A5025374944- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- ECG Monitoring and Analysis
- Heart Rate Variability and Autonomic Control
- Non-Invasive Vital Sign Monitoring
- Blood Pressure and Hypertension Studies
- Metabolomics and Mass Spectrometry Studies
- Advanced Chemical Sensor Technologies
- Atrial Fibrillation Management and Outcomes
- Acute Myocardial Infarction Research
- Cardiovascular Function and Risk Factors
- Hemodynamic Monitoring and Therapy
- Cancer, Lipids, and Metabolism
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Disease and Adiposity
- Cardiac Arrhythmias and Treatments
- Advanced MRI Techniques and Applications
- Cardiac pacing and defibrillation studies
- Meat and Animal Product Quality
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Adipokines, Inflammation, and Metabolic Diseases
- Thyroid Disorders and Treatments
- Cardiac Health and Mental Health
- MicroRNA in disease regulation
Sechenov University
2018-2025
Institute for Systems Analysis
2024
Russian Academy of Sciences
2024
The availability of simple, accurate, and affordable cuffless blood pressure (BP) devices has the potential to greatly increase compliance with measurement recommendations utilization BP measurements for telemonitoring. aim this study is evaluate correlation between findings from routine using a conventional sphygmomanometer results portable ECG monitor combined photoplethysmography (PPG) pulse wave registration in patients arterial hypertension. Methods: included 500 aged 32–88 years (mean...
Ischemic heart disease (IHD) is a global health crisis exacerbated by diagnostic and preventive challenges. This study investigated associations between lipid profiles, inflammation biomarkers, exhaled volatile organic compounds (VOCs) in IHD using machine learning. Eighty participants (31 patients confirmed computed tomography perfusion [CTP]; 49 controls) underwent CTP, breath analysis (PTR-TOF-MS-1000), blood testing. LASSO regression with cross-validation analyzed links VOCs, parameters...
Cardiovascular disease (CVD) and associated sequalae remain the leading cause of disability worldwide. Ischemic heart (IHD) failure are most common etiologies morbidity mortality This is due to poor diagnostic management methods for IHD. Early detection related risk factors through modern strategies underestimated requires further research. To interpret data from published literature on volatile organic compounds (VOC), including all used analyze exhaled breath in patients with IHD failure....
Background. Acute pericarditis is an inflammatory disease of the pericardium that requires timely and accurate diagnosis to prevent potentially dangerous complications. This article reviews key aspects treatment acute in real clinical practice. Due nonspecific picture absence special diagnostic methods, may cause difficulties. In about one third patients, course recurrent, which assessment possible risk factors for recurrent episodes pericarditis. The practice management patients with OP...
Background: Patients with metabolic syndrome (MS) tend to suffer from comorbidities, and are often simultaneously affected by obesity, dysglycemia, hypertension, dyslipidemia. This can be reversed if it is timely diagnosed treated a combination of risk factors-reducing lifestyle changes tailored pharmacological plan. Interval hypoxic-hyperoxic training (IHHT) has been shown as an effective program in reducing cardiovascular factors patients MS even the absence exercise. However, influence...
Non-coding RNAs reflect many biological processes in the human body, including athero-sclerosis. In a cardiology outpatient department cohort (N = 83), we aimed to compare levels of circulating microRNAs groups with vulnerable plaques 22), stable 23) and plaque-free 17) depending on coronary computed tomography angiography evaluate associations microRNA calculated cardiovascular risks (CVR), based SCORE2 (+OP), ACC/AHA, ATP-III MESA scales. Coronary was performed 640-slice scanner. Relative...
Anti-cancer treatment can be fraught with cardiovascular complications, which is the most common cause of death among oncological survivors. Without appropriate cardiomonitoring during anti-cancer treatment, it becomes challenging to detect early signs complications. In order achieve higher survival rates, necessary monitor patients outpatiently after administration. this regard, we aim evaluate efficacy single-lead ECG remote monitoring cardiotoxicity in cancer minimal diseases first cycle...
Abstract Background Ischemic heart disease (IHD) has the highest mortality rate in globe. This returns to poor diagnostic and therapeutic strategies including early prevention methods. Aims To assess changes single channel electrocardiography (SCECG) at rest on exercise test patients with vs without IHD confirmed by stress computed tomography myocardial perfusion (CTP) imaging vasodilatation stress-test. Objectives frequently have preventable risk factors causes that lead appearance....
Cystic fibrosis (CF) is a hereditary disease characterized by the progression of respiratory disorders, especially in adult patients. The purpose study was to identify volatile organic compounds (VOCs) as predictors dysfunction, chronic infections Staphylococcus aureus, Pseudomonas aeruginosa, Burkholderia cepacia, and VOCs associated with severe genotype highly effective modulator treatment (HEMT). Exhaled breath samples from 102 adults CF were analyzed using PTR-TOF-MS, obtained during...
