- Stress Responses and Cortisol
- Antimicrobial agents and applications
- Probiotics and Fermented Foods
- Bacterial biofilms and quorum sensing
- Essential Oils and Antimicrobial Activity
- Immune Response and Inflammation
- Antimicrobial Resistance in Staphylococcus
- Immune Cell Function and Interaction
- Antibiotics Pharmacokinetics and Efficacy
- Pharmaceutical and Antibiotic Environmental Impacts
- Neuroendocrine regulation and behavior
- Antibiotic Resistance in Bacteria
- Neuroscience and Neuropharmacology Research
- Bacterial Identification and Susceptibility Testing
- Phytochemicals and Antioxidant Activities
- Fatty Acid Research and Health
- Pneumocystis jirovecii pneumonia detection and treatment
- Clostridium difficile and Clostridium perfringens research
- Hormonal and reproductive studies
- Tryptophan and brain disorders
- Birth, Development, and Health
- Antibiotic Use and Resistance
- Salmonella and Campylobacter epidemiology
- Antifungal resistance and susceptibility
- Viral gastroenteritis research and epidemiology
Universidad de Jaén
2015-2025
Henry M. Jackson Foundation
2025
Tulane University
2025
Universidad de Granada
2001-2023
Numerous studies have previously demonstrated the antimicrobial activity of plant extracts rich in procyanidins. However, these investigations that focused on uncharacterized do not provide information structure-activity relationships compounds. The aim this work was to investigate antibacterial and antibiofilm properties 27 phenolics with coumarin, naphthoquinone pyranone moieties against foodborne microorganisms, as well establish relationships. Minimal inhibitory concentrations (MICs) for...
The enzyme 5alpha-reductase (5alpha-R) is present in many mammalian tissues, including the brain. physiological importance of 5alpha-R brain derives from its capability to convert testosterone (T) a more potent androgen, dihydrotestosterone (DHT), and progesterone deoxycorticosterone (DOC) their respective 5alpha-reduced derivatives, precursors allopregnanolone tetrahydroDOC, allosteric modulators gamma-aminobutyric acid receptor (GABA(A)-R). occurs as two isoforms, type 1 (5alpha-R1) 2...
Natural A-type procyanidins have shown very interesting biological activities, such as their proven antiadherence properties against pathogenic bacteria. In order to find the structural features responsible for we describe herein design and synthesis of six procyanidin analogues evaluation antimicrobial antibiofilm 12 resistant bacteria, both Gram positive negative, isolated from organic foods. The natural A-2, which had known activity, was also tested a reference compound comparative...
Summary This study aimed to evaluate the antimicrobial and antibiofilm activities of two procyanidins isolated from an ethyl acetate extract laurel wood against a selection foodborne pathogens. The analysis by HPLC – DAD / ESI MS allowed us detect presence procyanidins, which were selectively identified chromatographic spectroscopic means as cinnamtannin B‐1 ( 1 ) procyanidin B‐2 2 ). Procyanidins exhibited biological activities: inhibition bacterial growth at high concentrations prevention...
Chlorhexidine (CH) and quaternary ammonium compounds (QAC), such as cetrimide (CE), are widely used disinfectants because of their broad antimicrobial spectrum. However, frequent use for disinfection in different settings may promote bacterial drug resistance against both biocides clinically relevant antibiotics. This study analyzes the effects stepwise exposure to (CE) chlorhexidine bacteria from organic foods previously classified biocide-sensitive. Gradual these strains resulted mainly...
Abstract BACKGROUND Heavy metal pollution may act as persistent selective pressure that favors the spread of antimicrobial resistance in natural environments. The aim this study was to isolate and identify metal‐tolerant bacteria from soils olive tree fields routinely treated with copper‐derived compounds evaluate tolerance bacterial strains other metals their clinically relevant antibiotics. RESULTS Five hundred ninety‐five isolates 45 agricultural were studied. Minimum inhibitory...
Sweet cherry (Prunus avium L.) is a tree widely cultivated in temperate regions for its tasty and healing fruits. Pruning works on the give each year considerable amounts of woody wastes that hardly have any utility. The aims this work were to detect most active antioxidants present pruning wood sample, isolate characterize them, study antimicrobial antibiofilm activities components found ethyl acetate extract against selection foodborne microorganisms. online HPLC–DPPH technique allowed...
Abstract Systemic inflammation is a major driver of comorbidities in people with HIV (PWH). Increased levels biomarkers enterocyte turnover, microbial translocation, and systemic have been shown to predict morbidity mortality PWH on antiretroviral therapy (ART). We conducted prospective cohort study foreign-born undetectable RNA (<20 copies/mL) without intestinal parasitic coinfection. Biomarkers turnover (intestinal fatty acid binding protein [I-FABP]), translocation (soluble CD14),...