Е. В. Макарова
- Long-Term Effects of COVID-19
- Healthcare Systems and Public Health
- COVID-19 Clinical Research Studies
- Human Health and Disease
- COVID-19 and healthcare impacts
- Cardiovascular Health and Disease Prevention
- Chronic Obstructive Pulmonary Disease (COPD) Research
- SARS-CoV-2 and COVID-19 Research
- Inhalation and Respiratory Drug Delivery
- Antiplatelet Therapy and Cardiovascular Diseases
- Pediatric health and respiratory diseases
- Cardiovascular Disease and Adiposity
- Respiratory and Cough-Related Research
- Respiratory Support and Mechanisms
- Noise Effects and Management
- Cardiac Imaging and Diagnostics
- Medical Imaging Techniques and Applications
- Asthma and respiratory diseases
- Climate Change and Health Impacts
- Liver Disease Diagnosis and Treatment
- Thermoregulation and physiological responses
- Neurological Disorders and Treatments
- Blood Pressure and Hypertension Studies
- Technology and Human Factors in Education and Health
- Radiopharmaceutical Chemistry and Applications
Privolzhsky Research Medical University
2015-2025
City Clinical Hospital
2021-2025
Nizhny Novgorod Research Institute of Traumatology and Orthopedics
2021-2023
Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
2021-2023
Central Scientific Research Institute of Traumatology and Orthopedics
2022
N. I. Lobachevsky State University of Nizhny Novgorod
2015
Moscow Architectural Institute
2011
Academy of Medical Sciences
2009
Russian Academy of Sciences
1994-2009
Essen University Hospital
1998
Aim. To study the clinical course specifics of coronavirus disease 2019 (COVID-19) and comorbid conditions in COVID-19 survivors 3, 6, 12 months after recovery Eurasian region according to AKTIV register. Material methods. The register was created at initiative Association Therapists. is divided into 2 parts: 1 2. currently includes 6300 patients, while — 2770. Patients diagnosed with receiving in- outpatient treatment have been anonymously included on registry. following 7 countries...
The international AKTIV register presents a detailed description of out- and inpatients with COVID-19 in the Eurasian region. It was found that hospitalized patients had more comorbidities. In addition, these were older there men than among outpatients. Among traditional risk factors, obesity hypertension significant negative effect on prognosis, which for 60 years age older. comorbidities, CVDs maximum this other type 2 1 diabetes, chronic kidney disease, obstructive pulmonary cancer anemia...
The organizer of the registers “Dynamics analysis comorbidities in SARSCoV-2 survivors” (AKTIV) and “Analysis hospitalizations comorbid patients infected during second wave SARS-CoV-2 outbreak” (AKTIV 2) is Eurasian Association Therapists (EAT). Currently, there are no clinical registries region designed to collect analyze information on long-term outcomes COVID-19 survivors with conditions. aim register assess impact a novel coronavirus infection course chronic non-communicable diseases 3,...
ACTUALITY. Geriatric syndromes affect the course of chronic diseases. One confirmations this is frequent detection sarcopenia in elderly people suffering from type 2nd diabetes. This directly related to progression polyneuropathy, as there a decrease muscle strength lower extremities. In paper, we studied relationship between development with presence and diabetic polyneuropathy older patients. Early geriatric patients leads multifactorial disease control, which increases duration quality life
Aim. To assess the effectiveness of vaccination against Omicron and Delta variants according to international registry "Dynamics Analysis Comorbidities in SARS-CoV-2 Survivors" (AKTIV-4). Material methods. The AKTIV-4 included men women over 18 years age with a diagnosis coronavirus disease 2019 (COVID-19) (oropharyngeal nasopharyngeal swabs, antibody titers, typical computed tomography performance), undergoing hospital treatment. A total 3543 patients from 25 medical centers 7 countries...
Aim. Study the impact of various combinations comorbid original diseases in patients infected with COVID-19 later on disease progression and outcomes new coronavirus infection. Materials methods. The ACTIV registry was created Eurasian Association Therapists initiative. 5,808 have been included registry: men women treated at hospital or home. ClinicalTrials.gov ID NCT04492384. Results. Most (oCDs). Polymorbidity assessed by way simple counting oCDs is an independent factor negative COVID-19....
Aim To study the effect of regular drug therapy for cardiovascular and other diseases preceding COVID-19 infection on severity outcome based data ACTIVE (Analysis dynamics Comorbidities in paTIents who surVived SARS-CoV-2 infEction) registry.Material methods The registry was created at initiative Eurasian Association Therapists. includes 5 808 male female patients diagnosed with treated a hospital or home due protection patients' privacy (data nasal throat smears; antibody titer; typical CT...
