A5073877763- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Lymphoma Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Research Studies
- Effects of Radiation Exposure
- Radiation Dose and Imaging
- Gastric Cancer Management and Outcomes
- Pituitary Gland Disorders and Treatments
- Esophageal Cancer Research and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Radiation Therapy and Dosimetry
- Cancer Immunotherapy and Biomarkers
- Childhood Cancer Survivors' Quality of Life
- Chemotherapy-induced cardiotoxicity and mitigation
- Viral-associated cancers and disorders
- Chronic Lymphocytic Leukemia Research
- Multiple and Secondary Primary Cancers
- Radiopharmaceutical Chemistry and Applications
- Adrenal Hormones and Disorders
- Thyroid Cancer Diagnosis and Treatment
- CNS Lymphoma Diagnosis and Treatment
- Brain Metastases and Treatment
- Artificial Intelligence in Healthcare and Education
Federal State Budgetary Institution Russian Scientific Center of Roentgenoradiology
2014-2024
Ministry of Health of the Russian Federation
2020-2022
Regional Center for Prevention and Control of AIDS and Infectious Diseases
2014
Background. Recently, the term 'dosiomics' has gained popularity in literature as a new direction radiomics. Dosiomics is texture analysis method that focuses on radiation dose distribution plans therapy. Most of published research field dosiomics focused predicting radiation-induced lung injury. Aim. To identify predictors injury using CT images. Materials and methods. The study used data from 36 patients with breast cancer who underwent postoperative conformal radiotherapy. were...
Lung cancer has the highest morbidity rate among all malignant tumors in men and mortality women Russia. In total, 49 145 new cases of lung were registered (diagnosed) Russia 2019. The majority are related to exogenic carcinogens mainly tobacco smoke. For several decades surgical resection with preoperative cytotoxic therapy was an optimal approach for maximal cure rate. This year recommendations updated strategies including adjuvant anti-PD-L1 atezolizumab following completion chemotherapy...
Clinical recommendations.
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To study clinical presentations and neuroimaging results in post chemotherapy encephalopathy.We examined 27 patients with cancer after (n=16) or chemoradiation (n=11).All complained of memory impairment, sluggish mentality, moderate headache, fatigue, sleep disorder, irritability. Their neurologic status included different organic symptoms. Post encephalopathy is characterized by the combination severe cerebral asthenia symptoms cephalgic syndrome. MRT showed single multiple loci gliosis...
Aim. To study the traditional risk factors for cardiovascular disease (CVD), indicators of endothelial function and exercise tolerance in patients received complex treatment cranial craniospinal tumors childhood, including radiation therapy. Material methods . We compared examination data 48 who underwent brain using irradiation childhood (mean age, 21,7±4,3 years, mean period after end treatment, 6,9±5,4 years), 20 healthy volunteers. Examination included assessment lipid profile, vascular...
BACKGROUND: The glucagon test (GT) is a promising alternative to the insulin hypoglycemia (IHT) in diagnosis of secondary adrenal insufficiency (SAI). AIM: To study feasibility using GT patients after craniospinal irradiation and determine cut-off value rule out SAI. METHODS: A total 28 (14 males 14 females) with median age 19 years (17; 23) who had undergone combination treatment (surgery, (35 Gy) boost tumor bed, polychemotherapy) extrapituitary brain tumors no later than 2 before...
BACKGROUND: In recent years, there has been a notable increase in the number of articles using term dosiomics. However, are no literature reviews on this topic Russian language.
 AIM: This study aims to describe basic principles dosiomics as derivative radiomics and analyze studies devoted assessing possibilities its application clinical practice.
 MATERIALS AND METHODS: A systematic search was performed PubMed database query OR dosiomic, eLibrary By April 2023, 43 foreign 1...
Objective : to develop a methodology for quantitative assessment of changes in density parameters pulmonary tissue on the basis dynamic CT data, which makes it possible assess presence dependence lung time elapsed after radiation therapy (RT), dose and volume irradiated tissue. Materials methods . Using data collected by 11 patients with malignant lymphomas, we developed new diagnostic technique analysis, is based analysis before RT areas selected range doses throughout volume. All received...
