- Lipoproteins and Cardiovascular Health
- Gallbladder and Bile Duct Disorders
- Liver Disease Diagnosis and Treatment
- Economic and Technological Developments in Russia
- Pancreatitis Pathology and Treatment
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Lipid metabolism and disorders
- Systemic Lupus Erythematosus Research
- Sepsis Diagnosis and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Respiratory Support and Mechanisms
- Pharmaceutical Economics and Policy
- Trace Elements in Health
- Heavy Metal Exposure and Toxicity
- SARS-CoV-2 and COVID-19 Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Coronary Interventions and Diagnostics
- Economic Development and Digital Transformation
- Aluminum toxicity and tolerance in plants and animals
- Pancreatic and Hepatic Oncology Research
- COVID-19 Clinical Research Studies
- Liver Disease and Transplantation
- Genomics and Rare Diseases
- Regional Economic Development and Innovation
- Statistical and Computational Modeling
National Medical Research Center of Cardiology
2020-2024
North-Western State Medical University named after I.I. Mechnikov
2016-2023
S. M. Kirov Military Medical Academy
2014-2021
Vladimir State University
2021
National Statistical Service of the Republic of Armenia
2020
The Russian Presidential Academy of National Economy and Public Administration
2020
Military University
2020
The Russian Society of Cardiology (RKO) With the participation of: National for Study Atherosclerosis (NOA), Association Endocrinologists (RAE), Cardiosomatic Rehabilitation and Secondary Prevention (RosOKR), Scientific Medical Therapists (RNMOT), Eurasian Cardiologists, (EAT), Gerontologists Geriatricians
Disclaimer РThe EAC/RNAS Guidelines represent the views of EAC and RNAS, were produced after careful consideration scientific medical knowledge, evidence available at time their publication. The RNAS is not responsible in event any contradiction, discrepancy, and/or ambiguity between other official recommendations or guidelines issued by relevant public health authorities, particular relation to good use healthcare therapeutic strategies. Health professionals are encouraged take fully into...
Aim. Russian multicenter register of familial hypercholesterolemia (FH) was transformed into Register patients with FH and very high cardiovascular risk insufficient effect hypolipidemic therapy (RENESSANS Registry) in 2017 The aim RENESSANS maximal inclusion not only FH, but also those atherosclerotic diseases (CVD), who did achieve targeted level low density lipoprotein cholesterol (LDL-C) using drug therapy. Material methods. Registry is an open, national, observing study that includes...
The article provides the main statements of guidelines for anesthesia and intensive care patients with coronavirus disease (COVID-19), developed by Federation Anesthesiologists Reanimatologists Russia. In process developing recommendations, publications official websites Russian Federation, electronic databases RSCI, PubMed, MEDLINE, EMBASE Cochrane Central Register Controlled Trials (CENTRAL) were analyzed developers independently each other. date last search query was February 01, 2021. To...
Endotoxicosis is one of the main factors pathogenesis multiple organic dysfunctions in gram-negative sepsis, induced by accumulation lipopolysaccharides - wall components bacteria. In vitro removal them (LPS-adsorption) promotes better treatment outcomes sepsis patients. Development and introduction Russian tools for LPS-adsorption becomes more crucial. Objective: to evaluate efficiency safety column Toxipak endotoxin removal, manufactured POCARD Ltd. Materials methods: 7 adult patients who...
The article provides the main statements of guidelines for anesthesia and intensive care patients with coronavirus disease (COVID-19), developed by Federation Anesthesiologists Reanimatologists Russia. In process developing recommendations, publications official websites Russian Federation, electronic databases RSCI, PubMed, MEDLINE, EMBASE Cochrane Central Register Controlled Trials (CENTRAL) were analyzed developers independently each other. date last search query was June 29, 2020. To...
Project of the Russian National Atherosclerosis Society In 2016, Guidelines on medical care organization to patients with hereditary atherogenic lipid disorders in regions Russia were published, which described and presented principles routing dyslipidemia for them within current regulatory documents. December 2018, Ministry Health approved clinical guidelines diagnosis treatment familial hypercholesterolemia. Thus, persons a severe able get free medication expensive lipid-lowering drugs...