Aim . To analyze newly diagnosed diseases and features of the post-COVID course in patients after a coronavirus disease 2019 (COVID-19) within 12-month follow-up. Material methods A total 9364 consecutively hospitalized were included ACTIV registry. Enrollment began on June 29, 2020, was completed March 30, 2021, corresponding to first second waves pandemic. Demographic, clinical, laboratory data, computed tomography (CT) results, information about inhospital clinical complications COVID-19...
COVID-19 is a severe infection with high mortality. The concept of the disease has been shaped to greater extent on basis large registers from USA, Spain, Italy, and China. However, there no information characteristics in Caucasian patients.Therefore, we created an international register estimated capacity 5,000 patients — Dynamics Analysis Comorbidities SARS-CoV-2 Survivors (AKTIV SARS-CoV-2), which brought together professionals Russian Federation, Republic Armenia, Kazakhstan, Kyrgyz...
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Aim . To investigate on post-COVID period in patients of the Eurasian region. Material and methods A total 9364 consecutively hospitalized were included ACTIV registry. Enrollment began June 29, 2020, was completed March 30, 2021, corresponding to first second waves pandemic. Demographic, clinical, laboratory data, computed tomography (CT) results, information about inhospital clinical course complications COVID-19 during hospitalization extracted from electronic health records using a...
BACKGROUND. There is enough evidence of the negative impact excess weight on formation and progression res piratory pathology. Given continuing SARS-CoV-2 pandemic, it relevant to determine relationship between body mass index (BMI) clinical features novel coronavirus infection (NCI). AIM. To study effect BMI course acute SARS-COV-2 post-covid period. MATERIALS AND METHODS. AKTIV 2 are multicenter non-interventional real-world registers. The АКТИВ registry (n=6396) includes non-overlapping...
Chronic cough declines quality of life and increases risk complications in patients with chronic obstructive pulmonary disease (COPD). Reducing severity associated negative effects is important therapeutic goal COPD. Rengalin anti- protussive activity based on technologically processed antibodies to bradykinin, histamine morphine.To evaluate efficacy safety treatment COPD.Patients (n=238, mean age 64.3±8.2 years) stable COPD persistent despite maintenance therapy (anticholinergics,...
To investigate the efficacy and safety of nebulized budesonide systemic glucocorticosteroids (GCS) (SGCS) in treatment an exacerbation chronic obstructive pulmonary disease (COPD) their effects on serum concentration soluble leukocyte differentiation antigens.Seventy-eight hospitalized patients with acute COPD were randomized into two groups: 1) 37 took 4 mg/day; 2) 41 received intravenous prednisolone. The symptoms COPD, forced expiratory volume one second (FEV1) other spirometric...
The aim of the investigation was to assess possibilities modern methods for oxidative stress and immune profile research in determining predictors chronic inflammatory process young smokers bronchi.Materials Methods.85 students I-III-year from Nizhny Novgorod State Medical Academy were examined, among them 30 (group 1) non-smokers 55 2) addicted nicotine.The pulmonary function test, oxidant-antioxidant system, levels soluble differentiating molecules leucocytes histocompatibility studied...
The objective of the study was to investigate prevalence smoking and its influence on parameters arterial stiff ness in men working age. Material methods . included 86 aged 37.6 ± 7.6. intensity assessed. Among experimental subjects, 48 people were selected divided into two groups (smokers non-smokers) comparable due other cardiovascular risk factors. In both groups, rigidity studied by volumetric sphygmography. Results discussion tobacco 46.5%, half smokers had a index greater than 10...
Introduction. In this study, we aimed to identify the features of dynamics cardiovascular diseases (CVD) and risk factors for its development in individuals who have worked under influence noise a long time. Patients Methods. 56 archival case histories patients with occupational sensorineural hearing loss 47 outpatient records relative silence were studied. CVD analyzed dynamics. Results. The groups comparable age, body mass index, prevalence smoking, obesity burdened heredity. loss, total...
Aim. To present data from the AURA Registry (real-world registry on AlbUminuRia detection rate among patients with previously undiAgnosed chronic kidney disease). It is important to perform population studies both study occurrence of markers (albuminuria (AU), decreased glomerular filtration (GFR)) and prevalence disease (CKD), which will provide information actual CKD related in territories included research centers. Material methods . The article presents first registry. Recruitment was...
Aim . To study the lipid profile in hospitalized patients with coronavirus disease 2019 (COVID-19) depending on outcome of its acute phase according to AKTIV international registry. Material and methods The registry included men women over 18 years age a diagnosis COVID-19, who were treated hospital. A total 9364 registry, which 623 analyzed for levels cholesterol, low-density lipoprotein cholesterol (LDL-C) triglycerides days 1-2 hospitalization. level high-density (HDL-C) was calculated...