Objective: to reveal a relationship of lung changes time after radiotherapy (RT), its dose, and irradiated volume, by using new procedure quantitatively evaluate tissue density according the data dynamic X-ray computed tomography (X-ray CT) imaging. Subjects methods. Data on 29 cancer patients who had received RT chest area 3D planning, 2-5-Gy fractions, total focal dose 16 84 Gy in were retrospectively selected. Each patient underwent at least two CT studies (before RT); 83 analyzed. The...
Aim. The aim of our study was to analyze thyroid status in adult patients with Hodgkin’s lymphoma acute period after radiotherapy on neck region. Material and methods. Thyroid function (TSH, free T 4, anti-TPO) ultrasound were evaluated 22 adults (10 women, 12 men, mean age 30.2 yrs) a history (HL) before region, 7-14 days, 6 month, 1 year treatment. Results. Incidence subclinical hyperthyroidism 13.6% (7-14 days) There correlation between dose radiation incidence thyroiditis ( r = 0.67, p...
HIV-1 Infected Russian Children and Adolescents – a 24 Week Study Hedy Teppler, MD; Andrey Shuldyakov, Natalia Gankina, PhD; Valeriy Kulagin, Firaya Nagimova, Tatiana Shimonova, Dmitriy Sonin, Vladimir Sotnikov, Zakharova, Brenda Homony, MS; Deng Wang, Grigoriy Moshkovich, Merck Co., Inc., Whitehouse Station, NJ; Regional Center for Prevention Control of AIDS Infectious Diseases, Saratov, Russia; Krasnoyarsk, Clinical Krasnodar, Republican Kazan, Hospital #2 Moscow City Healthcare...
Лимфома Ходжкина (ЛХ) – пример реальных успехов современной медицины в лечении онкологических заболеваний. Эта смертельная прошлом болезнь настоящее время полностью излечивается у 80–90% больных, получавших терапию специализированных клиниках [4]. Достигнуты значительные успехи и реабилитации пациентов с ЛХ, что подтверждается результатами социологических исследований. По данным опросов, качество жизни излеченных больных не хуже, чем общей популяции [1, 5]. ЛХ относится к числу...
Postoperative radiation therapy (PORT) in the combined treatment of non-small cell lung cancer (NSCLC) can improve locoregional control disease regardless prevalence tumor and survival rates for IIA-IIIB stage NSCLC compared with surgical method alone. For more accurate assessment role PORT comparative analysis relapses structure after modality was carried out.
Objective: to comparatively analyze overall survival (OS) in patients with non-small cell lung cancer (NSCLC) affected lymph nodes (pN1) of the root after surgical and combination treatment postoperative radiotherapy (PORT). Subjects methods. OS was studied 310 grade 2-3 NSCLC. (pT1a-4N1M0): 101 lobectomy/bilobectomy, pulmonectomy ipsilateral mediastinal lymphadenectomy 209 similar volume hypofractionated PORT (a single focal dose (SFD) 3 Gy; 5 fractions per week, a cumulative (CFD) 36-39 Gy...
Objective . Comparison of the magnitude change in density lung tissue and volume these changes after radiation therapy over time based on data obtained using new method quantitative analysis developed by us with usual visual assessment CT data. Materials methods We used dynamic observation 90 patients who underwent RT for tumors thoracic localization during period from 2014 to 2021 at Federal Institution “Russian Scientific Center Roentgenoradiology”. These had examinations performed before...
Main idea of this article is to make a short overview modern MALT lymphoma treatment approaches. Historically, surgery was the leading modality. Discovery H.pylori involvement, invention new drugs and chemotherapy protocols, wide use monoclonal antibodies, significantly raised effectiveness conservative treatment. Routine CT scanning, conformal, precise radiotherapy techniques allowed achieve fine results, especially in case combined chemo – protocols. That why nowadays plays more...