Magdalena Kayser

ORCID: 0000-0001-6387-4889
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About
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Research Areas
  • CAR-T cell therapy research
  • Cancer Immunotherapy and Biomarkers
  • Biosimilars and Bioanalytical Methods
  • Immunotherapy and Immune Responses

Cancer continues to be the leading cause of mortality in high-income countries, necessitating development more precise and effective treatment modalities. Immunotherapy, specifically adoptive cell transfer T receptor (TCR)-engineered cells (TCR-T therapy), has shown promise engaging immune system for cancer treatment. One biggest challenges TCR-T therapies is proper prediction pairing between TCRs peptide-human leukocyte antigen (pHLAs). Modern computational immunology, using artificial...

10.2196/45872 article EN cc-by JMIR Research Protocols 2023-06-02

<sec> <title>BACKGROUND</title> Cancer continues to be the leading cause of mortality in high-income countries, necessitating development more precise and effective treatment modalities. Immunotherapy, specifically adoptive cell transfer T receptor (TCR)-engineered cells (TCR-T therapy), has shown promise engaging immune system for cancer treatment. One biggest challenges TCR-T therapies is proper prediction pairing between TCRs peptide-human leukocyte antigen (pHLAs). Modern computational...

10.2196/preprints.45872 preprint EN 2023-02-08
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