A5012671480- Healthcare Systems and Public Health
- Cardiovascular Disease and Adiposity
- Cardiovascular Function and Risk Factors
- Sepsis Diagnosis and Treatment
- Pneumonia and Respiratory Infections
- Diabetes Treatment and Management
- Hormonal Regulation and Hypertension
- Diet and metabolism studies
- Heart Rate Variability and Autonomic Control
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Long-Term Effects of COVID-19
- Hormonal and reproductive studies
- Cardiac Health and Mental Health
- Blood Pressure and Hypertension Studies
- Diet, Metabolism, and Disease
- Liver Disease Diagnosis and Treatment
- Lipoproteins and Cardiovascular Health
- Heart Failure Treatment and Management
- Pneumocystis jirovecii pneumonia detection and treatment
- Diabetes Management and Research
- Cancer, Lipids, and Metabolism
- Nutrition, Genetics, and Disease
- Regulation of Appetite and Obesity
- Restless Legs Syndrome Research
- Esophageal Cancer Research and Treatment
Novosibirsk State Medical University
2011-2025
Institute of Cytology and Genetics
2018-2025
Russian Academy of Sciences
2021-2025
Siberian Branch of the Russian Academy of Sciences
2019-2024
Research Institute of Therapy and Preventive Medicine
2019-2024
Russian Medical Academy of Continuous Professional Education
2023
Ministry of Health of the Russian Federation
2023
Tver State Medical University
2018
Aim. To assess awareness of blood pressure (BP) level, adherence to therapy and achievement target BP in residents Russian regions as part the 2023 hypertension (HTN) screening campaign. Material methods. During May 2023, 4613 participants from 23 cities Russia took screening. Participation was voluntary without restrictions on sex. All patients aged over 18 years. screening, pulse were measured three times using automatic or mechanical monitors, a questionnaire about behavioral risk...
Introduction. Porphyrias are a group of metabolic diseases caused by hereditary defects in the enzymatic system heme biosynthesis. According to modern classification porphyrias considered independent diseases, which specific defects, resulting certain disorders porphyrin metabolism and peculiarities clinical course disease. Acute intermittent porphyria (AIP) occupies special position hepatic its biochemical features unfavorable prognosis. Materials Methods. We present brief review literature...
Objective: To present a case of chronic diarrhea as an atypical manifestation primary adrenal insufficiency in young man. Main points: Diagnosis (AI) can take long time due to diverse and uncharacteristic initial symptoms. Diarrhea is not typical AI therefore be mistakenly considered infectious or irritable bowel syndrome even patients with established diagnosis AI. We (more than 6 months) man AI, which developed unsatisfactory therapy the underlying disease. After correction hypocorticism...
Background: One of the most controversial topics in scientific community urologists, cardiologists and endocrinologists is problem estrogen role male body. There are significant differences development evolution a number diseases, for example, cardiovascular, men women. In particular, mortality middle-aged young from diseases ardiovascular system significantly higher than women, which can be attributed to difference levels sex hormones - androgens estrogens. According world community,...
Familial hypercholesterolemia is an autosomal dominant disorder of lipid metabolism, leading to increase in plasma low-density lipoprotein cholesterol, followed by premature atherosclerosis. In women with familial hypercholesterolemia, pregnancy and lactation pose additional risk due the association physiological changes, pre-existing dyslipidemia, limited therapeutic options experience. A clinical case successful management a pregnant woman against background multifocal atherosclerosis...
Introduction . The most common extragenital pathology during pregnancy includes upper and lower respiratory tract infections (URTI LRTI), which, if left untreated, leading to obstetric perinatal pathology. It is relevant conduct pharmacoepidemiological studies assessing the preferences of specialists regarding treatment pregnant women attitudes towards vaccination in real clinical practice. Aim To analyze approaches pharmacotherapy URTI LRTI women, evaluate compliance prescribed drugs with...
Objective. To determine the level of knowledge doctors on rational use antimicrobial drugs in clinical practice and to compare with data previous stage study results obtained from students a parallel project. Materials Methods. A multicenter questionnaire survey practitioners analysis – KANT project (full name «Physicians’ (Students’) antimicrobials usage») conducted 2020–2023. Results. total 336 participants were surveyed 5 centers (10 Russian regions: Belgorod, Novosibirsk, Rostov,...
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Timely diagnosis of community-acquired pneumonia (CAP) and optimal timing initiation antibiotic therapy are important for reducing mortality in patients with HIV infection. It is reported that the assessment procalcitonin (PCT) levels this category can be a useful diagnostic tool. Aim. To determine new semi-quantitative rapid test (RT) PCT CAP depending on presence or absence Design. Cross-sectional comparative study. Material methods. The study involved 123 hospitalized CAP. 15 (12.2%)...
