A5059557570- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Pulmonary Hypertension Research and Treatments
- Cardiac Valve Diseases and Treatments
- Advanced MRI Techniques and Applications
- Congenital Heart Disease Studies
- Cardiovascular Disease and Adiposity
- Vascular anomalies and interventions
Linköping University
2011-2017
Örebro University
2015
Örebro University Hospital
2015
Right ventricular (RV) function is a powerful prognostic indicator in many forms of heart disease, but its assessment remains challenging and inexact. RV dysfunction may alter the normal patterns blood flow, those have been incompletely characterized. We hypothesized that, based on anatomic differences, proportions energetics flow components would differ from identified left ventricle (LV) that portion inflow passing directly to outflow (Direct Flow) be prepared for effective systolic...
Aims 4D flow magnetic resonance imaging (MRI) allows quantitative assessment of left ventricular (LV) function according to characteristics the dynamic in chamber. Marked abnormalities components’ volume and kinetic energy (KE) have previously been demonstrated moderately dilated depressed LV’s compared healthy subjects. We hypothesized that these flow-based measures would detect even subtle LV dysfunction remodeling. Methods Results acquired morphological MRI data from 26 patients with...
Purpose To investigate whether 4D flow magnetic resonance imaging (MRI) can detect subtle right ventricular (RV) dysfunction in primary left (LV) disease. Materials and Methods morphological 3T MRI data were acquired 22 patients with mild ischemic heart disease who stratified into two groups based on LV end‐diastolic volume index (EDVI): lower‐LVEDVI higher‐LVEDVI, as well 11 healthy controls. The RV was segmented at end‐diastole (ED) end‐systole (ES). Pathlines emitted from the ED traced...
Purpose To assess right ventricular (RV) turbulent kinetic energy (TKE) in patients with repaired Tetralogy of Fallot (rToF) and a spectrum pulmonary regurgitation (PR), as well to investigate the relationship between these 4D flow markers RV remodeling. Materials Methods Seventeen rToF 10 healthy controls were included study. Patients divided into two groups based on PR fraction: one lower fraction group (≤11%) higher (>11%). Field strength/sequences: 3D cine phase contrast (4D flow), 2D...
Purpose Assessment of blood flow in the left ventricle using four‐dimensional MRI requires accurate segmentation that is often hampered by low contrast between and myocardium. The purpose this work to improve left‐ventricular for reliable analysis. Method segmentations are first obtained morphological cine‐MRI with better in‐plane resolution contrast, then aligned data. This alignment is, however, not trivial due inter‐slice misalignment errors caused patient motion respiratory drift during...
Background Right ventricular (RV) function has important prognostic value in both rightand left-sided acquired and congenital heart diseases (1). Assessment of RV is challenging because its complex crescent shaped geometry load conditions being significantly influenced by respiration. Incremental insights into blood flow patterns have the potential to add our understanding (2), but remain incompletely characterized.