A5079418149- Healthcare Systems and Public Health
- Neurological Disorders and Treatments
- Cardiac Health and Mental Health
- Blood Pressure and Hypertension Studies
- Medication Adherence and Compliance
- Pharmaceutical Economics and Policy
- Lipoproteins and Cardiovascular Health
- Acute Ischemic Stroke Management
- Pharmaceutical Practices and Patient Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Acute Myocardial Infarction Research
- Hormonal Regulation and Hypertension
- Atrial Fibrillation Management and Outcomes
- Pharmacology and Obesity Treatment
- Antiplatelet Therapy and Cardiovascular Diseases
- Pharmaceutical industry and healthcare
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Cardiac Imaging and Diagnostics
- Heart Failure Treatment and Management
- Liver Disease Diagnosis and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Pharmaceutical studies and practices
- Cardiovascular Function and Risk Factors
- Health and Medical Research Impacts
National Research Center for Preventive Medicine
2015-2025
Ministry of Health of the Russian Federation
2005-2024
Sechenov University
2012-2014
Federal Agency for Health and Social Development
2005-2007
Создание руководства поддержано Советом по терапевтическим наукам отделения клинической медицины Российской академии наук.
International experience in implementing specialized programs into clinical practice — that assist healthcare professionals applying evidence-based treatment outlined guidelines (CG) confirms the effectiveness of this approach. It demonstrates significant, sustained improvement quality, improved outcomes, and reduced adverse events. An integral part such are special tools (indices, checklists, scales) enable evaluation including pharmacotherapy (PhT), monitoring adherence to CG. Since 2018,...
Aim. To evaluate the frequency and characteristics of self-medication in patients with cardiovascular diseases within Chuvashia Inappropriate Prescribing Study (CHIP) Registry. Material methods. The CHIP study is a cross- sectional study, which consistently included over age 50 who applied to cardiologist at outpatient clinic Republican Cardiological Dispensary. Exclusion criteria: presence mental illnesses, oncological detected less than 5 years ago, acute disorders 6 months prior...
The article presents the main goals, tasks, principles, and methodological aspects of cardiology register development. authors describe types registers, provide examples, specify key principles development maintenance. In addition, they discuss role both long- short-term registers in solving a wide range important research particularly areas effectiveness safety cardiovascular pharmacotherapy survival prognosis for specific nosological forms. task-specific limitations are also discussed.
The article describes the basic rules for conducting observational studies, in particular, registers. principles of assessment its quality and impact on results are discussed. potential evaluating therapeutic effect side effects randomized controlled trials (RCTs) studies is compared. Effects one drug identified RCTs
The treatment adherence problem is one of the most significant for medicine and society. article focuses on main aspects problem: modern view terminology this issue, various factors classification influencing adherence, diagnostics adherence. A review presented ways to improve that are provided by science apply into clinical practice. necessity confirmed, consider issues related with obligatory taking quality such therapy, as only high can be, being adhered, successful in goals: improvement...
One of the most common tests for evaluating medication adherence – 4-question scale Moriscos-Green is considered. Advantages (flexibility, conciseness) and disadvantages (insufficient sensitivity specificity) this test are presented. Disadvantages version were considered by authors in development a new (8-question) to assess adherence. The latest Moriscos has high fairly good specificity. versatility confirmed studies. Preference use shown screening assessment patients with various chronic...
Aim . To assess long-term outcomes within 12 months after hospital treatment of patients with coronavirus disease 2019 (COVID-19) as part a prospective registry. Material and methods. Outcomes in the posthospital period were assessed 827 diagnosed COVID-19 (age, 58,0±14,8 years; men, 51,3%). For periods 30-60 days, 6 discharge from hospital, cases death, nonfatal myocardial infarction (MI) stroke, hospitalization, acute respiratory viral infections/influenza assessed. The follow-up was...
Aim. To assess the characteristics of patients and short-term outcomes disease in hospitalized for cerebral stroke (CS) based on REGION-Moscow register. Material methods . From 2012 to 2017, 900 were included register, who consecutively admitted one clinics Moscow, whom CS or transient ischemic attack (TIA) diagnosed during hospitalization. Results. The average age entire cohort was 71±15 years. Women 59,4%, men — 40,6%. women 7 years more than men. Cardiovascular risk factors a combination...
The problem of medication adherence is still relevant, and the search for a reliable method its diagnosis continues. One most convenient promising ways to assess adherence, both in research actual clinical practice, use various questionnaires scores. Currently, several dozen different scores are presented Russia other countries. All them indirect methods assessment characterized by subjectivity. article presents data on famous widely used foreign scales (the 4- 8-item Morisky Medication...
Aim. To characterize patients admitted to hospital with suspected or documented COVID-19 infection and community-acquired pneumonia (CAP) assess the prevalence of concomitant cardiovascular, non-cardiac diseases, prehospital cardiovascular therapy outcomes in-hospital treatment. Material methods. The TARGET-VIP registry includes N. I. Pirogov National Medical Surgical Center and/or CAP for period from April 6, 2020 July 2, 2020. was diagnosed using polymerase chain reaction (PCR) tests chest...
