A5001537388- Aortic aneurysm repair treatments
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Aortic Disease and Treatment Approaches
- Transplantation: Methods and Outcomes
- Vascular Procedures and Complications
- Cardiac Valve Diseases and Treatments
- Infectious Aortic and Vascular Conditions
- Cardiac, Anesthesia and Surgical Outcomes
- Renal Transplantation Outcomes and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac Arrest and Resuscitation
- Peripheral Artery Disease Management
- Organ Transplantation Techniques and Outcomes
- Congenital Heart Disease Studies
- Venous Thromboembolism Diagnosis and Management
- Diagnosis and Treatment of Venous Diseases
- Cerebrovascular and Carotid Artery Diseases
- Viral Infections and Immunology Research
- Cardiac and Coronary Surgery Techniques
- Cardiac tumors and thrombi
- Polyomavirus and related diseases
- Esophageal Cancer Research and Treatment
- Acute Ischemic Stroke Management
- Antimicrobial Peptides and Activities
University of Hong Kong
2025
National Taiwan University Hospital
2015-2024
National Taiwan University
2012-2024
National Yang Ming Chiao Tung University
2024
National Chiayi University
2020
National Kaohsiung University of Science and Technology
2019
Herbalife (Australia)
2019
Kaohsiung Medical University
2011-2013
Kaohsiung Medical University Chung-Ho Memorial Hospital
2011-2013
Taipei Veterans General Hospital
2011
Impaired wound healing frequently occurs in patients with diabetes. Interleukin (IL)-8 production by keratinocyte is responsible for recruiting neutrophils during healing. Intense inflammation associated diabetic wounds, while reduction of neutrophil infiltration enhanced We hypothesized that increased recruitment keratinocytes may contribute to the delayed wounds. Using cultured human and a rat model, current study shows high-glucose environment IL-8 via epidermal growth factor receptor...
In Brief Purpose To determine the safety and efficacy of small interfering RNA (siRNA) directed against vascular endothelial growth factor (VEGF) in a nonhuman primate model laser-induced choroidal neovascularization (CNV). Methods Each animal received laser rupture Bruch's membrane to induce CNV both eyes. was then randomized receive 0.05 mL either vehicle alone or VEGF siRNA at 70 μg, 150 350 μg eyes by intravitreal injection. Eyes were monitored weekly ophthalmic examination, color...
The clinical implication of the coronary artery calcium score (CS) is well demonstrated. However, little known about association between lower extremity arterial calcification and outcomes.Eighty-two patients with symptomatic peripheral disease (age 61.0±12.4 years) were followed for 21±11 months. CSs, ranging from common iliac bifurcation to ankle area, analyzed through noncontrast multidetector computed tomography images retrospectively. primary endpoints this study amputation mortality....
The rate of detection small pulmonary nodules (SPNs) has increased. Thoracoscopic resection following image-guided localization had been a reliable alternative in their treatment. We present our experience with dye using robotic C-arm computed tomography (CT) followed by immediate video-assisted thoracoscopic surgery (VATS) for SPNs hybrid operating room (OR).From July 2015 to 2016, 25 consecutive patients smaller than 2 cm underwent CT-guided blue tattooing VATS OR. Their medical records...
The Taiwan Society of Cardiology (TSOC) and Plastic Surgery (TSPS) have collaborated to develop a joint consensus for the management patients with advanced vascular wounds. taskforce comprises experts including preventive cardiologists, interventionists, cardiovascular plastic surgeons. focuses on addressing challenges in diagnosing, treating, managing complex wounds; incorporates perfusion evaluation wound care team; highlights importance cross-disciplinary teamwork. aim this is manage...
Wound healing is a dynamic and complicated process in which inflammation, re-epithelialization angiogenesis play important roles. Intriguingly, all three processes have been found to be defective during diabetic wound conditions. One common denominator associated with regulation of these events human β-defensin-2 (hBD2). It has shown that skin wounding induces cutaneous hBD2 expression, wounds inadequate hBD expression.The current study was launched explore the effects high-glucose...
Ventricular septal rupture (VSR) is an uncommon but well-recognized mechanical complication of acute myocardial infarction (AMI). The outcome VSR remains poor even in the era reperfusion therapy. We reviewed our experience with surgical repair post-infarction and analyzed outcomes attempt to identify prognostic factors.
Diabetes mellitus is characterized by elevated plasma glucose and increased rates of skin infections. Altered immune responses have been suggested to contribute this prevalent complication, which involves microbial invasion. In study we explored the effects a high-glucose environment on innate immunity keratinocytes focusing β defensin-3 (BD3) using in vivo vitro models. Our results demonstrated that perilesional skins diabetic rats failed show enhanced BD3 expression after wounding....
Importance Vascular endothelial growth factor pathway inhibitors (VPIs) pose a concern for aortic aneurysm (AA) and dissection (AD), signaling potential vascular disease development. Objective To investigate VPI-associated AA AD. Design, Setting, Participants This case-control study with nested design used full population data from national claims database in Taiwan between 2011 2019. Eligible participants were aged 20 years or older kidney, hepatic, gastrointestinal, pancreatic cancer...
We developed a risk factor-scaling score (RFSS) to select which patients supported by extracorporeal membrane oxygenation (ECMO) were suitable for ventricular assist device (VAD) implantation or heart transplantation (HTx). A total of 78 with ECMO more than 48 h due cardiac origin included in this study. Patients categorized into two groups based on the outcomes: poor outcome group (n = 33) consisted those who later died excluded from VAD HTx; favorable 45) weaned off finally and survived...
Abstract Extracorporeal membrane oxygenation (ECMO) has been repeatedly used to rescue patients with cardiopulmonary arrest. However, its clinical utility in endocrine emergencies remains unclear. Herein, we describe a case series of 12 presenting refractory shock secondary who were rescued by ECMO support. Patients identified between 2005 and 2012 from our registry. The diagnostic distribution was as follows: pheochromocytoma crisis (n = 4), thyroid storm 5) diabetic ketoacidosis 3)....
Patients with acute (ACTBAD) or chronic complicated Type B aortic dissection (CCTBAD) undergoing thoracic endovascular repair (TEVAR) remain at high risk for late aorta-related events. Few data exist on the comparison of remodelling and outcomes after TEVAR between both groups.Forty-nine patients CCTBAD (n = 26) ACTBAD 23) were retrospectively reviewed our centre.The overall 30-day mortality was 4%. Cumulative freedom from all-cause (ACTBAD: 77.6%, CCTBAD: 68.8%; P 0.76), aneurysmal-related...
Purpose: To report our midterm results of the crossover chimney technique to preserve internal iliac artery (IIA) in patients with aortoiliac aneurysms (AIA) and isolated common (CIAA). Methods: Between May 2012 January 2014, 14 consecutive (mean age 77.3 years; all men) 17 AIA, CIAAs, or abdominal aortic short CIAs underwent elective endovascular aneurysm repair (EVAR) IIA. Follow-up assessment, including computed tomographic angiography duplex ultrasound, was performed at 1, 6, 12 months...