A5031236551- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Chemotherapy-induced cardiotoxicity and mitigation
- Gut microbiota and health
- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- SARS-CoV-2 and COVID-19 Research
- Gastroesophageal reflux and treatments
- Gastrointestinal Bleeding Diagnosis and Treatment
- Childhood Cancer Survivors' Quality of Life
- Electron Spin Resonance Studies
- Cancer-related cognitive impairment studies
- Gastrointestinal motility and disorders
- Pharmacological Effects of Natural Compounds
- Eosinophilic Esophagitis
- Diet and metabolism studies
- Neuroblastoma Research and Treatments
- Clostridium difficile and Clostridium perfringens research
- Contact Dermatitis and Allergies
- Thyroid Cancer Diagnosis and Treatment
- Congenital Anomalies and Fetal Surgery
- Esophageal and GI Pathology
- Pituitary Gland Disorders and Treatments
- Thyroid Disorders and Treatments
Sechenov University
2021-2025
Gut dysbiosis and subclinical intestinal damage are common in cirrhosis. The aim of this study was to examine the association biomarkers (diamine oxidase [DAO], claudin 3, fatty acid binding protein [I-FABP; FABP2]) with state gut microbiota blood levels DAO were inversely correlated lipopolysaccharide (LPS), presepsin, TNF-α, severity cirrhosis according Child–Pugh scores. level I-FABP directly 3 but not that DAO. Patients small bacterial overgrowth (SIBO) had lower than patients without...
Background . The allergic diseases are growing everywhere. exact diagnosis of allergens becomes more and critical because it significantly affects the further treatment patient, including question about using allergen-specific immunotherapy. There several laboratory instrumental tests among which skin most available. Despite its low cost, this method is characterized by a large percentage false-positive and, importantly, false-negative results. In addition, that can be detected limited. Aim....
The aim was to evaluate the relationship between gut dysbiosis and hemodynamic changes (hyperdynamic circulation) in cirrhosis, complications of this disease. This study included 47 patients with cirrhosis. Stool microbiome assessed using 16S rRNA gene sequencing. Echocardiography a simultaneous assessment blood pressure heart rate performed assess systemic hemodynamics. Patients hyperdynamic circulation had more severe lower albumin, sodium prothrombin levels, higher C-reactive protein,...
Anti-cancer treatment can be fraught with cardiovascular complications, which is the most common cause of death among oncological survivors. Without appropriate cardiomonitoring during anti-cancer treatment, it becomes challenging to detect early signs complications. In order achieve higher survival rates, necessary monitor patients outpatiently after administration. this regard, we aim evaluate efficacy single-lead ECG remote monitoring cardiotoxicity in cancer minimal diseases first cycle...
Background: Cytokine release syndrome is a serious complication of the new coronavirus infection .The aim study was to assess effectiveness and safety IL-17 antagonist nekatimab for its treatment.Methods: The retrospective included COVID-19 patients with C-reactive protein levels >60 mg/L.Patients received either netakimab (group NET), IL-6 tocilizumab TOC) or no anti-cytokine treatment CON).Results: Forty-four were enrolled in NET group, 27 TOC 47 CON group.Mortality lower group than groups...
Diarrhea is one of the manifestations novel coronavirus disease (COVID-19), but it also develops as a complication massive antibiotic therapy in this disease. This study aimed to compare these types diarrhea.We included patients with COVID-19 cohort and excluded chronic diarrhea, laxative use, those who died during first day hospitalization.There were 89 (9.3%), 161 (16.7%), 731 (75.7%) early viral, late antibiotic-associated, without respectively. Late diarrhea lasted longer (6 [4-10] vs 5...
State-of-the-art therapy improves the five-year survival rate of patients under age 20 with cranial and craniospinal tumors by up to 74%. The urgency dealing effectively late treatment-associated cardiovascular complications is rising. Objective: We aimed assess echocardiographic parameters exercise performance in subjects a history complex treatment for childhood. Methods: study 48 who underwent irradiation CNS childhood healthy age- sex-matched volunteers was conducted. examination...
Background and Aims: Gut dysbiosis abnormal cytokine profiles are common in cirrhosis.This study aimed to evaluate the correlations between them.Methods: In blood plasma of cirrhosis patients controls, 27 cytokines were examined using a multiplex assay.The levels nitrites (stable metabolites endothelial dysfunction biomarker nitric oxide) lipopolysaccharide (LPS) examined.The fecal microbiota was assessed by 16S rRNA gene sequencing.Results: Levels IL-1b, IL-2, IL-6, IL-13, IP-10, IFN-g,...
Allgrove syndrome is a rare autosomal recessive disorder characterized by the achalasia, alacrimia, adrenal insufficiency, which gave additional and more recognizable name of this pathology – “Triple-A syndrome”. The clinical presentation classical signs symptoms dependent on age patient. Ophthalmological abnormalities are usually present at birth, whereas gastrointestinal apparent after six months to first decade life. Neurological dysfunction from involvement central or autonomic nervous...
The aim is to study impact of vaccination against the novel coronavirus disease (COVID-19) with Sputnik V on mortality during period predominance delta variant SARS-CoV-2.This was a retrospective cohort individuals state health insurance at Moscow Ambulatory Center. cohorts included 41,444 persons vaccinated V, 15,566 survivors COVID-19, and 71,377 non-immune persons. deaths patients that occurred from June 1, 2021, August 31, were analyzed.Overall (0.39 % vs. 1.92 %; p < 0.001),...
Характеристика аллергенов кошки1 Федеральное государственное автономное образовательное учреждение высшего образования «Первый Московский государственный медицинский университет
Serum thyroglobulin is the main biomarker for postoperative monitoring of papillary thyroid cancer recurrence however, high prevalence disease dictates need to find a reliable indicator laboratory diagnosis tumor process. The presence antibodies affects prognosis and determines likelihood relapse; it impossible influence level using currently available methods. More commonly, trends in anti-thyroglobulin levels at time detection after radical treatment are considered, but there disagreement...
Aim. To study the significance of monitoring high-sensitivity troponin I (hs-cTnI) for predicting anthracycline-induced left ventricular (LV) dysfunction in treatment breast cancer patients with moderate and low risk cardiotoxicity (CT). Material methods . The involved 49 aged 50±10 years who underwent neoadjuvant or adjuvant chemotherapy, which included doxorubicin at a course dose 60 mg/m 2 an average cumulative 251±60 level hs-cTnI was determined by ultrasensitive method before start...
July 14, 2021 marks the 220th anniversary of an outstanding scientist and physician — Johann Peter Müller. It is thanks to his works that we know what «endocrine gland» is, understand taxonomy animal world essence ontogenesis. Professor, researcher, wonderful teacher, director anatomical physiological museum University Berlin he succeeded in any role life. Mueller’s discoveries were recognized during lifetime, textbooks published under leadership, scientific articles published. The value...