A5061909481- Advanced Glycation End Products research
- Natural Antidiabetic Agents Studies
- Gut microbiota and health
- Neurological Disorders and Treatments
- Ginger and Zingiberaceae research
- Garlic and Onion Studies
- Adipose Tissue and Metabolism
- Nutritional Studies and Diet
- Genetic Syndromes and Imprinting
- Phytochemistry and biological activity of medicinal plants
- Probiotics and Fermented Foods
- Biochemical Analysis and Sensing Techniques
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Metabolism, Diabetes, and Cancer
- Animal Nutrition and Physiology
- Ziziphus Jujuba Studies and Applications
- Patient Satisfaction in Healthcare
- Adipokines, Inflammation, and Metabolic Diseases
- Phytochemicals and Antioxidant Activities
- Oral microbiology and periodontitis research
- Celiac Disease Research and Management
- Diet and metabolism studies
- Salivary Gland Disorders and Functions
- Sirtuins and Resveratrol in Medicine
- Bioactive Compounds and Antitumor Agents
Shandong First Medical University
2010-2023
Institute of Endocrinology
2019-2020
Academy of Medical Sciences
2010
The relationship between type 2 diabetes mellitus (T2DM) and oral microbiota is still insufficiently recognized. In the present study, we compared salivary microbiome of nondiabetic individuals, treatment-naïve diabetic patients, patients treated with metformin or a combination insulin other drugs. α- β-diversity demonstrated significant differences in people history diabetes, while little divergence was found among individuals diabetes. After characterizing effects periodontitis on...
Advanced glycation end products (AGEs) cause damage to pancreatic β-cells and trigger oxidative stress inflammation, which promotes the development progression of diabetes its complications. Therefore, it is important inhibit formation AGEs as part treatment diabetes. Allicin a natural antimicrobial agent with abundant pharmacological activities, recent studies have reported therapeutic effects in diabetes; however, mechanism these still unclear. Thus, purpose this study was further...
This study aimed to observe the hypoglycemic effect of cassia seed extract in rats with type-2 diabetes mellitus and its on reducing insulin resistance skeletal muscle.50 were randomly divided into normal, model, high-dose, middle-dose, low-dose groups (n = 10 each). A high-fat diet combined streptozotocin administration was adopted build type 2 models. The fed different concentrations while normal model same volume saline. weight, FINS, GIR, tolerance, blood glucose lipid level, oxidative...
Introduction Allicin is a wide spectrum prebiotic for human health, but whether it can attenuate blood in diabetes patients rarely reported. In this study, we built rat model and investigated the effect of allicin on mellitus type 2 (T2DM). We found that could effectively reduce glucose levels, regulate intestinal microbiota, lipid body weight accumulation, systemic inflammation T2DM rats. Methods The was made by streptozotocin, different doses were given orally gavage. contents rats...
Background: Diabetes has become a problem that plagues public healthcare systems. Recent studies have shown intestinal flora exerts positive therapeutic effects on metabolic diseases, and plant-derived secondary metabolites are safe, effective easy to prepare also an impact diabetes; these drugs rarely been reviewed before as class of for diabetes, especially focusing the flora. Therefore, studying relationship between diabetes mellitus is crucial. Objective: The objective this study...
Recent data showed that 9.1% of adults worldwide have diabetes, and 318 million a high risk developing diabetes in the future.Diabetes its complications serious impact on human health.In early stages excessive advanced glycation endproducts (AGEs) accumulate body bind to receptor RAGE, which impairs glucose regulation.In later increased blood can accelerate production more AGEs.AGEs play pivotal role development complications.In recent years, AGEs become one research hotspots.The search for...
Recent data showed that 9.1% of adults worldwide have diabetes, and 318 million a high risk developing diabetes in the future.Diabetes its complications serious impact on human health.In early stages excessive advanced glycation endproducts (AGEs) accumulate body bind to receptor RAGE, which impairs glucose regulation.In later increased blood can accelerate production more AGEs.AGEs play pivotal role development complications.In recent years, AGEs become one research hotspots.The search for...