
- Diagnosis and Treatment of Venous Diseases
- Hemodynamic Monitoring and Therapy
- Pericarditis and Cardiac Tamponade
Chang Gung University
2015-2025
Chang Gung Memorial Hospital
2015-2025
Linkou Chang Gung Memorial Hospital
2009-2024
Thrombolysis in Myocardial Infarction Study Group
2022
Weatherford College
2022
Memorial Hospital of South Bend
2011-2016
GTx (United States)
2012
Large cardiovascular outcome trials have reported favorable effects of sodium-glucose co-transporter 2 (SGLT2) inhibitors on heart failure. To study the potential mechanism SGLT2 inhibition in failure, we used murine doxorubicin-induced cardiomyopathy model and identified toll-like receptor 9 (TLR9), NAD-dependent deacetylase sirtuin-3 (SIRT3), Beclin 1, acting a complex together response to empagliflozin treatment. The interactions implications mitochondrial function were evaluated with...
The Taiwan Society of Cardiology (TSOC) and Plastic Surgery (TSPS) have collaborated to develop a joint consensus for the management patients with advanced vascular wounds. taskforce comprises experts including preventive cardiologists, interventionists, cardiovascular plastic surgeons. focuses on addressing challenges in diagnosing, treating, managing complex wounds; incorporates perfusion evaluation wound care team; highlights importance cross-disciplinary teamwork. aim this is manage...
In Taiwan, the incidence of non-ST segment elevation acute coronary syndrome (NSTE-ACS) continues to increase in recent years. The purpose this guideline is help health care professionals Taiwan use adequate tests and treatments for management NSTE-ACS. For rapid diagnosis, addition history physical examination, 0/3 h diagnosis protocol with high sensitivity cardiac troponin assay recommended guideline. Dual antiplatelet anticoagulation therapies are important parts initial treatment. Risk...
Background:Acute kidney injury (AKI) is associated with morality and repeated hospitalization, frequently encountered in patients acute decompensated heart failure (ADHF). However, few effective tools exist for early AKI identification risk stratification.Methods Results:This was a prospective observational study conducted the coronary care unit (CCU) of tertiary university hospital. Patients diagnosis ADHF who were using diuretics enrolled.Samples collected between December 2013 February...
Coronary artery disease is the leading cause of death worldwide. Conventional balloon angioplasty associated with high rates complications such as coronary dissection and vessel recoil. The deployment bare-metal stents (BMSs) can overcome these problems achieve a better patency rate than simple angioplasty. It has been shown that stent design including structure platform, size, length, strut thickness major influence on clinical results. Even though BMS implantation widely used in...
Abstract Background Asprosin is a novel fasting glucogenic adipokine discovered in 2016. induces rapid glucose releases from the liver. However, its molecular mechanisms and function are still unclear. Adaptation of energy substrates fatty acid to recently considered therapeutic target heart failure treatment. We hypothesized that asprosin able modulate cardiac mitochondrial functions has important prognostic implications dilated cardiomyopathy (DCM) patients. Methods prospectively enrolled...
Background: Invasive coronary angiography is the gold standard for assessing in-stent restenosis (ISR) in patients with artery disease. However, predictive value of non-invasive Tissue Doppler Imaging (TDI) to evaluate ISR has not been studied extensively. Methods: A total 41 (19 acute myocardial infarction and 22 stable angina pectoris) who received percutaneous intervention (PCI) were enrolled study. Time-to-peak velocities (TpV) 12 non-apical segments left ventricle, by pulse wave TDI...
Peripheral arterial disease (PAD) is a consequence of systemic atherosclerosis, resulting in narrowing and diminished blood flow, leading to complications like claudication, rest pain, ulcers, gangrene, functional limitations. Despite its impact on cardiovascular mortality, physical function, quality life, PAD has received less attention than other atherosclerotic disorders. This study addresses the paucity comprehensive clinical data Taiwan, aiming analyze incidence, risk factors,...
Recent studies have proven that initial renal dysfunction and worsening function during hospitalization can predict the clinical outcome of patients with acute myocardial infarction (AMI). There is limited study regarding kidney injury (AKI) by RIFLE classification (Risk failure, Injury to kidney, Failure function, Loss End-stage failure) assess AMI survivors.During a mean follow-up period 635.3 ± 204.9 days, 2-year mortality rate was 10.6% in 613 who survived discharge. Adjusted Cox...
This observational study aimed to determine whether the SYNergy between percutaneous coronary intervention (PCI) with TAXUS drug-eluting stent and cardiac surgery (SYNTAX) score can act as an independent predictor for death on long-term follow-up in patients acute ST-elevation myocardial infarction (STEMI).One hundred fifty-three admitted Chang Gung Memorial Hospital Linkou because of STEMI from 1 January 2008 31 December 2009, who subsequently underwent a primary PCI, were included this...
The prognostic value of homocysteine (HCY) in patients with coronary artery diseases (CAD) is still controversial. objective this study was to investigate whether elevated HCY level at admission predict long-term outcomes after percutaneous interventions (PCI) stenting.From the institutional registry Cardiovascular Atherosclerosis and Percutaneous TrAnsluminal INterventions (CAPTAIN), we enrolled a total 1,307 documented CAD undergone PCI bare metal stents from July 2003 December 2014. They...
Objective Little is known about long-term outcomes among patients who receive percutaneous angioplasty (PTA) for peripheral artery disease (PAD) then undergo below-knee or above-knee amputations. We sought to determine clinical associated with amputation, along possible explanatory factors and treatment strategies. Methods Using data from Taiwan's National Health Insurance Research Database 1997 2010, 7,568 adult were divided into three groups: lower extremity preserved (LE), amputation (BK)...
This study was designed to evaluate the acute and long-term clinical angiographic outcomes of drug-eluting stent (DES) implantations in aorto-ostial, left anterior descending artery (LAD)-ostial nonostial lesions.From CAPTAIN (cardiovascular atherosclerosis percutaneous transluminal interventions) registry, a total 61 patients with 173 LAD-ostial, 1,954 2,391 lesions were treated DES implantations.Compared LAD-ostial lesions, those aorto-ostial had larger late loss (0.43 ± 0.66, 0.42 0.63,...
When acute aortic dissection is complicated with myocardial infarction, the diagnosis of can be problematic. In these cases, patients might treated primary percutaneous coronary intervention (PCI) and suffer acatastrophic outcome. However, there are few reports or algorithm to facilitate accurate management this clinical situation.We evaluated 385 consecutive who underwent PCI arising from an initial STEMI at our hospitalbetween January 2006 March 2011. Clinical characteristics, angiographic...