A5081090588- Healthcare Systems and Public Health
- Frailty in Older Adults
- Heart Failure Treatment and Management
- Heart Rate Variability and Autonomic Control
- Cardiovascular Health and Disease Prevention
- Blood Pressure and Hypertension Studies
- Cardiovascular Syncope and Autonomic Disorders
- Intensive Care Unit Cognitive Disorders
- Cardiovascular Function and Risk Factors
- Cardiac Health and Mental Health
- Cardiac, Anesthesia and Surgical Outcomes
- Long-Term Effects of COVID-19
- Genetics, Aging, and Longevity in Model Organisms
- Human Health and Disease
- Telomeres, Telomerase, and Senescence
- Neurological Disorders and Treatments
- Erythropoietin and Anemia Treatment
- Cardiac Imaging and Diagnostics
- Nutrition and Health in Aging
- Cardiovascular Health and Risk Factors
- Hip and Femur Fractures
- Cardiovascular and exercise physiology
- COVID-19 Clinical Research Studies
- Iron Metabolism and Disorders
- Circadian rhythm and melatonin
Pirogov Russian National Research Medical University
2019-2025
Institute for Regional Economics
2024
Ministry of Health of the Russian Federation
2020-2024
Moscow Power Engineering Institute
2022-2023
National Medical and Surgical Center named after N.I. Pirogov
2022
Russian Scientific Center of Surgery
2021
British Heart Foundation
2018
King's College London
2018
While eHealth can help improve outcomes for older patients receiving geriatric rehabilitation, the implementation and integration of is often complex time-consuming. To use effectively in it essential to understand experiences needs healthcare professionals. In this international multicentre cross-sectional study, we used a web-based survey explore use, benefits, feasibility usability rehabilitation settings, together with working Descriptive statistics were summarize quantitative findings....
Background . The trend towards aging of the population is global, which makes study etiology, prevention and treatment age-related disorders relevant. Increasing number studies highlights influence 25-hydroxyvitamin D deficiency on health state in older people, as well its correlation with geriatric syndromes prevalence. However, at moment it not known whether these patterns persist patients than 90 due to limited this population. Aim To assess prevalence vitamin a cohort centenarians...
Ischemic heart disease, including previous myocardial infarction (MI), is one of the main causes for development and progression failure (HF). The presence HF before MI or in setting acute coronary catastrophe an extremely unfavorable prognostic factor leading to a multiple increase risk death rehospitalization due post-infarction period. In 2024, results two randomized clinical trials (RCTs) (DAPA-MI EMPACT-MI) were published, which assessed effect sodium-glucose co-transporter type 2...
BACKGROUND. The number of patients with Chronic Heart Failure (CHF) worldwide is increasing. prevalence CHF increases age: more than 10 % among people over 70 years age, and up to in 90 age. As individuals the incidence geriatric syndromes also increases. Despite this, large randomized clinical trials on have low representation older age groups frailty.
BACKGROUND. Currently, the number of patients with chronic heart failure (HF) is increasing worldwide [1]. Most them are elderly [2]. The progression HF affects quality life and can lead to dependence on outside help. it relevant assess functional status in HF.
RELEVANCE. Cardiovascular diseases (CVD) remain the leading cause of death worldwide. Predicting future occurrence CVD remains a serious problem in medicine. In recent decades, progressive and exponential population aging has led to an increase prevalence frailty syndrome (FS) other geriatric syndromes (GS), one which is orthostatic hypotension (OH). Frailty OHsignificantly reduce quality life older people. The relationships between them unclear. With vascular wall aging, arterial elasticity...
Objective — the main objective of study is to test hypothesis that achieving lower recommended target levels (LRT) blood pressure (BP) in elderly and senile patients with arterial hypertension (HTN) will be no less safe than higher (HRT) BP HTN, which assessed using home measurement data a remote monitoring system for effectiveness safety antihypertensive therapy. Design methods. The expected include 60 aged 65 years older, who randomly assigned LRT or HRT group achievement SBP (according...
A comprehensive geriatric assessment is the main diagnostic tool in work of a geriatrician, which also necessary for drawing up an individual plan managing older patient. distinctive feature approach holistic perception all needs person — not only medical, but functional, social. The goals CGA (comprehensive assessment) are to improve diagnostics, optimize treatment, and enhance functional state quality life, including living conditions, use health-care services, planning long-term support...
Background Assessing the physiological significance of stenoses with coexistent serial disease is prone to error. We aimed use 3-dimensional-printing characterize stenosis interplay and derive validate a mathematical solution predict true in disease. Methods Results Fifty-two 3-dimensional-printed phantoms were physiologically assessed by pressure-wire pullback (Δ FFR
In recent years, Russia has seen an increase in the proportion of older patients receiving surgical care. majority cases, patient is burdened with multiple long-term conditions (MLTC) and geriatric syndromes. To improve consensus clinical / or functional outcomes after surgery, rehabilitation measures are required postoperative period. this review, spanning last 10 value programs for oldest-old was assessed. The effectiveness multidisciplinary period analyzed.
In this article, the authors discuss principles of perioperative management patients in older age group with frailty syndrome. Most syndrome have several chronic diseases; associations cardiovascular diseases are known — arterial hypertension, coronary heart disease, failure, as well diabetes mellitus, kidney joints and lower respiratory tract, oncological diseases, which causes a higher risk complications postoperative period requires special approach period. This protocol addresses issues...
