A5045302326- Healthcare Systems and Public Health
- Human Health and Disease
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Effects of Exercise
- Cardiomyopathy and Myosin Studies
- Cardiac Arrhythmias and Treatments
- Neurological Disorders and Treatments
- Medical and Biological Sciences
- Atrial Fibrillation Management and Outcomes
- Nutrition, Genetics, and Disease
- Enhanced Oil Recovery Techniques
- Biomarkers in Disease Mechanisms
- Reservoir Engineering and Simulation Methods
- S100 Proteins and Annexins
- Cardiac Imaging and Diagnostics
- Cardiac pacing and defibrillation studies
- Acute Myocardial Infarction Research
- Educational Innovations and Challenges
- Sinusitis and nasal conditions
- Pediatric health and respiratory diseases
- Receptor Mechanisms and Signaling
- COVID-19 and Mental Health
- Cytokine Signaling Pathways and Interactions
- Cardiovascular and Diving-Related Complications
- Venous Thromboembolism Diagnosis and Management
Krasnoyarsk State Medical University
2016-2025
Federal Medical-Biological Agency
2025
Oxfam
2023-2024
Lomonosov Moscow State University
2016-2023
Moscow State University
2016-2023
Innsbruck Medical University
2021-2022
Southern Federal University
2021
City Clinical Hospital No. 2
2018-2020
National Research Mordovia State University
2020
Krasnoyarsk Regional Clinical Hospital
2019
Background: COVID-19-related mental health problems are considered a public challenge. The aim of this study was to investigate psychological distress, loneliness, and boredom among the general population federal state Tyrol, Austria. Methods: Residents Tyrol aged ≥ 18 years were recruited via dissemination link through social media other advertisements invited complete an online survey from June 26th August 20th, 2020. Next collection sociodemographic COVID-19 related variables Brief...
Background: During the first 3 weeks of COVID-19 pandemic, federal state Tyrol, Austria had one strictest curfews in and worldwide. The aim current study was to investigate assumingly protective role resilience extraversion its impact on mental health following such an uncertain unpredictable situation. Methods: Between second wave adult residents Tyrol were invited participate online survey. Next assessment sociodemographic COVID-19-related variables Brief-Symptom-Checklist, Three-Item...
Research on the long-term mental health impact of COVID-19 pandemic across disorders is limited, and information public policy measures with varying strictness missing. This study therefore aimed at investigating psychological distress among residents Tyrol (Austria) South (Italy) early stages 5 months thereafter examined how sociodemographic, protective, risk factors relate to change over time. One hundred fifteen people severe illness (SMI; schizophrenia spectrum disorder, bipolar major...
The Expert Council was devoted to the development of algorithm diagnostics and treatment anxiety disturbances in patients with somatic diseases general clinical practice. level clinicians from various medical fields took part creation algorithm, which allowed take into account different approaches opinions. is aimed at identifying a profile their timely treatment. Temgicoluril discussed as one recommended drugs for conditions outpatient
Hypertension is one of the most common diseases, especially among pregnant women. The combination hypertension and obesity a serious problem that requires careful medical monitoring. This literature review highlights impact in women association with on risks gestational period adverse pregnancy outcomes, within framework research works by Russian foreign authors. search for publications English was carried out databases electronic resources PubMed (MEDLIN), Scopus, eLIBRARY using following...
The International Society of Hypertension and the World League initiated a blood pressure screening study called May Measurement Month 2019 (MMM19) to improve detection elevated (BP) assess BP control in patients with hypertension (HTN). Aim. To adherence treatment hypertensive population according MMM19 campaign Russia. Material methods. During 2019, 5394 people from 21 regions Russia took part screening. Participation was voluntary did not imply gender restrictions; all subjects were over...
Next to an increased use of alcohol, the current pandemic has been associated with psychological distress among general population. Research on its effects individuals suffering from substance disorders (SUD) is scarce. This study aimed at expanding existing literature this topic a focus impact loneliness and perceived social support.Sixty-eight people diagnosed SUD according ICD-10 Austrian state Tyrol Italian Province South who had treated in psychiatric hospital 2019 one hundred...
Abstract. We present a method for accelerated optimisation of CO2 injection into petroleum reservoirs. The assumes maximisation the net value by coupling reservoir models with calculation cash flows. proposed is based on construction hierarchy compositional increasing complexity. show that in dimensionless volumes, optimal water and gas slugs are very close 1-D 2-D areal water-alternating-gas (WAG) process. Therefore, solution to problem gives good approximation problem. designed using this...
The aim of this study was to investigate the predictive value rs1805124 polymorphism SCN5A gene with regard idiopathic cardiac conduction disorders.The AG genotype frequency significantly higher in patients an atrioventricular block (61,2%±6,0%) compared healthy control subjects (34,8%±2,3%), p<0.0001. frequencies among only complete right bundle-branch (CRBBB) (54,2%±5,5%) and those both CLBBB LAH (50%±5,1) were than group p<0.005.The H558R (rs1805124) is a genetic predictor disorders...
