A5101415262- Hepatitis Viruses Studies and Epidemiology
- Viral gastroenteritis research and epidemiology
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Liver Diseases and Immunity
- Vestibular and auditory disorders
- Veterinary medicine and infectious diseases
- Diabetes and associated disorders
- Viral Infections and Immunology Research
- Ophthalmology and Eye Disorders
- Total Knee Arthroplasty Outcomes
- Systemic Lupus Erythematosus Research
- Tuberculosis Research and Epidemiology
- Chemical Synthesis and Reactions
- Asymmetric Synthesis and Catalysis
- Balance, Gait, and Falls Prevention
- HIV/AIDS oral health manifestations
- Dermatological and Skeletal Disorders
- SARS-CoV-2 and COVID-19 Research
- Obstructive Sleep Apnea Research
- Ophthalmology and Visual Impairment Studies
- Orthopedic Infections and Treatments
- Psychosomatic Disorders and Their Treatments
East Carolina University
2024
Google (United States)
2010-2024
Administración Nacional de Laboratorios e Institutos de Salud
2007-2023
Universidad Nacional de Asunción
2016-2020
Ministerio de Salud
2016
National Institutes of Health
2006-2015
University of Pennsylvania
2006-2014
Bloomsburg University
2006-2014
Hospital Muñiz
2012
After a country wide outbreak occurred during 2003-2004, 1 dose of hepatitis A vaccine was introduced into Argentinian regular immunization schedule for all children aged 12 months in June 2005. The aim this study to assess the impact novel intervention.A longitudinal analysis done virus (HAV) infection rates reported National Epidemiological Surveillance System from 2000 2011. Occurrence fulminant hepatic failure (FHF) and liver transplantation cases up 2011 were also assessed. Incidence...
Environmental surveillance of water sources is important to monitoring viral hepatitis transmission in clinical settings. This study investigated the circulation A (HAV) and E (HEV) viruses sewage samples from Argentina. Between 2016 2017, 80 raw 86 (stool serum) suspected cases were obtained. HAV HEV tested by both real-time nested PCR. Positive sequenced for genotype determination phylogenetic analysis. Overall, was recovered 39% 61.1% samples. detected 22.5% 15.9% found more frequently...
In Argentina, a country considered non-endemic for hepatitis E virus (HEV) infection, serologic evidence of HEV infection has been observed in different human population groups. other countries, high degree genetic relatedness between and swine genotype 3 sequences, suggesting zoonosis as one probable route infection. This is the first identification South America. RNA was detected sequenced ORF 1 2 regions from fecal samples herd located Pergamino, province Buenos Aires. These strains all...
Hepatitis C virus subtype 3a (HCV-3a) originates from Asia and has spread widely among injecting drug users as well other patient groups in industrialized countries. HCV infection remains highly prevalent frequently transmitted the population of intravenous users. The objective this study was to understand better mechanisms worldwide HCV-3a epidemics Ninety-three sera HCV-3a-infected IDUs France, United States, Brazil, Argentina, Australia were studied. Phylogenetic analyses non-structural...
In the past decade, organocatalytic asymmetric Michael addition has emerged as one of most important carbon-carbon bond forming reactions in organic chemistry. As an example, conjugated ketones to nitroolefins received extensive attention, since resulting nitroalkanes are versatile intermediates which nitro group can be transformed into various useful functional groups. Furthermore, reaction ability introduce two vicinal stereogenic centers a single step. Stimulated by seminal work List,...
Single-dose hepatitis A virus (HAV) vaccination was implemented in all Argentinean children 12 months of age 2005. Previous studies demonstrated high prevalence protective antibody response 4 years after single-dose vaccination. This study assessed long-term seroprotection against HAV vaccination.Children who received 1 dose vaccine at year least 6 before enrollment were included 5 centers Argentina between 2013 and 2014. Demographic socioeconomic characteristics collected through a...
ABSTRACT A number of reports have indicated an increased risk cirrhosis and hepatocellular carcinoma in hepatitis B virus (HBV)-infected individuals carrying HBV e antigen (HBeAg)-negative variants. Although distinct core promoter precore mutations distributed according to geographical locality viral genotype been reported, epidemiological data from South America are still scarce. The prevalences genotypes polymorphisms 75 HBeAg-negative Argentinean blood donors were surveyed. observed...
Hepatitis E is a disease of global distribution, with significant morbidity and mortality, whose scope burden continue to emerge in low endemic countries.In 2012, we studied the prevalence anti-HEV antibodies 202 adult serum samples. We also analyzed samples from 143 patients acute non-A-C hepatitis January 2011 December 2013. Acute HEV infections were diagnosed IgM and/or RNA. RNA was investigated 94 swine fecal sequenced characterized.We found higher values than those previously reported...
Single-dose hepatitis A virus (HAV) vaccination was implemented in all Argentinean children aged 12 months 2005. Between 2005 and 2011, a dramatic decline observed HAV infection rates, fulminant hepatitis, liver transplantation. This study assessed current viral circulation estimated protective antibody persistence 4 years after vaccination. Prevalence of prevaccination anti-HAV antibodies 12-month-old evaluated as an indirect estimation (Group A). Seroprevalence also measured 5-year-old who...
Abstract Background Hepatitis E virus (HEV) has been described as an emerging pathogen in Brazil and seems to be widely disseminated among swine herds. An autochthonous human case of acute hepatitis was recently reported. To obtain a better understanding the phenotypic profiles both HEV strains, experimental study conducted using animal model, Macaca fascicularis . Methods Six cynomolgus monkeys ( ) were inoculated intravenously with genotype 3 that isolated from naturally experimentally...
Abstract Background: Hepatitis A infection, a vaccine‐preventable disease, is an important cause of fulminant hepatic failure (FHF) in children Argentina. Universal vaccination 1‐year‐old was implemented June 2005. The limited studies about the correlation between characteristics hepatitis virus (HAV) and FHF have been carried out adults. Methods: Samples from 41 with were studied September 2003 to January 2006 HAV RNA detected, sequenced analysed 5′ non‐coding region VP1/2A region. Results:...
Hepatitis A, a vaccine preventable disease, is now of transitional or intermediate endemicity in Argentina, as the epidemiologic pattern disease has shifted with improvements living conditions some parts country. Increase susceptibility older children and adults led to increasing incidence. Molecular epidemiology played an important role understanding HAV infection by identifying modes spreading permitting monitoring changes circulating virus brought about prevention programs. South American...
Introducción: La planificación preoperatoria favorece la realización de un acto quirúrgico sin complicaciones. Actualmente existe escasa información a nivel nacional sobre eficacia pre-operatoria digital por lo que el objetivo del presente estudio es analizar los resultados implementación esta estrategia en una población pacientes con indicación artroplastia total cadera.
To investigate the detection of hepatitis A virus ribonucleic acid in patients with acute liver failure and to assess if results have any clinical implications for evolution children. Hepatitis infection, a vaccine-preventable disease, is an important cause children Argentina. Universal vaccination 1-yr-old was implemented June 2005.Observational study which were divided into Group 1 consisting positive 2 negative acid.Pediatric intensive care unit National Pediatric Hospital "Dr. J. P....