P. Sh. Chomakhidze

ORCID: 0000-0003-1485-6072
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About
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Research Areas
  • Cardiac Imaging and Diagnostics
  • Advanced Chemical Sensor Technologies
  • Heart Rate Variability and Autonomic Control
  • Hemodynamic Monitoring and Therapy
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Cardiac, Anesthesia and Surgical Outcomes
  • ECG Monitoring and Analysis
  • Cardiovascular Function and Risk Factors
  • Non-Invasive Vital Sign Monitoring
  • Cardiac electrophysiology and arrhythmias
  • Coronary Interventions and Diagnostics
  • Blood Pressure and Hypertension Studies
  • Cardiovascular Health and Disease Prevention
  • Cancer Treatment and Pharmacology
  • Cardiac Arrhythmias and Treatments
  • Metabolomics and Mass Spectrometry Studies
  • Atrial Fibrillation Management and Outcomes
  • Cardiac pacing and defibrillation studies
  • Cardiac and Coronary Surgery Techniques
  • Meat and Animal Product Quality
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Pharmacology and Obesity Treatment
  • Hip and Femur Fractures
  • Cardiovascular and exercise physiology
  • Childhood Cancer Survivors' Quality of Life

Sechenov University
2016-2025

Research Institute for System Studies
2024

Institute of Cardiology
2020

Moscow Engineering Physics Institute
2016

The availability of simple, accurate, and affordable cuffless blood pressure (BP) devices has the potential to greatly increase compliance with measurement recommendations utilization BP measurements for telemonitoring. aim this study is evaluate correlation between findings from routine using a conventional sphygmomanometer results portable ECG monitor combined photoplethysmography (PPG) pulse wave registration in patients arterial hypertension. Methods: included 500 aged 32–88 years (mean...

10.3390/s21103525 article EN cc-by Sensors 2021-05-19

Ischemic heart disease (IHD) is a global health crisis exacerbated by diagnostic and preventive challenges. This study investigated associations between lipid profiles, inflammation biomarkers, exhaled volatile organic compounds (VOCs) in IHD using machine learning. Eighty participants (31 patients confirmed computed tomography perfusion [CTP]; 49 controls) underwent CTP, breath analysis (PTR-TOF-MS-1000), blood testing. LASSO regression with cross-validation analyzed links VOCs, parameters...

10.20944/preprints202502.1313.v1 preprint EN 2025-02-18

Cardiovascular disease (CVD) and associated sequalae remain the leading cause of disability worldwide. Ischemic heart (IHD) failure are most common etiologies morbidity mortality This is due to poor diagnostic management methods for IHD. Early detection related risk factors through modern strategies underestimated requires further research. To interpret data from published literature on volatile organic compounds (VOC), including all used analyze exhaled breath in patients with IHD failure....

10.4330/wjc.v17.i2.102851 article EN World Journal of Cardiology 2025-02-24

Anti-cancer treatment can be fraught with cardiovascular complications, which is the most common cause of death among oncological survivors. Without appropriate cardiomonitoring during anti-cancer treatment, it becomes challenging to detect early signs complications. In order achieve higher survival rates, necessary monitor patients outpatiently after administration. this regard, we aim evaluate efficacy single-lead ECG remote monitoring cardiotoxicity in cancer minimal diseases first cycle...

10.1016/j.ijcha.2024.101336 article EN cc-by-nc-nd IJC Heart & Vasculature 2024-01-20

Abstract Background Ischemic heart disease (IHD) has the highest mortality rate in globe. This returns to poor diagnostic and therapeutic strategies including early prevention methods. Aims To assess changes single channel electrocardiography (SCECG) at rest on exercise test patients with vs without IHD confirmed by stress computed tomography myocardial perfusion (CTP) imaging vasodilatation stress-test. Objectives frequently have preventable risk factors causes that lead appearance....

10.1101/2024.04.20.24306122 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2024-04-22

State-of-the-art therapy improves the five-year survival rate of patients under age 20 with cranial and craniospinal tumors by up to 74%. The urgency dealing effectively late treatment-associated cardiovascular complications is rising. Objective: We aimed assess echocardiographic parameters exercise performance in subjects a history complex treatment for childhood. Methods: study 48 who underwent irradiation CNS childhood healthy age- sex-matched volunteers was conducted. examination...

10.3390/jcm13113045 article EN Journal of Clinical Medicine 2024-05-22

Background Cardiopulmonary exercise testing (CPET) has shown to be useful for preoperative risk stratification in various types of intra-abdominal and thoracic surgery. However, data about the predictive value CPET cardiovascular outcome after gastric or oesophageal cancer surgery are inconclusive. The aim this study was evaluate prognostic parameters prediction complications patients with type Methods This is a prospective single-centre interventional cohort including 200 consecutive who...