The demographic shift towards an increasing number of older and oldest-old individuals is a global phenomenon. This trend has been accompanied by rise in surgical interventions targeting aged 65 years above. However, the traditional clinical approach to treating single diseases often proves insufficient for geriatric patients due multiple factors, such as presence chronic conditions, use medications, physical frailty, malnutrition, cognitive impairments, diminished physiological function....
Introduction Growing evidence supports ischemia-guided management of chest pain, with invasive and non-invasive tests reliant upon achieving adenosine-induced coronary hyperemia (defined as increased blood flow to an organ's perfusion bed). In the setting, surrogate markers hyperemia, such increases in heart rate, are often used, despite not being formally validated. We tested whether rate other indices reliable hyperemia. Methods The first part involved Doppler flow-based validation best...
Aim To evaluate the prevalence of iron deficiency (ID) in Russian patients with heart failure (HF).Material and methods Iron metabolism variables were studied 498 (198 women, 300 men) HF. Data evaluated at admission for HF (97 %) or during an outpatient visit (3 %). ID was determined according to European Society Cardiology Guidelines.Results 83.1 % had ID; only 43.5 anemia. Patients older: 70.0 [63.0;79.0] vs. 66.0 years [57.0;75.2] (p=0.009). The number increased parallel increase...
Senile asthenia syndrome (SAS) is a geriatric characterized by age-associated decline of the physiological reserve and function in multiple systems, which results higher vulnerability to effects endo- exogenous factors high risk unfavorable outcomes, loss self-sufficiency, death. Generally, SAS observed elderly patients with comorbidities. In cardiovascular diseases, associated poor prognosis, including incidence exacerbation death both during acute events chronic disease. However, often not...
The prevalence of chronic kidney disease (CKD) increases with age, but CKD is often underdiagnosed in older adults and regarded as age-related changes function. Screening for mandatory should include estimated glomerular filtration rate (eGFR) using both the EPI creatinine-based formula albumin/creatinine ratio a urine spot sample. In diagnostic criteria are same younger subjects. associated advanced ageing requires careful assessment geriatric syndromes. Renal function be assessed at least...
Aim . Comparative analysis of clinical, anamnestic, and laboratory instrumental data patients with chronic heart failure (CHF) iron deficiency (ID) diagnosed according to the AHA/ESC/RSC criteria, CHF ID based on decreased transferrin saturation (TSAT) ≤19.8% or serum (Fe) ≤13 μmol/l. Material methods An additional ID-CHF-RF study was performed. The analyzed population included 498 (198 women) CHF. In addition criteria provided by protocol (AHA/ESC/RSC criteria: ferritin <100 μg/l from...
A fall is defined as an event, which results in a person coming to rest inadvertently on the ground or floor other lower level, except cases, are result of blow, loss consciousness, sudden paralysis epilepsy [1]. Falls and fear falling cause serious health problems, which, turn associated with high injury rate, medical costs negative impact quality life. Older senile patients cardiovascular disease (CVD) at risk falling. However, clinical practice, prevalence falls risks not well understood...
Cardiovascular diseases are the main death causes in modern world. Heart failure (HF) is terminal stage of most cardiovascular diseases. The prevalence HF increasing patients older age groups. At same time, number geriatric syndromes increases with age, one which malnutrition. Recent studies demonstrate mutually aggravating effect heart and malnutrition, that correction malnutrition can improve course. introduction screening timely will reduce hospitalization mortality rates HF.
The prevalence of older people in Russian population increases rapidly. Therefore, the concept healthy aging is becoming crucial Russia and all over world, thus disability prevention one aspect this issue. Aim To assess a possible association between geriatric syndromes, comorbidities, mortality rate among frail patients who receive home medical care Moscow. Materials methods study included 450 with provided by State Budgetary Healthcare Institution “Diagnostic Center No. 3 Moscow Health...
Aim To evaluate the incidence of iron deficiency (ID) in men and women with chronic heart failure (CHF) to compare clinical functional indexes patient without ID depending on gender.Material methods An additional analysis study "Prevalence Iron Deficiency Patients With Chronic Heart Failure Russian Federation (ID-CHF-RF)" was performed. The included 498 (198 women, 300 men) patients CHF, whom, addition metabolism, quality life exercise tolerance (ET) were studied. 97 % enrolled during their...
The review includes data over the past 20 years on mechanisms of influence hypertension and related interdependent conditions, such as insulin resistance, chronic inflammation oxidative stress vascular ageing. also discusses modern concepts interaction biological aging, well possible ways their reversal. central indicators aging in this are telomere length telomerase activity. article antihypertensive therapy a way to slow down both describes results studies effect various antihypertensives,...
Aim: to assess the most important metabolic factors in centenarians and their impact on prognosis Materials methods. It was a longitudinal study, including 64 (95 years older), who live Moscow. Complex geriatric assessment (FRAIL, IADL-C, MNA, GDS-15 МOCA scores) blood tests (HbA1c, cholesterol, LDL, HDL TG) were performed. In 3 we contacted patients’ relatives or social workers find out about status. Results. Mean age of patients 98,3±1,9 years. We found that 34,4% frail. Cognitive...