A5101730413- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Immune Cell Function and Interaction
- Diabetes Treatment and Management
- Glutathione Transferases and Polymorphisms
- Pancreatic function and diabetes
- Metabolism, Diabetes, and Cancer
- Diabetes Management and Education
- Sirtuins and Resveratrol in Medicine
- Cancer-related gene regulation
- Thyroid Disorders and Treatments
- Regulation of Appetite and Obesity
- Blood Pressure and Hypertension Studies
- Adipose Tissue and Metabolism
- Ferroptosis and cancer prognosis
- Chronic Disease Management Strategies
- Epigenetics and DNA Methylation
- Adipokines, Inflammation, and Metabolic Diseases
- Diabetes Management and Research
- Cancer, Lipids, and Metabolism
- Quinazolinone synthesis and applications
- Bacteriophages and microbial interactions
- RNA modifications and cancer
- Pharmacology and Obesity Treatment
Linyi People's Hospital
2018-2021
Lishui Central Hospital
2016
Chinese PLA General Hospital
2009
Objective: This study aimed to construct a prognostic ferroptosis-related signature for thyroid cancer and probe into the association with tumor immune microenvironment. Methods: Based on expression profiles of genes, LASSO cox regression model was established cancer. Kaplan-Meier survival analysis presented between high low risk groups. The predictive performance assessed by ROC. independency validated via multivariate stratified analysis. A nomogram verified calibration curves. enriched...
Type 2 diabetes mellitus (T2D) is a common endocrine and metabolic disorder, poses threats to human health worldwide.Recently, microRNAs (miRNAs) have been suggested play important roles in the pathophysiology of T2D.In this study, we explored role miR-3666 T2D.miR-3666 was significantly down-regulated serum T2D patients when compared that healthy volunteers, expression level negatively correlated with blood glucose levels patients.Overexpression inhibited cell proliferation, reduced insulin...
This study aimed to observe the hypoglycemic effect of cassia seed extract in rats with type-2 diabetes mellitus and its on reducing insulin resistance skeletal muscle.50 were randomly divided into normal, model, high-dose, middle-dose, low-dose groups (n = 10 each). A high-fat diet combined streptozotocin administration was adopted build type 2 models. The fed different concentrations while normal model same volume saline. weight, FINS, GIR, tolerance, blood glucose lipid level, oxidative...
Abstract Ring1 and YY1 binding protein (RYBP), a new member of the polycomb group family, has been reported to play an important role in various biological processes. Recently, more studies have demonstrated implication RYBP cancer development. However, specific anaplastic thyroid (ATC) remains unknown. In this study, we investigated for first time expression pattern functions ATC. We showed that was lowly expressed ATC tissues cell lines. also found overexpression inhibited proliferation,...
Through our previous work, we have identified that novel oxazolidinone structures, the biaryloxazolidinone analogues containing a hydrazone moiety, act as promising antibacterial agents against gram-positive bacterial strains. Based on this active structure, in study, synthesized series of oxazolidinones and determined their anti-mycobacterial activities vitro Mycobacterium marinum-infected zebrafish. The assay demonstrated all compounds potent efficacy both H37Rv clinical mycobacterial...