Е. А. Смирнова
A5033870663- Healthcare Systems and Public Health
- Heart Failure Treatment and Management
- Human Health and Disease
- Glaucoma and retinal disorders
- Blood Pressure and Hypertension Studies
- Erythropoietin and Anemia Treatment
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Cerebral Venous Sinus Thrombosis
- Acute Myocardial Infarction Research
- Neurological Disorders and Treatments
- Cardiac Health and Mental Health
- Cardiovascular Disease and Adiposity
- Retinal Diseases and Treatments
- Sodium Intake and Health
- Iron Metabolism and Disorders
- COVID-19 and healthcare impacts
- Potassium and Related Disorders
- Infective Endocarditis Diagnosis and Management
- Cardiac Arrhythmias and Treatments
- COVID-19 Clinical Research Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Systemic Lupus Erythematosus Research
- Venous Thromboembolism Diagnosis and Management
- Health Systems, Economic Evaluations, Quality of Life
Ryazan State Medical University named after Academician I.P. Pavlov
2016-2025
State Healthcare Institution "Regional Clinical Oncological Dispensary"
2021
Intersectoral Research and Technology Complex Eye Microsurgery
2021
Ryazan Institute of Management and Law
2021
Voronezh State Medical Academy named after N.N. Burdenko
2019
Cancer Research Center
2015
Academy of Medical Sciences
2015
Research Institute of General Pathology and Pathophysiology, the Russian Academy of Medical Sciences
2013
Aim To study the etiology and dynamics of prevalence mortality CHF; to evaluate treatment coverage such patients in a representative sample European part Russian Federation for 20-year period. Material methods A followed up 2002 through 2017 (n=19 276); population Nizhny Novgorod region examined 1998 (n=1922). Results During observation period since 2002, incidence major CHF symptoms (tachycardia, edema, shortness breath, weakness) tended decrease while cardiovascular diseases has...
Aim To study true prevalence of atrial fibrillation (AF) in a representative sample from the European part Russian Federation; to describe characteristics patients with AF; and provide frequency anticoagulant treatment.Material methods Cross-sectional data EPOCH epidemiological (2017) were used. Data collected 8 constituent entities size was 11 453 people. The included all respondents who had given their consent for participation older than 10 years. Statistical tests performed R system...
To perform a repeated epidemiological study of representative sample in the European part Russian Federation 2017 and to compare dynamics arterial hypertension (AH) prevalence with effectiveness blood pressure (BP) control population compared 1998, 2002, 2007.A was created 2002 re-examined 2007 2017. In pilot project performed for examining Nizhniy Novgorod region.During 19 years follow-up, AH increased from 35.5 43.3%. Te awareness treatment coverage reached 76.9 79.3%, respectively,...
Favorable versus detrimental cardiovascular responses to intermittent hypoxia conditioning (IHC) are heavily dependent on experimental or pathological conditions, including the duration, frequency and intensity of exposures. Recently, we demonstrated that a program moderate, normobaric IHC (FIO 2 9.5–10% for 5–10 min/cycle, with intervening 4 min normoxia, 5–8 cycles/day 20 days) in dogs afforded robust cardioprotection against infarction arrhythmias induced by coronary artery...
Aim. To assess awareness of blood pressure (BP) level, adherence to therapy and achievement target BP in residents Russian regions as part the 2023 hypertension (HTN) screening campaign. Material methods. During May 2023, 4613 participants from 23 cities Russia took screening. Participation was voluntary without restrictions on sex. All patients aged over 18 years. screening, pulse were measured three times using automatic or mechanical monitors, a questionnaire about behavioral risk...
Highlights Methods for modeling heart failure in rats are classified into models requiring surgical intervention, toxic, genetic and autoimmune models, based on the effects of physical factors, use special dietary regimens. It is impossible to single out a ideal model, since development multifactorial process, it preferable combination several methods. The correctness choice model its compliance with tasks future research must be confirmed by combining diagnostic methods verifying myocardial...
Aim To study the prevalence of senile frailty syndrome (FS), its impact on functional activity, quality life, management tactics, and prognosis in patients with acute decompensated heart failure (ADHF). Material methods The included 108 (58 men 50 women, mean age 69.2±10.7 years) admitted for ADHF. FS was diagnosed based presence clinical signs ADHF requiring intravenous therapy diuretics, vasodilators or inotropic drugs. Screening performed using "Age is Not a Hindrance" questionnaire....
Aim To evaluate the possibilities of screening for Fabry disease (FD) in a particular region Russian Federation. Material and methods This was an open prospective non-comparative study. The included patients with left ventricular (LV) hypertrophy >13 mm without severe hypertension; who had suffered stroke apparent cause; peripheral pain syndrome associated distal polyneuropathy predominant damage to small fibers; signs FD during physical examination; coarse facial features; angiokeratomas...
Aim. To assess the effectiveness of vaccination against Omicron and Delta variants according to international registry "Dynamics Analysis Comorbidities in SARS-CoV-2 Survivors" (AKTIV-4). Material methods. The AKTIV-4 included men women over 18 years age with a diagnosis coronavirus disease 2019 (COVID-19) (oropharyngeal nasopharyngeal swabs, antibody titers, typical computed tomography performance), undergoing hospital treatment. A total 3543 patients from 25 medical centers 7 countries...
Aim. To study real-world data on managing patients with coronary artery disease (CAD) and multifocal atherosclerosis (MFA) for 12 months by outpatient cardiologists. Material methods. KAMMA is a registry organized the Eurasian Association of Therapists. The main branch included men women over 18 years age confirmed in two or more arterial systems one risk factors atherosclerosis. start date patient recruitment was February 1, 2022 end November 27, 2022. design 3 following visits: 1 —...