10.1136/openhrt-2021-001932 article EN cc-by-nc Open Heart 2022-07-01

Aims: To investigate the potential of a signal processed by smartphone-case based on single lead electrocardiogram (ECG) for left ventricular diastolic dysfunction (LVDD) determination as screening method. Methods and Results: We included 446 subjects sample learning 259 patients test aged 39 to 74 years testing with 2D-echocardiography, tissue Doppler imaging ECG using monitor assessment LVDD. Spectral analysis signals (spECG) has been used in combination advanced processing artificial...

10.1177/11795468221120088 article EN cc-by-nc Clinical Medicine Insights Cardiology 2022-01-01

10.17116/kardio20169152-57 article EN Russian Journal of Cardiology and Cardiovascular Surgery 2016-01-01

Abstract Coronary artery disease is the leading cause of mortality worldwide, accounting for 12.8% all deaths. Although clinical benefits treating stenosis with percutaneous coronary intervention (PCI) have been extensively demonstrated, residual myocardial ischemia remains in about 30–50% patients even after a formally successful PCI. We apply previously developed and validated 1D model haemodynamics, which distributes terminal hydraulic resistance based on diameters parent vessels Murray’s...

10.1515/rnam-2022-0024 article EN Russian Journal of Numerical Analysis and Mathematical Modelling 2022-11-01

Objective. To evaluate the alterations of Global longitudinsl strain (GLS) and it’s value for prediction cardiotoxicity low to moderate cumulative doses anthracyclines. Methods. Forty-nine women 50 ± 10 years old with breast cancer, treated anthracyclines (cumulative dose 251 60 mg/m2) were enrolled in study. Echocardiography GLS measurement was performed at baseline, end anthracycline treatment, then every 3 months during 1 year. Cardiotoxicity defined as a decline left ventricular ejection...

10.33667/2078-5631-2022-33-19-26 article EN cc-by Medical alphabet 2023-01-12

Abstract In the present work, we construct a model of coronary flow, which utilizes both CT scans large arteries and perfusion. The describes pulsatile flow in patient’s network vessels takes into account number physiological effects: myocardium contractions, stenoses, impairment microvascular main novelty this is new smooth boundary conditions that have not been used before patient-specific simulations circulation. New use 0D lumped approach provide asymptotic convergence solution for cases...

10.1515/rnam-2023-0013 article EN Russian Journal of Numerical Analysis and Mathematical Modelling 2023-06-01

It would be useful to develop a reliable method for the cuffless measurement of blood pressure (BP), as such could made available anytime and anywhere effective screening monitoring arterial hypertension. The purpose this study is evaluate measurements through CardioQVARK device in clinical practice different patient groups.This involved 167 patients aged 31 88 years (mean 64.2 ± 7.8 years) with normal pressure, high compensated pressure. During each session, three routine intervals 30 s...

10.3390/pathophysiology30040042 article EN cc-by Pathophysiology 2023-12-01

<strong>Background:</strong> Screening for atrial fibrillation has the potential to significantly reduce cardiovascular morbidity and mortality. However, questions in regard how screen, on whom optimal setting of screening remain unanswered. <strong>Objective: </strong>To assess applicability a federal cardiac monitoring (AF) remote heart rhythm patients at high risk mixed urban rural population Russia. <strong>Methods:</strong> This is prospective multicenter cohort study including 3249...

10.5334/gh.1057 article EN cc-by Global Heart 2022-01-01

Evaluation of the value results use cardiac functional examination methods for stratification risk developing cardiovascular complications in planned abdominal surgical interventions patients over 65 years age or with pathology.The study included 179 a history heart disease who underwent elective surgery. The median was 70 years. During operation and 30 days after it, were recorded: severe (myocardial infarction, stroke, death from disease), others (strokes exertional angina, ischemic...

10.18087/cardio.2019.1.10210 article EN cc-by Kardiologiia 2019-01-28

Exhaled breath contains 1% of volatile organic compounds. The concentration individual biomarkers in hundreds compounds lies within the range ppm- ppb. In compare with control group concentrations acetone, acetic acid, ethanol, propylene is significantly higher HF-PEF group.

10.1088/1757-899x/151/1/012017 article EN IOP Conference Series Materials Science and Engineering 2016-10-01

Aim. To study the traditional risk factors for cardiovascular disease (CVD), indicators of endothelial function and exercise tolerance in patients received complex treatment cranial craniospinal tumors childhood, including radiation therapy. Material methods . We compared examination data 48 who underwent brain using irradiation childhood (mean age, 21,7±4,3 years, mean period after end treatment, 6,9±5,4 years), 20 healthy volunteers. Examination included assessment lipid profile, vascular...

10.15829/1560-4071-2022-5175 article EN cc-by Russian Journal of Cardiology 2022-12-08
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