A5032657346- Atrial Fibrillation Management and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Acute Myocardial Infarction Research
- Venous Thromboembolism Diagnosis and Management
- Chronic Kidney Disease and Diabetes
- Chemical Thermodynamics and Molecular Structure
- Thermal and Kinetic Analysis
- Heart Failure Treatment and Management
- Lanthanide and Transition Metal Complexes
- Cardiovascular Function and Risk Factors
Sechenov University
2019-2023
Objective: This study’s objective was to evaluate the effects of pharmacokinetic and pharmacogenetic factors on major bleeding in patients with ACS non-valvular AF receiving combined antithrombotic therapy consisting rivaroxaban, clopidogrel, aspirin as part dual or triple therapy. Methods: A prospective observational study conducted two PCI centers Moscow, Russian Federation, from 2017 2018. One hundred were enrolled. Prospective follow-ups continued for 12 months. Results: total 36...
Introduction: The aim of this study is to assess the influence gene CYP2C19, CYP3A4, CYP3A5 and ABCB1 polymorphisms on clopidogrel antiplatelet activity, rivaroxaban concentration equilibrium, clinical outcomes among patients with acute coronary syndrome non-valvular atrial fibrillation. Methods: In multicenter prospective registry efficacy safety a combined antithrombotic therapy 103 fibrillation both undergoing or not percutaneous intervention were enrolled. trial assessed primary (major...
Purpose: To assess the prevalence of atrial fibrillation (AF) and use antithrombotic agents in adult patients with acute coronary syndrome (ACS). Materials Methods. We consecutively enrolled all ACS (n=1155) who were hospitalized two Moscowbased percutaneous intervention centers (each center performs over 500 PCIs a year) between October 2017 February 2018. AF was diagnosed 204 (17.7%). The risk thromboembolic complications assessed using CHA2DS2-VASc Score. hemorrhagic HAS-BLED data...
Background: Determining the prognosis of heart failure with preserved ejection fraction (HFpEF) is problematic, as cannot be used. Formulae that estimate glomerular filtration rate (eGFR) may potential prognosticators for this condition, since renal dysfunction a well-known predictor poor outcomes all forms failure. Methods: A prospective observational study 117 HFpEF patients (average age 71.6±9.1 years; 65.8% women) who had eGFR determined after their first episode cardiac decompensation...
.
Aim To evaluate outcomes in patients with acute coronary syndrome and atrial fibrillation who receive rivaroxaban the patients’ compliance antithrombotic therapy. Material methods The study was performed from October 2017 through December 2019 included 129 patients. Events between discharge hospital 12 months of follow-up were recorded. primary endpoint development major, minor or requiring medical attention bleeding according to TIMI scale. secondary a combination recurrent myocardial...