Aim. Development, testing and validation of the original questionnaire “Adherence Scale” (AS) in PRIORITY ANTEY observational studies (OS). Materials methods. The OS assessed adherence to statins 298 patients with high very cardiovascular risk for 3 months. oral anticoagulants 201 non-valvular atrial fibrillation 1 year. Adherence was using AS questionnaire, which external performed (with calculation Cohen's Kappa coefficient). reference methods were validated direct medical interview. And...
The review is devoted to a modern problem of polypharmacy. A universal definition and clear criteria for this concept have not yet been formed, but it believed that the prescribing at least 5 medications (M). article discusses frequency main causes polypharmacy, demonstrates its relationship with age. presence overweight obesity, multimorbidity, low physical activity, fragility are clearly associated Cognitive impairment, disability, long-term pain syndrome malignant diseases also predispose...
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The objective was to assess patients' awareness of cardiovascular disease, its risk factors, and association with attendance at outpatient clinics in patients acute coronary syndrome (ACS).
<h3>ЦЕЛЬ ИССЛЕДОВАНИЯ</h3> Описать методологию создания и первые результаты проспективного госпитального регистра пациентов с предполагаемыми или подтвержденными коронавирусной инфекцией (COVID-19) внебольничной пневмонией (ТАРГЕТ-ВИП). <h3>МАТЕРИАЛ И МЕТОДЫ</h3> В регистр ТАРГЕТ-ВИП включены все больные, госпитализированные в НМХЦ им Н.И. Пирогова 06.04.20 по 02.07.20 пневмонией. Источник данных о больных — электронная медицинская документация. Кроме того, на госпитальном этапе либо 30 сут...
Aim. To study the compliance of patients to visits in outpatient institutions (OI) with data from acute coronary syndrome registry (ACS) LIS-3, prior ACS development, and evaluate quality pre-hospital therapy among different compliance. Material methods. Patients (n=320), hospitalized toLubertsyDistrictHospital№2 ACS, were selected 3 groups depending on OI visiting before ACS: group A — compliant (n=139); B partially compliant; C non-compliant (n=78). score invented for assessment...
Aim. To study adherence to treatment with new oral anticoagulants (NOAC) and factors associated it in patients non-valvular atrial fibrillation (AF) within the outpatient PROFILE registry. Material methods. ANTEY included 201 AF from registry (89.3%): 118 males (58.7%) 83 females (41.3%), aged 71.1Ѓ}8.7 years. The consisted of two visits half a year apart (V0, V1) phone contact (PC) one after V0. During V0 all were recommended start therapy NOACs. Adherence was assessed during use original...
Aim. To assess the patients' pharmacotherapy preceding acute myocardial infarction (AMI) and to effects of this therapy on hospital mortality. Material methods. 1133 patients were enrolled into LIS AMI register . All these experienced leading admitting in territory one districts Moscow Region during 3 years. The that received before was analyzed as well influence different drugs mortality risk. Results. 172 (15.2%) died hospital. Before admission 21.4% β-blockers, 35.3% — ACE inhibitors,...
Aim. Estimation of social, demographic and anamnestic characteristics patients survived cerebral stroke as well the medical treatment received by before reference in hospital at discharge within framework register LIS-2 (study mortality among Lyubertsy district). Material methods. All (637 persons) admitted to regional №2 due from 01.01.2009 31.12.2010 were enrolled into study. Results. 36% men 64% women with mean age 70.99 Ѓ }9.6 years old. 554 (87.0%) had history arterial hypertension 155...
Aim. To research the prevalence of atrial fibrillation (AF) and to compare clinical characteristics patients those without AF. Material methods. At moment cross-section Profile Study included 671 with various cardiovascular diseases, who consulted at Preventive pharmacotherapy department Centre. Results. AF was diagnosed in 99 (14,7%). There no difference by gender AF, but they were significantly older. common risk factors, ischemic heart disease peripheral atherosclerotic disease. Anamnesis...
Aim. To assess the potential of ursodeoxycholic acid (UDCA) in prevention liver dysfunction patients with cardiovascular diseases (CVD) and high risk events (CVE) indications for statins use. Material methods. Patients (n=262, age 60.1±8.9 years) took secondary CVE observational cohort study. The follow-up duration was 6 months. UDCA recommended all because and/or biliary tract. Some treatment compliance strictly followed recommendations to take UDCA, another part low did not UDCA....
Aim. To assess the main features of clinical course acute cerebrovascular accident (ACVA), its short-term and long-term outcomes quality pharmacotherapy based on hospital register. Material methods. The register stroke (AS) was organized in one cardiovascular centers Moscow city. results pilot part study are presented (170 patients hospitalized from January 01, 2014 to September 30, with ACVA living service area closest outpatient clinics). Presence diseases (CVD) their risk factors (RF),...