The problems of heart failure (HF) are becoming increasingly important every year due to the increasing spread cardiovascular diseases resulting in its development, as well impact metabolic factors, obesity, drugs and endocrine dysfunctions on myocardium. Isolation phenotypes with preserved, mid-ranged reduced ejection fraction HF allows ranking evidence base identifying groups patients preferred drug intervention strategies aimed at achieving six goals treating and, above all, reducing...
Aim: to describe post-COVID-19 cardiometabolic disorders in elderly patients and senile with comorbidities. Patients Methods: this cross-sectional comparative non-interventional study included 154 aged 60–89 years arterial hypertension (AH), ischemic heart disease (IHD), atrial fibrillation (AF) type 2 diabetes mellitus (DM2). The had similar frequency nosology of These were split into groups: the first group consisting 79 (66 [63; 73] old) who did not have novel coronavirus infection...
The current state of the Russian and foreign regulatory framework for off-label prescription medicines is presented in article. existing problems this specific drug therapy possible solutions are described. Unfortunately, there some gaps legislation regarding medication use. Based on clinical reality, cases, “off-label” drugs can be justified by condition patient, lack alternative approved drugs, availability published scientific data that create prerequisites effectiveness approach. When...
Introduction: The irrational use of medicines leads to a decrease in the quality care, an increase treatment costs and side effects. In case antibacterial drugs, addition all above-mentioned consequences, their improper can lead aggravation existing quite challenging problem our time – growth antibiotic resistance among pathogenic microorganisms.
 aim study: determine level basic knowledge medical specialists field rational antimicrobial drugs (AMD).
 Materials methods: study was...
Creation of a mathematical nonlinear regression model for prognostication 1 year outcomes after non-ST elevation acute coronary syndrome (NSTE ACS) optimization rehabilitation, secondary prevention, and personalized approach to treatment.We included in this study 135 patients with confirmed NSTE ACS (mean age 59.1±6.1 years, 94 men 41 women) admitted hospital No Novosibirsk during 2010. During hospitalization discharge these received standard medical therapy. All underwent clinical...
Glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 (GLP-1) are the incretin hormones initially discovered in 1960s. GIP GLP-1 have gained great scientific interest due to their properties increasing insulin secretion lowering blood glucose levels. The study of these has progressed substantially recent decades, that systemic effects begun be actively discussed. In particular, incretins involved pathogenesis obesity non-alcoholic fatty liver disease. Moreover, able...
Журнал для непрерывного медицинского образования врачей Новый полуколичественный экспресс-тест на прокальцитонин в диагностике внебольничной пневмонии зависимости от наличия нарушений углеводного обмена1 Научно-исследовательский институт терапии и
Научно-исследовательский институт терапии и профилактической медицины
Considering the increasing amount of elderly people in Russia and world, an active study arterial hypertension this group is actual clinically demanded task. The strategic direction defining treatment tactic such patients, especially over 80 years old, determination their functional status presence frailty syndrome, which not synonymous with comorbidity obligatory early aging companion, but specifies need for a personalized approach hypertension, even complete abolition antihypertensive...
Chronic heart failure (CHF) and type 2 diabetes mellitus (DM2) very common comorbidities with bidirectional, mutually aggravating courses. DM2 is known as an independent risk factor of cardiovascular complications whereas a higher CHF functional class associated increased DM2. At present time, hypoglycemic drugs the gliflozin angiotensin receptor-neprilysin inhibitor (ARNI) are widely discussed in connection their use treatment patients DM. The PARADIGM-HF study investigated effects...
Aim. Evaluation of the possibilities a new semi-quantitative rapid test for procalcitonin in diagnosis multisegmental community-acquired pneumonia. Materials and methods. A one-stage comparative study involved 123 patients hospitalized hospital with confirmed The mean age was 49.521.0 (MSD) years. On first day hospitalization, all underwent general clinical examination, chest x-ray, plasma level determined using test. Results. Indicators at least 2 ng/ml are directly related to laboratory...
Rhabdomyolysis is a very rare and most severe form of statin-induced muscle adverse event characterized by pain, necrosis with myoglobinemia and/or myoglobinuria high risk acute kidney injury death. The article presents case report developing rhabdomyolysis in middleaged female patient hypertension, decompensated type 2 diabetes albuminuria. A 60-year-old woman was admitted to the hospital for emergency indications complaints weakness that began neck, which spread over several days upper...
Introduction: The issues of rational antihypertensive therapy in pregnant women are always extremely relevant, since high blood pressure a woman is associated with serious risks for mother and fetus.
 aim the study: To determine knowledge preferences physicians management arterial hypertension.
 Materials methods: A multicenter study was conducted 2018–2021 using an anonymous questionnaire among 411 doctors from 8 regions Russia.
 Results discussion: levels specialists...