<h3></h3> Методы экстракорпоральной гемокоррекции широко используются в лечении сепсиса, системного воспалительного ответа и полиорганной недостаточности. Имеющийся спектр этих методов достаточно широк, вместе с тем продолжается их активное развитие совершенствование. Новая коронавирусная инфекция (COVID-19), проявляющаяся при тяжелых формах как сепсис или септический шок, характеризуется выраженным дисбалансом концентраций про- противовоспалительных медиаторов — цитокиновым штормом, который...
Rare diseases continue to present numerous challenges for the medical field worldwide. Understanding innovative mechanisms of service provision patients with rare conditions through shared communication across different healthcare systems should be encouraged. This study presents organization care people in Russia, while also exploring epidemiology both life-threatening and chronic, progressive, diseases. Further, regulation is examined, including preferential medicines Russian regions...
Family hypercholesterolemia is a monogenic autosomal dominant disease accompanied by significant increase of blood cholesterol, and as result, premature development progressive course atherosclerosis, usually at young age.Even in case the absence diseases caused atherosclerosis patients with family hypercholesterolmia belong to high-risk group very high risk cardiovascular complications if relevant.Aim.These practical recommendations are developed for physicians represent definition,...
One of the main causes mortality human immunodeficiency virus (HIV)-infected patients are complications chronic hepatitis C (HCV). Combining drug therapy for HCV with double filtration plasmapheresis (DFPP) has significantly increased effectiveness treatment these patients. However, there no data on use this method co-infected HIV and HCV. We demonstrated that positive clinical effect in by DFPP (previously demonstrated) is also achieved infected patients, The obtained efficiency 62.5%...
The objective : to provide pathogenetic justification for the need extracorporeal blood purification in new coronavirus infection. Results article analyzes guidelines and first experience of using methods infection different countries. It has been demonstrated that have complex pleiotropic (multiple) effects can quickly normalize level cytokines other pathogenic factors, thereby preventing/reducing severity organ disorders. specifies criteria choosing an method, as well indications its early...
Wilson-Konovalov disease is a severe progressive life-threatening hereditary autosomal recessive from the group of metabolic disorders with multisystem manifestations. Laboratory diagnostics basis for early diagnosis and timely initiation treatment, monitoring course disease, selecting evaluating effectiveness therapy, minimizing its side effects. Modern approaches to Wilson’s using laboratory research are presented in article. Examples phenotypic demonstrated. When tests used correctly, it...
Hypertriglyceridemia (HTG) is associated with an increased risk of atherosclerotic cardiovascular disease, pancreatitis developing, and all-cause mortality. The escalates rising triglyceride levels most significant in extreme HTG (triglycerides above 10 mmol/L). According to epidemiological studies the Russian Federation, prevalence varies between 0.1-0.2% (affecting 146,000 292,000 Russians). Extreme can be monogenic or polygenic (multifactorial), this determines clinical course disease....
The mortality of patients with hepatic failure remains high. Often the patient's life can be saved only extracorporeal liver support (ELS). ELS systems – MARS ® и Prometheus have proved their efficacy but widespread use is constrained by very high cost. Introduction in clinical practice new affordable a topical issue. objective: to compare and laboratory effects selective plasma exchange (SPE), plasmadialfiltration (PDF) membrane separators EvaclioTM (FPSA) treatment failure. Subjects...
The article describes ethical, social, psychological and medical problems in the families raising children with rare diseases. It is quite difficult to diagnose a disease. leads financial deprivation of family, social isolation marginalization. Patient organizations play large role public awareness crucial importance make treatment accessible, provide qualified care, support families, improve cooperation between research centers, institutions patients.
The results of the determination levels apoptosis in vitro lymphocytes during procedures extracorporeal photochemotherapy (extracorporeal photopheresis) using flow cytometry are described. It was found that carrying out photopheresis does not have a significant effect on viability cells immediately after procedures. Thus, relative content living samples isolation mononuclear fraction peripheral blood did differ from both prepared for and this procedure. should be noted lead to rapid cell...
Programmed immunoadsorption (IA) with regeneration of adsoption columns is a promising and safe technique to treat lupus nephritis (LN) in case ineffective immunosuppressive therapy its severe adverse reactions. This makes it possible control disease activity, maintain kidney function, ensure normal quality life. Due the reusability IA columns, remove any required amount IgG reduce cost an extracorporeal procedure. The paper describes clinical 3-year prolonged female patient systemic...