Genhai Zhao

ORCID: 0000-0001-6343-6053
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About
Contact & Profiles
Research Areas
  • Vitamin K Research Studies
  • Microbial Metabolic Engineering and Bioproduction
  • Vitamin C and Antioxidants Research
  • Enzyme Catalysis and Immobilization
  • Enzyme Production and Characterization
  • Biofuel production and bioconversion
  • Fermentation and Sensory Analysis
  • Fungal and yeast genetics research
  • Plant biochemistry and biosynthesis
  • Enzyme Structure and Function
  • Analytical chemistry methods development
  • Calcium Carbonate Crystallization and Inhibition
  • Chromium effects and bioremediation
  • Steroid Chemistry and Biochemistry
  • Microbial metabolism and enzyme function
  • Tannin, Tannase and Anticancer Activities
  • Microbial Natural Products and Biosynthesis
  • Toxic Organic Pollutants Impact
  • Phytochemicals and Antioxidant Activities
  • Effects and risks of endocrine disrupting chemicals
  • Food Quality and Safety Studies
  • Aldose Reductase and Taurine
  • Amino Acid Enzymes and Metabolism
  • Mycotoxins in Agriculture and Food
  • Hormonal Regulation and Hypertension

Chinese Academy of Sciences
2014-2024

Hefei Institutes of Physical Science
2015-2024

Jiangnan University
2004-2024

Institute of Intelligent Machines
2021-2024

Heilongjiang Provincial Academy of Agricultural Sciences
2019

Harbin University of Commerce
2019

Academy of State Administration of Grain
2019

Hefei University
2014

Nanjing University
2010

Harbin Institute of Technology
2008

A non-linear kinetic model to predict the consumption of different sugars (glucose, fructose and sucrose) as a substrate, during an apple wine yeast fermentation with Saccharomyces cerevisiae strain CCTCC M201022 is proposed. This was used sugar utilization by this beginning at various initial concentrations. After observation experimental data, based on logistic equation growth, growth-associated production ethanol lag time, for biomass formation maintenance, developed. fitting, parameters...

10.1002/j.2050-0416.2004.tb00630.x article EN Journal of the Institute of Brewing 2004-01-01

Flavor volatiles are important components of alcoholic beverages. In this study, headspace solid-phase microextraction and gas chromatography—mass spectrometry (HS-SPME-GC-MS) were investigated for the determination flavor-contributing apple wine. HS-SPME parameters defined, including fiber coatings, extraction time, temperature. Good linearity, recoveries, repeatability SPME method using carboxen-polydimethylsiloxane (carboxen-PDMS) obtained with r2 values, relative standard deviations...

10.1002/j.2050-0416.2004.tb00181.x article EN Journal of the Institute of Brewing 2004-01-01

The aim of this study was to enhance the production vitamin K2 by using N-methyl-N-nitro-N-nitroso-guanidine (NTG) and low energy ion beam implantation optimizing fermentation medium. Mutation resulted in 1.66-fold higher than that parentl strain. mutant BN-P15-11-1was increased 55% reached 3.593±0.107 mg/L Plackett-Burman Box-Behnken designs optimize optimal culture medium composed (g/L) glycerol 69.6, sucrose 34.5, K2HPO4 4.0, peptone 20, yeast extract 25 fermented at 37 °C 150 rpm for 72...

10.1590/s1516-8913201402126 article EN cc-by-nc Brazilian Archives of Biology and Technology 2014-08-01

Vitamin K2, a natural fat-soluble vitamin, is potent neuroprotective molecule, owing to its antioxidant effect, but mechanism has not been fully elucidated. Therefore, we stimulated SH-SY5Y cells with 6-hydroxydopamine (6-OHDA) in proper dose-dependent manner, followed by treatment of vitamin K2. In the presence 6-OHDA, cell viability was reduced, mitochondrial membrane potential decreased, and accumulation reactive oxygen species (ROS) increased. Moreover, 6-OHDA promoted...

10.3390/nu14071504 article EN Nutrients 2022-04-04

Menaquinone-7 (MK-7), which is associated with complex and tightly regulated pathways redox imbalances, produced at low titres in Bacillus subtilis. Synthetic biology provides a rational engineering principle for the transcriptional optimisation of key enzymes artificial creation cofactor regeneration systems without regulatory interference. This holds great promise alleviating pathway bottlenecks improving efficiency carbon energy utilisation.We used bottom-up synthetic approach redesign...

10.1186/s12934-022-01823-3 article EN cc-by Microbial Cell Factories 2022-05-28

A method for the preparation of volatile compounds in Changyu XO brandy was established. The were extracted using liquid-liquid extraction and then separated into two fractions, namely, acidic/water-soluble fraction neutral/basic fraction. furthermore 4 fractions silica gel normal phase chromatography, each concentrated analyzed gas chromatography-mass spectrometry (GC-MS). In comparison with pure standards retention indices (RIs) reported literature, a total 302 identified brandy, including...

10.1016/s1872-2059(08)60014-0 article EN Chinese Journal of Chromatography 2008-03-01
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