Chronic heart failure with preserved ejection fraction (HFpEF) is a complex, heterogeneous, multi-organ systemic syndrome characterized by significant morbidity and mortality. Currently, it has acquired the character of an epidemic 21st century. The clinical observation describes typical story elderly patient suffering from coronary artery disease (CAD), dyslipidemia, atherosclerosis brachiocephalic arteries against background arterial hypertension (AH), obesity, type 2 diabetes mellitus...
The International Society of Hypertension and the World League initiated a blood pressure screening study called May Measurement Month 2019 (MMM19) to improve detection elevated (BP) assess BP control in patients with hypertension (HTN). Aim. To adherence treatment hypertensive population according MMM19 campaign Russia. Material methods. During 2019, 5394 people from 21 regions Russia took part screening. Participation was voluntary did not imply gender restrictions; all subjects were over...
Aim To evaluate the prevalence of iron deficiency (ID) in Russian patients with heart failure (HF).Material and methods Iron metabolism variables were studied 498 (198 women, 300 men) HF. Data evaluated at admission for HF (97 %) or during an outpatient visit (3 %). ID was determined according to European Society Cardiology Guidelines.Results 83.1 % had ID; only 43.5 anemia. Patients older: 70.0 [63.0;79.0] vs. 66.0 years [57.0;75.2] (p=0.009). The number increased parallel increase...
Aim. To analyze the lipid profile changes during acute phase of coronavirus disease 2019 (COVID-19) and within 12 months after discharge from hospital (post-Covid period) in comparison with patients before COVID-19. Material methods . The subanalysis registry was carried out as follows: clinical investigators each centers included AKTIV selected database who met three following criteria: (1) availability test no more than 60 days COVID-19; (2) period; (3) 6-12 hospital. Results In COVID-19,...
Aim . To investigate the prevalence and characteristics of polyvascular disease in Eurasian region's population with one or more previously established locations atherosclerotic arterial damage, to evaluate diagnostic importance ankle-brachial index (ABI) as a marker for (PVD). Material methods A total 1837 patients were included main branch KAMMA registry (patients PVD), among which 91,6% had coronary artery (CAD) (n=1683). For further analysis, group CAD was combined 1222 second —...
Aim . Comparative analysis of clinical, anamnestic, and laboratory instrumental data patients with chronic heart failure (CHF) iron deficiency (ID) diagnosed according to the AHA/ESC/RSC criteria, CHF ID based on decreased transferrin saturation (TSAT) ≤19.8% or serum (Fe) ≤13 μmol/l. Material methods An additional ID-CHF-RF study was performed. The analyzed population included 498 (198 women) CHF. In addition criteria provided by protocol (AHA/ESC/RSC criteria: ferritin <100 μg/l from...
Aim To analyze the main reasons for impairment of life prognosis patients with chronic heart failure (CHF) in real clinical practice Russian Federation. Material and methods Representative samples population Nizhny Novgorod region (1998, n=1,922) European part Russia followed from 2002 through 2017 (n=19,276), as well randomly selected medical records outpatients under dispensary monitoring CHF 19 therapeutic preventive institutions three constituent entities Federation (n=177, 2022) were...
INTRODUCTION: The problem of chronic heart failure (CHF) is relevant nowadays as never before. International experts estimate that more than 64.3 million people worldwide live with failure. In developed countries, its prevalence estimated at 1%–2% the total adult population; in our country, according to EPOCHA epidemiological study, it reaches 8.2%. AIM: To systematize current data on role myocardial fibrosis CHF and determine diagnostic significance laboratory markers. Myocardial being...
The relevance and importance of the problem acute decompensation heart failure (ADHF) for healthcare system worldwide is due to significant increase in number hospitalizations with associated material costs extremely unfavorable prognosis. article covers issues epidemiology, modern approaches diagnosis treatment ADHF. touches upon still unsolved differentiation between terms «acute failure» (AHF) chronic failure». Particular attention given risk factors causes ADHF, clinical phenotypes...
НАРУШЕНИЯ РИТМА СЕРДЦА У БЕРЕМЕННЫХ
Introduction Physical exercise (PE) is a necessary part in the treatment of patients with chronic heart failure (CHF), which stated European Society Cardiology guidelines and Russian Heart Failure guidelines. However, this type non-drug still not sufficiently used HF Russia. Aim To study current involvement PT to describe psychosocial factors that influence patients’ willingness potential barriers motivations for PE. Methods This was designed as an in-moment survey. Patients CHF who visited...
Repetitive quarantines and social restrictions during the coronavirus disease 2019 (COVID-19) pandemic have negatively affected population health in general, control of hypertension (HTN) particular. Aim . To evaluate HTN Russian COVID-19 period based on results screening for May Measurement Month 2021 (MMM2021). Material methods During May-August 2021, 2491 participants from 11 regions took part screening. Participation was voluntary without sex. All were over 18 years age. screening, blood...
Aim To evaluate the incidence of iron deficiency (ID) in men and women with chronic heart failure (CHF) to compare clinical functional indexes patient without ID depending on gender.Material methods An additional analysis study "Prevalence Iron Deficiency Patients With Chronic Heart Failure Russian Federation (ID-CHF-RF)" was performed. The included 498 (198 women, 300 men) patients CHF, whom, addition metabolism, quality life exercise tolerance (ET) were studied. 97 % enrolled during their...
Aim . To study the nine-year dynamics of prevalence, risk factors, approaches to treatment arterial hypertension (AH) in Ryazan region according a representative sample survey, assess impact factors and cardiovascular diseases on achieving blood pressure (BP) control. Material methods A population region, created 2002 by method step-by-step randomization, was reexamined 2007 2016. The group AH included people with >140/90 mm Hg. double measurement or normal pressure, receiving...