Abstract In the present paper we construct model of coronary flow which utilizes patient’s CT data on both large CA and perfusion. We reconstruct vessels based extrude possibly invisible from branches left artery so that every terminal point supply standardized zone myocardium. apply a previously developed validated 1D haemodynamics. Utilizing patient-specific CTP for modifying outflow resistance at rest under stress conditions is major novelty work. From our results it follows acceptable...
Until recently, Russia did not utilize noninvasive fractional flow reserve (FFR) assessment. We developed an automated algorithm for assessment of FFR based on a one-dimensional (1D) mathematical modeling. The research aims to evaluate the diagnostic accuracy this algorithm. study enrolled 80 patients: 16 them underwent 64-slice computed tomography - included retrospectively, 64 prospectively, with 640-slice CT scan. Specialists processed images and evaluated FFR. Ischemia was confirmed if <...
Aims: To investigate the potential of a signal processed by smartphone-case based on single lead electrocardiogram (ECG) for left ventricular diastolic dysfunction (LVDD) determination as screening method. Methods and Results: We included 446 subjects sample learning 259 patients test aged 39 to 74 years testing with 2D-echocardiography, tissue Doppler imaging ECG using monitor assessment LVDD. Spectral analysis signals (spECG) has been used in combination advanced processing artificial...
Aim. To evaluate the diagnostic accuracy of a noninvasive method fractional flow reserve (FFR) assessment based on one-dimensional hemodynamic model build data obtained from coronary computed tomography angiography (CCTA). Material and methods. The study enrolled 57 patients: 16 them underwent 64-slice — included retrospectively, 34 prospectively, with 640-slice CT scan. Specialists Laboratory Mathematical Modeling processed images evaluated FFR. Ischemia was confirmed if FFR <0,80...
Aim. Hemodynamic shifts in the brain, developing due to carotid surgery (carotid endarterectomy or stenting) might be cause of perioperation strokes. Assessment for hemodynamic is important. The aim current study was develop methodics cerebral hemodynamics assessment at pre-operation and post-operation periods endarterectomy. Material methods. authors propose a mathematical model preoperation analysis changes extracranial regions brachiocephalic arteries after endarterctomy. development...
BACKGROUND Noninvasive assessment of the fractional flow reserve (FFR) in patients with coronary artery disease plays an important role determining need for revascularization. It is particularly relevant a borderline stenoses and painless myocardial ischemia. Our article describes first clinical experience Russian Federation using automated method noninvasive (FFRct) one-dimensional (1-D) mathematical model patient CASE REPORT A 58-year-old male who underwent stent implantation left...
It would be useful to develop a reliable method for the cuffless measurement of blood pressure (BP), as such could made available anytime and anywhere effective screening monitoring arterial hypertension. The purpose this study is evaluate measurements through CardioQVARK device in clinical practice different patient groups.This involved 167 patients aged 31 88 years (mean 64.2 ± 7.8 years) with normal pressure, high compensated pressure. During each session, three routine intervals 30 s...
<strong>Background:</strong> Screening for atrial fibrillation has the potential to significantly reduce cardiovascular morbidity and mortality. However, questions in regard how screen, on whom optimal setting of screening remain unanswered. <strong>Objective: </strong>To assess applicability a federal cardiac monitoring (AF) remote heart rhythm patients at high risk mixed urban rural population Russia. <strong>Methods:</strong> This is prospective multicenter cohort study including 3249...
Background: Determining the prognosis of heart failure with preserved ejection fraction (HFpEF) is problematic, as cannot be used. Formulae that estimate glomerular filtration rate (eGFR) may potential prognosticators for this condition, since renal dysfunction a well-known predictor poor outcomes all forms failure. Methods: A prospective observational study 117 HFpEF patients (average age 71.6±9.1 years; 65.8% women) who had eGFR determined after their first episode cardiac decompensation...
Aim. Comparative analysis of the diagnostic effectiveness onedimensional (1-D) and three-dimensional (3-D) non-invasive methods for coronary fractional flow reserve (FFR) assessment based on computed tomography angiography (CCTA). Material . We carried out a retrospective CCTA data 13 patients (men — 9, mean age 61,07±9,73). In original research, FFR those was evaluated using 3-D HeartFlow® Analysis followed by standard invasive assessment. estimated 1-D algorithm Laboratory Mathematical...
Aim. To determine the possible impact of anxiety and depression disorders on adherence patients with atrial fibrillation (AF) to anticoagulant rapy. Material methods . The study included outpatients AF any type. After signing informed consent, filled out questionnaires scales that determined level personal predisposition (MMAS-8, MMAS-4, SF-36, SHAI, STAI, HADS, NEO-FFI). Results A total 117 treated for were included. mean age was 74±5 years (men, 38%). Based MMAS-4 MMAS-8 results, adherent...
According to the World Health Organisation ischemic stroke is second leading cause of death in world. More frequent it caused by brachiocephalic arteries (BCA) atherosclerosis. Timely detection atherosclerosis and it`s unstable course can allow a timely response potentially dangerous changes reduce risk vascular complications. Omics technologies us identify new biomarkers that we use diagnosing diseases. The research included 90 blood plasma samples. first group - 52 patients with severe...