A5046943039- Cardiac Imaging and Diagnostics
- Gut microbiota and health
- Diet and metabolism studies
- Healthcare Systems and Public Health
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Health and Mental Health
- Neurological Disorders and Treatments
- Atrial Fibrillation Management and Outcomes
- Muscle Physiology and Disorders
- Vector-borne infectious diseases
- Circular RNAs in diseases
- Complementary and Alternative Medicine Studies
- Biotin and Related Studies
- Medication Adherence and Compliance
- Long-Term Effects of COVID-19
- Diabetes Treatment and Management
- Metabolomics and Mass Spectrometry Studies
- Natural Products and Biological Research
- Dietary Effects on Health
- Viral Infections and Immunology Research
- Lipoproteins and Cardiovascular Health
- Intensive Care Unit Cognitive Disorders
- Pulmonary Hypertension Research and Treatments
- Mechanical Circulatory Support Devices
- Migraine and Headache Studies
Federal State Budgetary Institution "Center for Expertise and Quality Control of Medical Care"
2022-2024
Sechenov University
2008-2019
Human immunodeficiency virus type 1 (HIV-1) infection and the consequent acquired syndrome (AIDS) has protean manifestations, including muscle wasting cardiomyopathy, which contribute to its high morbidity. The pathogenesis of these myopathies remains partially understood, may include nutritional deficiencies, biochemical abnormalities, inflammation, other mechanisms due viral replication. Growing evidence suggested that HIV-1-related proteins expressed by host in response infection, Tat...
Non-coding RNAs reflect many biological processes in the human body, including athero-sclerosis. In a cardiology outpatient department cohort (N = 83), we aimed to compare levels of circulating microRNAs groups with vulnerable plaques 22), stable 23) and plaque-free 17) depending on coronary computed tomography angiography evaluate associations microRNA calculated cardiovascular risks (CVR), based SCORE2 (+OP), ACC/AHA, ATP-III MESA scales. Coronary was performed 640-slice scanner. Relative...
РЕЗЮМЕ. Пандемия, вызванная COVID-19 затронула многие сферы нашей жизни, а последствия ее мы до сих пор разбираем и систематизируем. Постковидный синдром (последствия коронавирусной инфекции COVID-19, при которой 20 % людей, перенёсших коронавирусную инфекцию, страдают от долгосрочных симптомов, длящихся 12 недель в ряде случаев дольше) представляет собой глобальную угрозу для человека. Цель статьи - разобраться механизмах развития этих чтобы разработать эффективные профилактические...
Background: This study discusses the crucial factors responsible for progression of atherosclerotic cardiovascular disease (CVD). The interaction between gut microbiota, heart and vessels in CVD pathogenesis is extremely complex includes components such as direct bacterial translocation from to metabolitemediated damage. To a greater extent, seems be entangled with subtle immune system-to-microbiota interface. From among most significant advances recent years this area, it necessary...
The role of intestinal microbiota in aging and maintaining active longevity is considered. first part the article describes characteristics a healthy microbiome, its changes during aging, composition microbiome centenarians. importance high biodiversity emphasized. permeability new biomakers that assess condition (including zonulin) health development dysbiosis revealed. Separate groups microorganisms are associated with have been identified (such as Verrucomicrobia, which includes...
The role of intestinal microbiota in aging and maintaining active longevity is considered. second part examines the issues DNA damage by metabolites various bacteria, which increases risk cancer. interactions between immune system, connection dysbiosis indicating specific molecular mechanisms, are described detail. Particular attention paid to lymphocytes Th17 subpopulation. Changes microbiome that observed individuals with cardiovascular diseases (arterial hypertension, coronary heart...
Aim: To present the ARILIS study aimed at assessing use of artificial intelligence to analyze chest computed tomography (CT) data predict and prevent non-cancer mortality in patients with cancer. Material methods: This cohort will include cancer diagnosed Arkhangelsk region (AR) within 2019–2023 period. The COVID-19 pneumonia, general medical conditions, population Know Your Heart Study are planned be enrolled as control groups. detect quantify CT signs cardiovascular, pulmonary, bone...
Modern strategies of primary prevention cardiovascular complications atherosclerotic etiology are presented in this article: traditional approach based on assessment risk development complication and coming to replace it concept direct application results prospective clinical studies. The article contains detailed presentation new opportunities computer tomography the heart allowing substantially elevate precision etiology. Main attention is paid coronary artery calcification index, which...
To date, the prophylactic treatment of migraine has included only nonspecific drugs various pharmacological groups: beta-blockers propranolol and metoprolol, anticonvulsants topiramate valproic acid, antidepressants amitriptyline venlafaxine, candesartan, Ona botulinum toxin A. As these were developed for other diseases, their use was associated with adverse effects: decreased blood pressure, mental retardation, weight increase, nausea, some others. CGRP is a neuropeptide that regarded as...
The aim of study was to investigate atrial contractile function in patients with paroxysmal fibrillation (AF) sinus rhythm using transthoracic echocardiography.35 AF and arterial hypertension (mean age 62 ± 10 years, 43% males) were enrolled the study. Control group composed comparable without heart disturbances. We found significant depression contraction expressed as decrease left atrium EF, A' velocity VTI, increase A/A' ratio, whereas peak a not affected. Patients has markedly depressed...
To analyze the structure of expenses associated with warfarin dose adjustment and consequent international normalized ratio (INR) monitoring for effective stroke prevention in patients atrial fibrillation. The present study was designed as cost illness analysis. Expenses INR were calculated four different circumstances: 1) obligatory medical insurance system according current general tariff agreement; 2) managed outpatient department University hospital using prices consultations coagulation...
Objective To assess the prevalence and structure of non-adherence in Russian population patients with advanced atherosclerosis. Methods Sixty (mean age was 69±11 yrs, 30 males) cerebral arteriosclerosis ischemic heart disease were randomly selected from cardiovascular department enrolled study for subsequent psychiatric counseling, questionnaires MRI procedures. Patients stoke, focal neurological deficit any disorders anamnesis excluded. Results We have shown that 80% decreased or completely...