Nick Johnson

ORCID: 0000-0001-6389-2112
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About
Contact & Profiles
Research Areas
  • Monoclonal and Polyclonal Antibodies Research
  • Advanced Biosensing Techniques and Applications
  • Biosimilars and Bioanalytical Methods
  • Enzyme Catalysis and Immobilization
  • Microbial Metabolic Engineering and Bioproduction
  • Parallel Computing and Optimization Techniques
  • Advanced Wireless Network Optimization
  • Chemical Synthesis and Analysis
  • Software-Defined Networks and 5G
  • Single-cell and spatial transcriptomics
  • Advanced Data Storage Technologies
  • Wireless Networks and Protocols
  • Distributed and Parallel Computing Systems
  • Cell Image Analysis Techniques
  • Network Traffic and Congestion Control
  • Sparse and Compressive Sensing Techniques
  • Privacy-Preserving Technologies in Data
  • Mobile Ad Hoc Networks
  • Space exploration and regulation
  • Opportunistic and Delay-Tolerant Networks
  • Substance Abuse Treatment and Outcomes
  • Advanced Optical Network Technologies
  • Alcohol Consumption and Health Effects
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Electrochemical sensors and biosensors

University of Edinburgh
2009-2024

Colorado State University
2019

Engineering and Physical Sciences Research Council
2017

Femtocells are low-power cellular base stations that operate in licensed spectrum. They typically deployed indoors to improve coverage and provide excellent user experience, including high data rates. Cellular operators benefit from reduced infrastructure operational expenses for capacity upgrades improvements. also bring unique challenges, such as unplanned deployment, installation, restricted access, interoperability with existing handsets network infrastructure. Although femtocells may...

10.1109/mcom.2009.5277462 article EN IEEE Communications Magazine 2009-09-01

Memory and I/O performance bottlenecks in supercomputing simulations are two key challenges that must be addressed on the road to Exascale. The new byte-addressable persistent non-volatile memory technology from Intel, DCPMM, promises an exciting opportunity break with status quo, unprecedented levels of capacity at near-DRAM speeds. Here, we explore potential DCPMM context high-performance scientific applications terms outright performance, efficiency usability for both its App Direct...

10.1145/3295500.3356159 article EN 2019-11-07

Biocompatible chemistry enables abiotic reactions to be interfaced with metabolic pathways in living microorganisms. This includes both native and de novo biosynthetic processes access feedstocks, intermediates products vivo. Herein we report a biocompatible Lossen rearrangement that is catalysed by phosphate the bacterium Escherichia coli for chemical transformation of activated acyl hydroxamates primary amines cells. Using para-carboxylated substrate, reaction can used generate metabolite...

10.26434/chemrxiv-2024-g4sbt preprint EN cc-by-nc 2024-01-23

Byte-addressable storage class memory (SCM) is an upcoming technology that will transform the and hierarchy of HPC systems by dramatically reducing latency gap between DRAM persistent storage. In this paper, we discuss general SCM characteristics, including different hardware configurations data access mechanisms likely to provide. We outline performance challenges I/O requirements place on traditional scientific workflows present how through can have a beneficial impact such workflows, in...

10.14529/jsfi180105 article EN cc-by Supercomputing Frontiers and Innovations 2018-03-01

Research exploring American Indian (AI) youth drinking motives and their relation to negative outcomes is critical due higher rates of alcohol use early exposure intoxication in the population. The purpose this study explore classes as they relate heavy episodic drinking, perceived discrimination, religious importance, ethnic identity, pride. This part an ongoing epidemiologic etiologic investigation substance among AI drinkers living on or near reservations (n = 1,934, Mage 15.31). A latent...

10.1037/adb0000469 article EN publisher-specific-oa Psychology of Addictive Behaviors 2019-05-13

Small molecule organocatalysts are abundant in all living organisms. However, their use as cells has been underexplored. Herein, we report that organocatalytic aldol chemistry can be interfaced with Escherichia coli to enable the α-methylenation of cellular aldehydes using biogenic amines such L-Pro or phosphate. The biocompatible reaction is mild and butyraldehyde generated from D-glucose via engineered metabolism production 2-methylenebutanal (2-MB) 2-methylbutanal (2-MBA) by anaerobic...

10.1002/anie.202306347 article EN cc-by Angewandte Chemie International Edition 2023-07-21

CityFlow is an EU FP7 project, aiming to create a set of multi-autonomous-system OpenFlow experiments on the OFELIA infrastructure emulate city one million inhabitants. In this demo, we demonstrate all key components experimentation stack working together.

10.1109/ewsdn.2014.40 article EN 2014-09-01

Biocompatible chemistry enables abiotic reactions to be interfaced with metabolic pathways in living microorganisms. This includes both native and de novo biosynthetic processes access feedstocks, intermediates products vivo. Herein we report a biocompatible Lossen rearrangement that is catalysed by phosphate the bacterium Escherichia coli for chemical transformation of activated acyl hydroxamates primary amines cells. Using para-carboxylated substrate, reaction can used generate metabolite...

10.26434/chemrxiv-2024-g4sbt-v2 preprint EN cc-by-nc 2024-12-17

Network tomography offers a useful method to identify internal problems in network using data which can be obtained at the network's edge. Provided topology of is known then it possible recover from edge measurements some properties links may not accessible for any number reasons - cost, ownership, physical location etc. In this paper we introduce two new estimation algorithms based on Pearson type-1 distribution and compare these with existing estimator detector used find bottleneck link...

10.5281/zenodo.41635 article EN 2009-08-24

In this paper, we propose an OpenFlow enabled Internet infrastructure, using virtual path slicing in end-to-end path, so that any user connected to network is dynamically allocated a corresponding right of way. This approach allows interference-free from other traffic, between two endpoints, on multiple autonomous systems, for given application flow (e.g., WebHD Video Streaming). Additionally, and implement quality service framework the Future extend slice engine support future technologies...

10.23919/inm.2017.7987289 article EN 2017-05-01

Abstract Small molecule organocatalysts are abundant in all living organisms. However, their use as cells has been underexplored. Herein, we report that organocatalytic aldol chemistry can be interfaced with Escherichia coli to enable the α‐methylenation of cellular aldehydes using biogenic amines such L‐Pro or phosphate. The biocompatible reaction is mild and butyraldehyde generated from D‐glucose via engineered metabolism production 2‐methylenebutanal (2‐MB) 2‐methylbutanal (2‐MBA) by...

10.1002/ange.202306347 article EN cc-by Angewandte Chemie 2023-07-21
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