Background. esophageal cancer (ec) is one of the most aggressive malignancies gastrointestinal tract. chemoradiation therapy standard care for locally advanced ec. The purpose study was to evaluate efficacy given alone and in combination with surgery patients thoracic cancer. Material Methods . From January 1, 2012 december 31, 2021, a total 940 were registered regional registry, which 178 selected concurrent chemoradiotherapy (CRT) at clinical stages I–III. thirty seven who received CRT...

To create a prognostic model determining the risk of tension pneumothorax and need for intraoperative installation additional drainage after thoracoscopic lobectomy.

Background . Air-leak after lung resection is a common complication occurring in 30–50 % of patients immediately surgery. The prolonged air-leak (PAL) serious problem if it lasts more than 5 days surgery with the reported incidence 15 %. Despite progress thoracic including energy-based vessel-sealing devices and digital drainage systems, there no universal agreement on optimal treatment air-leaks. T he aim study : to improve postoperative outcomes PAL by optimization algorithm. Material...

The aim of the study is to identify risk factors for development postoperative cardiac and respiratory complications in patients after lobectomy develop nomograms predict such complications.
 Materials Methods. From January 2020 August 2023, 411 lobectomies were performed with non-small cell lung cancer surgical department thoracic oncology, Regional Clinical Oncology Dispensary (Ulyanovsk). present included 162 according designed enrolment criteria. authors identified statistically...

Background: This study aimed to assess the frequency of cervical anastomosis dislocation toward mediastinum after McKeown esophagectomy and significance this phenomenon for postoperative complications. Methods Results:The included 82 patients with stage I-III esophageal cancer who underwent surgical intervention using in a completely open version (thoracotomy, laparotomy, cervicotomy) or hybrid (thoracoscopy on right, cervicotomy).After esophagectomy, (DCA) posterior was noted 26.8%...

Uterine leiomyoma (ULM) is one of the most common gynecological pathologies in women reproductive age. The prevalence this pathology varies across different age groups, with approximately 10% 20–35 range, increasing to 40–45% after 35. ULM metastasis an extremely rare phenomenon, only 411 cases reported literature, including our 3 observations. Several definitions exist, being benign metastasizing ULM, found both domestic and foreign literature. Each observation crucial, as there are...

Purpose: To demonstrate treatment outcomes in two patients with small cell esophageal cancer. Cases reports. Patient M. was assigned to receive polychemotherapy (PC H) composed of etoposide 100 mg/ m2 intravenously on days 1 – 3 + cisplatin 80 mg/m2 day 1, every 21 for 6 cycles and lanreotide 120 mg subcutaneously, 28 days, followed by chemoradiotherapy (CRT). The patient received cycle PCT , which well tolerated. Then, the a 3D-conformal radiation therapy concurrently 2 chemotherapy: mg/m2....

Objective : to determine the frequency and risk factors for postoperative pancreatic fistula (POPF) after gastrectomy. Material Methods . From January 1, 2018 October 31, 2023, 198 patients with stage I–III gastric cancer underwent gastrectomy D2 lymphadenectomy at a Regional Oncological Dispensary. The characteristics of studied were assessed according unified protocol. Statistically significant influencing development POPF identified. Results incidence was 18.7 % (37/198). It found that...

For years, it has been the common and widely accepted practice in thoracic surgery to place apical basal drains after a lobectomy completely drain pleural cavity. With development of thoracoscopic technology, became apparent that use single chest tube provided same clinical results. However, sometimes tension pneumothorax occurs with need for additional drainage. The aim this study was develop prognostic model identify high risk patients intraoperatively insert drainage prevent...

The OBJECTIVE was to identify risk factors for anastomotic leakage following McKeown esophagectomy. METHODS AND MATERIALS . From January 1, 2016 December 31, 2022, in our clinic, a total of 69 patients with stage I–III esophageal cancer were operated esophagectomy performed fully open approach (thoracotomy, laparotomy, cervicotomy). characteristics the studied evaluated according standardized protocol. Statistically significant influencing development failure determined. RESULTS frequency...