Aim. To study the prevalence of elevated concentrations lipoprotein (a) (Lp(a)) and apolipoprotein B (apoB) associated with high cardiovascular risk in a random sample adult Krasnoyarsk population. Material methods. Lp(a) apoB were determined by immunochemiluminescent method using an automated modular Cobas 8000 platform biochemical module c702 (Roche Diagnostic, Switzerland). We examined 263 people aged 18 to 58 who agreed expand standard screening determination. Results. found that very...
The purpose of this study was to establish the probability and patterns atrial fibrillation (AF) inheritance in families, find an association primary secondary AF with polymorphism Ser49Gly gene encoding beta1-adrenoreceptor (ADRB1).We examined 103 probands 301 relatives. Physical examination, electrocardiography (ECG), echocardiography, Holter's monitoring ECG, other methods functional diagnostics have been performed for all patients their Genetic has using DNA extracted from peripheral...
Background . The International Society of Hypertension and World Hypertensive League therefore joined forces to organize a concerted global effort by expanding Day May Measurement Month 2017 (MMM17). campaign was aimed improve hypertension awareness blood pressure control in participants with hypertension. Russian Cardiology supported initiative — measurement performed 11 cities. Objective aim our study estimate population about terms MMM17. Design methods During we screened 1532 cities: St...
Background:Amitochondrialspecificdeacetylase,Sirtuin-3hasbeenreportedtoregulateoxidative phosphorylation, the activity of Cyclophilin D (a key component mitochondrial permeability transition pore, MPTP), and ROS scavenger MnSOD. We hypothesised that Sirtuin-3 could be a potential therapeutic target for cardio-protection based its ability to prevent MPTP formation inhibit generation. MethodsandResults:InHL-1cells(amurinecardiaccellline),over-expressionofSirtuin-3reduced cell death following...
Abstract Since the establishment of anthracycline drugs cardiotoxigenic effect, most widely accepted mechanistic base for their iatrogenic cardiotoxicity was connected with excessive and inadequate intensification LPO. However, ineffectiveness antioxidant multivitamin regimens cardio-protection caused necessity finding new pathogenic targets, exposure to which will prevent development cardiovascular symptoms. Such a target became nuclear topoisomerases, study results served as foundation...
Background: The Covid-19 pandemic and related measures represent an enormous burden on mental health. aim of this study was to investigate longitudinal changes in psychological distress, loneliness, boredom, resilience over the course examine associations between extraversion at baseline (summer 2020) boredom 5-month-follow-up. Methods: Residents Tyrol (≥18a) completed online survey resilience, by using Brief-Symptom-Checklist, Three-Item Loneliness Scale, Multidimensional State Boredom...
Atrial fibrillation (AF) is the most common heart rhythm disturbance. It believed that primary form of AF genetically determined in cases, but genetic component cannot be excluded secondary AF. a heterogeneous disease and many authors proved its relationship with other disease. In certain combinations polymorphisms different genes promote development The study renin-angiotensin-aldosterone system (RAAS) especially important, because role this pathogenesis currently studding intensively....
Repetitive quarantines and social restrictions during the coronavirus disease 2019 (COVID-19) pandemic have negatively affected population health in general, control of hypertension (HTN) particular. Aim . To evaluate HTN Russian COVID-19 period based on results screening for May Measurement Month 2021 (MMM2021). Material methods During May-August 2021, 2491 participants from 11 regions took part screening. Participation was voluntary without sex. All were over 18 years age. screening, blood...
Aim. To study of the relationship between gene polymorphisms ( FGA , ITGA2 PAI1 ) and pulmonary embolism (PE). Material methods. We examined 120 patients with embolism, who made up main group (mean age, 63,22±3,16 years). There were 66 men 60,24±3,17 years) 54 women 6,19±3,67 The control consisted 200 people 64,92±3,50 DNA Bank Research Institute Internal Preventive Medicine was formed during a series population screenings. All signed written informed consent to participate in molecular...
Aim . To study the relationship of rs1800470 polymorphic variants transforming growth factor p1 (TGF-β1) gene with severity coronary arteries (CA) atherosclerosis. Material and methods The included 256 patients myocardial infarction (MI) (216 males 40 females) a Caucasoid race aged <65 years (52,1 ±8,4). Phenol-chloroform extraction was used for separating DNA from venous blood. polymorphism TGF-β1gene tested using real-time polymerase chain reaction (PCR) (TaqMan probes, AB 7900HT)....
Objective Familial atrial fibrillation (FAF), a not uncommon arrhythmia of the atrium, is characterized by heritability, early onset and absence other heart defects. The molecular genetic basis still completely clear diagnosis cannot be achieved in about 90% patients. In this study, we present results screening next generation sequencing affected Russian families. Patients methods Sixty subjects (18 probands 42 relatives) with clinical FAF were enrolled study. Since AF frequently associates...
We studied the role of endothelial nitric oxide synthase gene polymorphism 4a/4b in development such disturbances cardiac conduction as atrioventricular (AV) block and sick sinus node syndrome (SSNS). examined 69 subjects (36 men, 33 women) with AV 90 (33 men 57 SSNS. They were divided into groups dependence on type disorder sex. Probands pathologies composed separate groups. All participants underwent included clinical-instrumental cardiological examination molecular genetic study eNOS...