Surgery is pivotal in treating esophageal cancer; hybrid esophagectomy, which combines minimally invasive and open techniques, shows promising outcomes. This historical cohort study compared the surgical outcomes of standard esophagectomy with esophagectomy. Overall, 58 patients who underwent either or at Ulyanovsk Regional Clinical Oncology Clinic, Russia, from January 2015 to December 2023 were included. Data on demographics, details, postoperative analyzed. The primary measures overall...

Purpose : to describe rare cases of orbital metastases from breast cancer. Material and Methods . Three Luminal A(1) B(2) cancer with were identified studied during the period 01.01.2018 01.05.2024. Metastasis orbit was detected 5, 2 1.5 years after radical mastectomy for Patients received chemotherapy radiation therapy. Results Cases metastasis originating found have a low frequency, but may be associated long between diagnosis initiation treatment. Early detection its active treatment...

The aim of the study is to determine incidence surgical site infection (SSI), risk factors for its development and evolve a prognostic model stratifying patients according level. Materials Methods. was conducted at Ulyanovsk Regional Clinical Hospital Oncology Center. A total 1,500 planned laparotomies were performed (database registration certificate No. 2024623300) including 190 gastrectomies with D2 lymph node dissection, 882 colon resections, 428 hysterectomies. retrospective analysis...

Introduction. For an extended period, numerous studies have been conducted to find the optimal treatment regimen for esophageal cancer. Chemoradiotherapy has demonstrated satisfactory results in of localized and locally advanced forms this disease. However, search best chemotherapy combination with radiotherapy remains a current focus many researchers. Aim. To evaluate effectiveness safety chemoradiotherapy (CRT) using FOLFOX patients Materials methods. A prospective study was at Ulyanovsk...

This article presents an assessment of the results surgical treatment benign formations and analysis these results.

Lung cancer is still the leading cause of death in oncologic patients, despite advances diagnosis and treatment. Objective. The aim study to examine immediate results pneumonectomy depending on various factors their influence incidence postoperative complications mortality. Materials Methods. A retrospective included 55 patients with non-small cell lung (NSCLC) who ubderwent surgical thoracic department Regional Clinical Oncology Center Ulyanovsk between January 1, 2016 December 31, 2017....

Primary gastric melanoma is an extremely rare disease. Melanoma of upper gastrointestinal tract usually occurs as metastasis from a primary skin tumor in 1 to 4 % cases. The paper describes case report female patient who received complex therapy at the State Healthcare Institution Ulyanovsk Regional Clinical Oncology Dispensary.

The aim of the study is to identify risk factors for development prolonged air leak in patients after lobectomy and construct a nomogram predict such complications.
 Materials Methods. Between January 2019 December 31, 2022, 417 lobectomies were performed with non-small cell lung cancer at Regional Clinical Oncological Dispensary Ulyanovsk. included 162 who thoroughly examined. Statistically significant influencing identified.
 Results. Multivariate logistic regression analysis...

Background: Lung cancer is one of the most common cancers in world.The main objective our study was to analyze results surgical treatment non-small cell lung (NSCLC) patients different age groups.Methods and Results: We examined 280 (262/93.6%men 18/6.4% women) aged from 39 75 years with NSCLC who underwent Ulyanovsk Regional Oncology Center period 2010 2016.The mean 64.9±10.1 years.Concomitant diseases were identified 256(91.4%)patients: cardiovascular 170(60.7%),chronic obstructive...

The article describes the observation of successful radical surgical treatment a giant gastrointestinal stromal tumor cardiac stomach in patient with concomitant pathology: type 2 diabetes mellitus, insulin-dependent, hypertensive disease stage 3, severe anemia.

Разработка и внедрение лимфотропного введения лекарственных препаратов как компонента комплексной послеоперационной терапии у пациентов с раком легкого является актуальной. Цель. Исследовать результаты комплексного послеоперационного лечения больных, оперированных по поводу рака легкого. Материалы методы. В послеоперационном периоде обследованы 280 в возрасте от 39 до 75 лет, период 2010 2016 г. Выполнялись пневмонэктомия или лоб- билобэктомия, лимфодиссекция. Пациенты были разделены на три...